Summary

This strain contains 18 protein-level mutations:

  • 5 mutations in Spike protein: L452R, T478K, D614G, P681R, D950N
  • 3 mutations in N protein: D63G, R203M, G215C
  • 1 mutation in M protein: I82T
  • 1 mutation in NS3 protein: S26L
  • 2 mutations in NS7a protein: V82A, T120I
  • 1 mutation in NS9b protein: T60A
  • 1 mutation in NS9c protein: G50W
  • 2 mutations in NSP3 protein: A488S, P1469S
  • 1 mutation in NSP12 protein: P323L
  • 1 mutation in NSP14 protein: 413-415 GCD->LNY

We identified all possible linear viral peptides affected by these mutations. Whenever it was possible, we matched the reference peptide with the mutated one. For example, D -> L mutation transformed SDNGPQNQR to SLNGPQNQR. Cases when it was not meaningful included deletions and insertions at the flanks of the peptide, e.g., HV deletion in NVTWFHAIHV peptide.

Then, we predicted binding affinities between the selected peptides and frequent HLA alleles. Predictions were made with NetMHCpan-4.1 and NetMHCIIpan-4.0. The binding affinities were classifies into three groups:

  1. Tight binding (IC50 affinity ≤ 50 nM)
  2. Moderate binding (50 nM < IC50 affinity ≤ 500 nM)
  3. Weak/no binding (IC50 affinity > 500 nM)

Here we report HLA-peptide interactions whose affinity was altered by at least two folds. Note that mutations with empty set of altered interactions are not showed.

The total number of HLA-peptide interactions affected by the mutations

For each allele we calculated the number of peptides with increased and decreased affinitiy (two or more times). The absolute number of such peptides is showed on the left side of the figure (blue bars — weaker binding, orange bars — stronger).

While absolute numbers are of interest, they do not reflect the initial number of tighly binding peptides for the specific allele. Roughly speaking, if an allele had high number of tight binders, then vanished affinity of several peptides will not affect much the integral ability of peptide presentation. To the contrary, low number of vanished peptides could be important if the particular allele initially had narrow epitope repertoire. To account for this effect, we normalized the absolute numbers of new/vanished tight binders (IC50 affinity ≤ 50 nM) by the total number of tight binders for each allele. To avoid possible divisions by zero, we used + 1 regularization term in all denominators. For example, if some allele had no tight binders in the reference genome, and three new tight binders appeared as a result of the mutation, the relative increase will be 300%. The results are showed in the right part of the figure. Protein-specific plots are listed below.

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Summary

Spike protein

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Spike

L452R

Reference  DDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGS
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Mutated    DDFTGCVIAWNSNNLDSKVGGNYNYRYRLFRKSNLKPFERDISTEIYQAGS

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Allele Reference peptide Mutated peptide Reference affinity (IC50, nM) Mutated affinity (IC50, nM)
HLA-DPA1*03:01/DPB1*02:01 LDSKVGGNYNYLYRL LDSKVGGNYNYRYRL 424 3666
HLA-DPA1*03:01/DPB1*02:01 WNSNNLDSKVGGNYNYLYRL WNSNNLDSKVGGNYNYRYRL 415 2864
HLA-DPA1*03:01/DPB1*02:01 NLDSKVGGNYNYLYRLFRK NLDSKVGGNYNYRYRLFRK 144 966
HLA-DPA1*03:01/DPB1*02:01 LDSKVGGNYNYLYRLFR LDSKVGGNYNYRYRLFR 249 1634
HLA-DPA1*03:01/DPB1*02:01 NNLDSKVGGNYNYLYRLFRK NNLDSKVGGNYNYRYRLFRK 113 734
HLA-DPA1*03:01/DPB1*04:01 DSKVGGNYNYLYRLFR DSKVGGNYNYRYRLFR 392 2542
HLA-DPA1*03:01/DPB1*04:01 NLDSKVGGNYNYLYRLFRK NLDSKVGGNYNYRYRLFRK 305 1960
HLA-DPA1*03:01/DPB1*02:01 NNLDSKVGGNYNYLYRLFR NNLDSKVGGNYNYRYRLFR 218 1391
HLA-DPA1*03:01/DPB1*04:01 NNLDSKVGGNYNYLYRLFRK NNLDSKVGGNYNYRYRLFRK 256 1631
HLA-DPA1*03:01/DPB1*04:01 SNNLDSKVGGNYNYLYRLFR SNNLDSKVGGNYNYRYRLFR 345 2181
HLA-DPA1*03:01/DPB1*02:01 DSKVGGNYNYLYRLFRK DSKVGGNYNYRYRLFRK 173 1093
HLA-DPA1*03:01/DPB1*04:01 SKVGGNYNYLYRLFR SKVGGNYNYRYRLFR 359 2266
HLA-DPA1*03:01/DPB1*04:01 NNLDSKVGGNYNYLYRLFR NNLDSKVGGNYNYRYRLFR 401 2531
HLA-DPA1*03:01/DPB1*02:01 SNNLDSKVGGNYNYLYRLFR SNNLDSKVGGNYNYRYRLFR 172 1064
HLA-DPA1*03:01/DPB1*02:01 SKVGGNYNYLYRLFR SKVGGNYNYRYRLFR 196 1212
HLA-DPA1*03:01/DPB1*02:01 SKVGGNYNYLYRLFRK SKVGGNYNYRYRLFRK 144 883
HLA-DPA1*03:01/DPB1*04:01 LDSKVGGNYNYLYRLFR LDSKVGGNYNYRYRLFR 441 2693
HLA-DPA1*03:01/DPB1*02:01 DSKVGGNYNYLYRLFR DSKVGGNYNYRYRLFR 218 1325
HLA-DPA1*03:01/DPB1*02:01 DSKVGGNYNYLYRLF DSKVGGNYNYRYRLF 261 1555
HLA-DPA1*03:01/DPB1*02:01 NLDSKVGGNYNYLYRLF NLDSKVGGNYNYRYRLF 361 2150
HLA-DPA1*03:01/DPB1*04:01 KVGGNYNYLYRLFRK KVGGNYNYRYRLFRK 305 1801
HLA-DPA1*03:01/DPB1*04:01 SKVGGNYNYLYRLFRK SKVGGNYNYRYRLFRK 309 1809
HLA-DPA1*03:01/DPB1*04:02 NNLDSKVGGNYNYLYRLFRK NNLDSKVGGNYNYRYRLFRK 444 2598
HLA-DPA1*03:01/DPB1*02:01 KVGGNYNYLYRLFRK KVGGNYNYRYRLFRK 143 835
HLA-DPA1*03:01/DPB1*02:01 SNNLDSKVGGNYNYLYRLF SNNLDSKVGGNYNYRYRLF 324 1887
HLA-DPA1*03:01/DPB1*02:01 NSNNLDSKVGGNYNYLYRLF NSNNLDSKVGGNYNYRYRLF 252 1455
HLA-DPA1*03:01/DPB1*04:01 DSKVGGNYNYLYRLFRK DSKVGGNYNYRYRLFRK 351 2010
HLA-DPA1*03:01/DPB1*02:01 LDSKVGGNYNYLYRLF LDSKVGGNYNYRYRLF 295 1679
HLA-DPA1*03:01/DPB1*02:01 NLDSKVGGNYNYLYRLFR NLDSKVGGNYNYRYRLFR 455 2516
HLA-DPA1*03:01/DPB1*02:01 LDSKVGGNYNYLYRLFRK LDSKVGGNYNYRYRLFRK 304 1659
HLA-DPA1*03:01/DPB1*01:01 NNLDSKVGGNYNYLYRLFRK NNLDSKVGGNYNYRYRLFRK 244 1247
HLA-DPA1*01:03/DPB1*02:01 SNNLDSKVGGNYNYLYRLFR SNNLDSKVGGNYNYRYRLFR 439 2221
HLA-DPA1*01:03/DPB1*02:01 NNLDSKVGGNYNYLYRLFRK NNLDSKVGGNYNYRYRLFRK 317 1603
HLA-DPA1*03:01/DPB1*01:01 SNNLDSKVGGNYNYLYRLFR SNNLDSKVGGNYNYRYRLFR 342 1688
HLA-DPA1*03:01/DPB1*01:01 DSKVGGNYNYLYRLFR DSKVGGNYNYRYRLFR 424 2025
HLA-DPA1*03:01/DPB1*01:01 NLDSKVGGNYNYLYRLFRK NLDSKVGGNYNYRYRLFRK 322 1525
HLA-DPA1*01:03/DPB1*02:01 NLDSKVGGNYNYLYRLFRK NLDSKVGGNYNYRYRLFRK 457 2136
HLA-DPA1*03:01/DPB1*01:01 NNLDSKVGGNYNYLYRLFR NNLDSKVGGNYNYRYRLFR 422 1941
HLA-DRB1*11:01 GGNYNYLYRLFRKSN GGNYNYRYRLFRKSN 37 169
HLA-DRB1*11:01 KVGGNYNYLYRLFRKSN KVGGNYNYRYRLFRKSN 72 326
HLA-DRB1*11:01 VGGNYNYLYRLFRKSN VGGNYNYRYRLFRKSN 82 368
HLA-DPA1*03:01/DPB1*01:01 LDSKVGGNYNYLYRLFR LDSKVGGNYNYRYRLFR 471 2092
HLA-DPA1*03:01/DPB1*01:01 DSKVGGNYNYLYRLFRK DSKVGGNYNYRYRLFRK 364 1596
HLA-DPA1*03:01/DPB1*01:01 SKVGGNYNYLYRLFRK SKVGGNYNYRYRLFRK 324 1420
HLA-DPA1*03:01/DPB1*01:01 NSNNLDSKVGGNYNYLYRLF NSNNLDSKVGGNYNYRYRLF 478 2087
HLA-DPA1*04:01/DPB1*04:01 KVGGNYNYLYRLFRK KVGGNYNYRYRLFRK 445 1918
HLA-DPA1*04:01/DPB1*04:01 SKVGGNYNYLYRLFRK SKVGGNYNYRYRLFRK 499 2113
HLA-DRB1*11:01 KVGGNYNYLYRLFRK KVGGNYNYRYRLFRK 64 271
HLA-DPA1*03:01/DPB1*01:01 KVGGNYNYLYRLFRK KVGGNYNYRYRLFRK 337 1420
HLA-DPA1*02:02/DPB1*01:01 SKVGGNYNYLYRLFR SKVGGNYNYRYRLFR 483 2032
HLA-DPA1*04:01/DPB1*04:01 NNLDSKVGGNYNYLYRLFRK NNLDSKVGGNYNYRYRLFRK 405 1699
HLA-DPA1*01:03/DPB1*02:01 KVGGNYNYLYRLFRK KVGGNYNYRYRLFRK 390 1622
HLA-DPA1*01:03/DPB1*02:01 SKVGGNYNYLYRLFRK SKVGGNYNYRYRLFRK 458 1904
HLA-DPA1*03:01/DPB1*01:01 SKVGGNYNYLYRLFR SKVGGNYNYRYRLFR 450 1858
HLA-DRB1*11:01 SKVGGNYNYLYRLFRK SKVGGNYNYRYRLFRK 145 597
HLA-DRB1*11:01 DSKVGGNYNYLYRLFRK DSKVGGNYNYRYRLFRK 133 541
HLA-DRB1*11:01 SKVGGNYNYLYRLFR SKVGGNYNYRYRLFR 144 581
HLA-DPA1*02:02/DPB1*01:01 DSKVGGNYNYLYRLFRK DSKVGGNYNYRYRLFRK 384 1511
HLA-DPA1*02:02/DPB1*01:01 NLDSKVGGNYNYLYRLFRK NLDSKVGGNYNYRYRLFRK 390 1497
HLA-DPA1*02:02/DPB1*01:01 KVGGNYNYLYRLFRK KVGGNYNYRYRLFRK 354 1357
HLA-DRB1*11:01 DSKVGGNYNYLYRLFR DSKVGGNYNYRYRLFR 357 1364
HLA-DRB1*11:01 SKVGGNYNYLYRLFRKSN SKVGGNYNYRYRLFRKSN 281 1070
HLA-DPA1*02:02/DPB1*01:01 SKVGGNYNYLYRLFRK SKVGGNYNYRYRLFRK 364 1384
HLA-DRB1*11:01 LDSKVGGNYNYLYRLFR LDSKVGGNYNYRYRLFR 344 1295
HLA-DPA1*02:02/DPB1*01:01 NNLDSKVGGNYNYLYRLFRK NNLDSKVGGNYNYRYRLFRK 323 1186
HLA-DRB1*11:01 KVGGNYNYLYRLFRKS KVGGNYNYRYRLFRKS 114 416
HLA-DRB1*11:01 DSKVGGNYNYLYRLFRKSN DSKVGGNYNYRYRLFRKSN 134 485
HLA-DRB1*11:01 VGGNYNYLYRLFRKS VGGNYNYRYRLFRKS 50 179
HLA-DRB1*11:01 SKVGGNYNYLYRLFRKS SKVGGNYNYRYRLFRKS 102 357
HLA-DQA1*01:02/DQB1*05:01 VGGNYNYLYRLFRKSN VGGNYNYRYRLFRKSN 216 735
HLA-DRB1*11:01 DSKVGGNYNYLYRLFRKS DSKVGGNYNYRYRLFRKS 383 1300
HLA-DRB1*11:04 VGGNYNYLYRLFRKSN VGGNYNYRYRLFRKSN 75 254
HLA-DPA1*02:02/DPB1*01:01 SNNLDSKVGGNYNYLYRLFR SNNLDSKVGGNYNYRYRLFR 489 1656
HLA-DRB1*10:01 KVGGNYNYLYRLFRK KVGGNYNYRYRLFRK 275 922
HLA-DRB1*11:01 LDSKVGGNYNYLYRLFRKSN LDSKVGGNYNYRYRLFRKSN 83 278
HLA-DRB1*11:01 NLDSKVGGNYNYLYRLFRK NLDSKVGGNYNYRYRLFRK 258 850
HLA-DRB1*10:01 DSKVGGNYNYLYRLFRK DSKVGGNYNYRYRLFRK 417 1367
HLA-DRB1*10:01 SKVGGNYNYLYRLFR SKVGGNYNYRYRLFR 420 1370
HLA-DRB1*16:01 KVGGNYNYLYRLFRK KVGGNYNYRYRLFRK 189 605
HLA-DPA1*02:02/DPB1*05:01 KVGGNYNYLYRLFRK KVGGNYNYRYRLFRK 351 1116
HLA-DRB1*11:04 GGNYNYLYRLFRKSN GGNYNYRYRLFRKSN 32 101
HLA-DPA1*02:02/DPB1*05:01 DSKVGGNYNYLYRLFRK DSKVGGNYNYRYRLFRK 425 1331
HLA-DRB1*16:01 SKVGGNYNYLYRLFR SKVGGNYNYRYRLFR 482 1504
HLA-DQA1*01:02/DQB1*05:01 KVGGNYNYLYRLFRKS KVGGNYNYRYRLFRKS 164 508
HLA-DPA1*02:02/DPB1*05:01 SKVGGNYNYLYRLFRK SKVGGNYNYRYRLFRK 446 1378
HLA-DPA1*03:01/DPB1*04:01 LDSKVGGNYNYLYRLFRKS LDSKVGGNYNYRYRLFRKS 200 617
HLA-DPA1*03:01/DPB1*04:01 DSKVGGNYNYLYRLFRKSN DSKVGGNYNYRYRLFRKSN 193 592
HLA-DRB1*10:01 SKVGGNYNYLYRLFRK SKVGGNYNYRYRLFRK 447 1369
HLA-DRB1*11:01 LDSKVGGNYNYLYRLFRKS LDSKVGGNYNYRYRLFRKS 185 559
HLA-DPA1*02:02/DPB1*02:01 SNNLDSKVGGNYNYLYRLFR SNNLDSKVGGNYNYRYRLFR 498 1503
HLA-DQA1*01:02/DQB1*05:01 GGNYNYLYRLFRKSN GGNYNYRYRLFRKSN 332 1000
HLA-DQA1*01:02/DQB1*05:01 SKVGGNYNYLYRLFRKSN SKVGGNYNYRYRLFRKSN 314 944
HLA-DQA1*01:02/DQB1*05:01 VGGNYNYLYRLFRKS VGGNYNYRYRLFRKS 233 699
HLA-DPA1*03:01/DPB1*04:01 SKVGGNYNYLYRLFRKSN SKVGGNYNYRYRLFRKSN 356 1062
HLA-DPA1*03:01/DPB1*04:01 DSKVGGNYNYLYRLFRKS DSKVGGNYNYRYRLFRKS 366 1087
HLA-DQA1*01:02/DQB1*05:01 SKVGGNYNYLYRLFRK SKVGGNYNYRYRLFRK 169 501
HLA-DQA1*01:02/DQB1*05:01 LDSKVGGNYNYLYRLFRK LDSKVGGNYNYRYRLFRK 352 1027
HLA-DQA1*01:02/DQB1*05:03 SKVGGNYNYLYRLFRK SKVGGNYNYRYRLFRK 403 1175
HLA-DQA1*01:02/DQB1*05:01 DSKVGGNYNYLYRLFRKS DSKVGGNYNYRYRLFRKS 318 923
HLA-DPA1*03:01/DPB1*01:01 NLDSKVGGNYNYLYRLFRKS NLDSKVGGNYNYRYRLFRKS 191 551
HLA-DQA1*01:02/DQB1*05:03 KVGGNYNYLYRLFRKS KVGGNYNYRYRLFRKS 410 1181
HLA-DPA1*02:02/DPB1*02:01 DSKVGGNYNYLYRLFRK DSKVGGNYNYRYRLFRK 463 1330
HLA-DQA1*01:02/DQB1*05:01 KVGGNYNYLYRLFRK KVGGNYNYRYRLFRK 202 575
HLA-DRB1*11:04 SKVGGNYNYLYRLFRKSN SKVGGNYNYRYRLFRKSN 268 759
HLA-DRB1*11:01 NNLDSKVGGNYNYLYRLFRK NNLDSKVGGNYNYRYRLFRK 176 498
HLA-DPA1*02:02/DPB1*02:01 NNLDSKVGGNYNYLYRLFRK NNLDSKVGGNYNYRYRLFRK 356 999
HLA-DRB1*11:01 NLDSKVGGNYNYLYRLFRKS NLDSKVGGNYNYRYRLFRKS 118 331
HLA-DRB1*11:04 KVGGNYNYLYRLFRKSN KVGGNYNYRYRLFRKSN 70 196
HLA-DPA1*03:01/DPB1*01:01 LDSKVGGNYNYLYRLFRKS LDSKVGGNYNYRYRLFRKS 247 691
HLA-DRB1*01:01 KVGGNYNYLYRLFRK KVGGNYNYRYRLFRK 237 663
HLA-DRB1*16:01 DSKVGGNYNYLYRLFRK DSKVGGNYNYRYRLFRK 400 1110
HLA-DPA1*03:01/DPB1*04:01 KVGGNYNYLYRLFRKS KVGGNYNYRYRLFRKS 191 530
HLA-DPA1*03:01/DPB1*04:01 NLDSKVGGNYNYLYRLFRKS NLDSKVGGNYNYRYRLFRKS 174 481
HLA-DPA1*03:01/DPB1*01:01 LDSKVGGNYNYLYRLFRKSN LDSKVGGNYNYRYRLFRKSN 180 493
HLA-DPA1*02:02/DPB1*02:01 SKVGGNYNYLYRLFRK SKVGGNYNYRYRLFRK 442 1208
HLA-DQA1*01:02/DQB1*05:01 KVGGNYNYLYRLFRKSN KVGGNYNYRYRLFRKSN 224 610
HLA-DQA1*01:02/DQB1*05:01 NLDSKVGGNYNYLYRLFRK NLDSKVGGNYNYRYRLFRK 209 569
HLA-DQA1*01:02/DQB1*05:01 DSKVGGNYNYLYRLFRKSN DSKVGGNYNYRYRLFRKSN 192 520
HLA-DPA1*03:01/DPB1*01:01 DSKVGGNYNYLYRLFRKS DSKVGGNYNYRYRLFRKS 423 1140
HLA-DPA1*03:01/DPB1*01:01 SKVGGNYNYLYRLFRKSN SKVGGNYNYRYRLFRKSN 422 1133
HLA-DRB1*16:01 SKVGGNYNYLYRLFRK SKVGGNYNYRYRLFRK 416 1115
HLA-DPA1*03:01/DPB1*01:01 DSKVGGNYNYLYRLFRKSN DSKVGGNYNYRYRLFRKSN 250 668
HLA-DPA1*02:02/DPB1*05:01 NNLDSKVGGNYNYLYRLFRK NNLDSKVGGNYNYRYRLFRK 347 927
HLA-DQA1*01:02/DQB1*05:01 DSKVGGNYNYLYRLFRK DSKVGGNYNYRYRLFRK 234 625
HLA-DPA1*03:01/DPB1*04:01 LDSKVGGNYNYLYRLFRKSN LDSKVGGNYNYRYRLFRKSN 166 442
HLA-DPA1*03:01/DPB1*01:01 KVGGNYNYLYRLFRKS KVGGNYNYRYRLFRKS 232 617
HLA-DRB1*08:04 GGNYNYLYRLFRKSN GGNYNYRYRLFRKSN 141 374
HLA-DPA1*03:01/DPB1*01:01 SKVGGNYNYLYRLFRKS SKVGGNYNYRYRLFRKS 250 663
HLA-DQA1*01:02/DQB1*05:01 LDSKVGGNYNYLYRLFRKS LDSKVGGNYNYRYRLFRKS 188 496
HLA-DPA1*03:01/DPB1*04:02 LDSKVGGNYNYLYRLFRKS LDSKVGGNYNYRYRLFRKS 358 941
HLA-DRB1*11:04 GGNYNYLYRLFRKSNLKP GGNYNYRYRLFRKSNLKP 80 210
HLA-DPA1*02:02/DPB1*02:01 KVGGNYNYLYRLFRK KVGGNYNYRYRLFRK 360 937
HLA-DRB1*08:02 GGNYNYLYRLFRKSN GGNYNYRYRLFRKSN 293 762
HLA-DQA1*01:02/DQB1*05:01 DSKVGGNYNYLYRLFR DSKVGGNYNYRYRLFR 235 611
HLA-DRB1*12:02 VGGNYNYLYRLFRKSN VGGNYNYRYRLFRKSN 472 1222
HLA-DPA1*03:01/DPB1*01:01 KVGGNYNYLYRLFRKSN KVGGNYNYRYRLFRKSN 256 662
HLA-DPA1*03:01/DPB1*04:01 SKVGGNYNYLYRLFRKS SKVGGNYNYRYRLFRKS 212 546
HLA-DQA1*01:02/DQB1*05:01 SKVGGNYNYLYRLFRKS SKVGGNYNYRYRLFRKS 210 539
HLA-DQA1*01:02/DQB1*05:03 NNLDSKVGGNYNYLYRLFRK NNLDSKVGGNYNYRYRLFRK 482 1236
HLA-DPA1*03:01/DPB1*04:01 KVGGNYNYLYRLFRKSN KVGGNYNYRYRLFRKSN 214 546
HLA-DQA1*01:02/DQB1*05:01 NLDSKVGGNYNYLYRLFR NLDSKVGGNYNYRYRLFR 492 1251
HLA-DPA1*03:01/DPB1*04:02 DSKVGGNYNYLYRLFRKSN DSKVGGNYNYRYRLFRKSN 339 858
HLA-DQA1*01:02/DQB1*05:03 NLDSKVGGNYNYLYRLFRKS NLDSKVGGNYNYRYRLFRKS 443 1116
HLA-DRB1*12:02 GGNYNYLYRLFRKSN GGNYNYRYRLFRKSN 237 597
HLA-DQA1*01:02/DQB1*05:01 NNLDSKVGGNYNYLYRLFR NNLDSKVGGNYNYRYRLFR 273 687
HLA-DQA1*01:02/DQB1*05:03 LDSKVGGNYNYLYRLFRKSN LDSKVGGNYNYRYRLFRKSN 437 1099
HLA-DRB1*08:04 VGGNYNYLYRLFRKSN VGGNYNYRYRLFRKSN 305 767
HLA-DRB1*11:04 KVGGNYNYLYRLFRKSNL KVGGNYNYRYRLFRKSNL 138 346
HLA-DRB1*16:01 VGGNYNYLYRLFRKS VGGNYNYRYRLFRKS 139 348
HLA-DQA1*01:02/DQB1*05:01 SKVGGNYNYLYRLFR SKVGGNYNYRYRLFR 252 629
HLA-DQA1*01:02/DQB1*05:01 KVGGNYNYLYRLFRKSNL KVGGNYNYRYRLFRKSNL 249 621
HLA-DPA1*03:01/DPB1*04:01 VGGNYNYLYRLFRKSN VGGNYNYRYRLFRKSN 215 536
HLA-DQA1*01:02/DQB1*05:01 GGNYNYLYRLFRKSNL GGNYNYRYRLFRKSNL 225 560
HLA-DRB1*10:01 NNLDSKVGGNYNYLYRLFRK NNLDSKVGGNYNYRYRLFRK 426 1052
HLA-DPA1*03:01/DPB1*04:02 KVGGNYNYLYRLFRKS KVGGNYNYRYRLFRKS 316 779
HLA-DPA1*02:02/DPB1*01:01 LDSKVGGNYNYLYRLFRKS LDSKVGGNYNYRYRLFRKS 248 611
HLA-DQA1*01:02/DQB1*05:01 LDSKVGGNYNYLYRLFR LDSKVGGNYNYRYRLFR 311 766
HLA-DRB1*01:01 SKVGGNYNYLYRLFR SKVGGNYNYRYRLFR 366 900
HLA-DRB1*16:01 NNLDSKVGGNYNYLYRLFRK NNLDSKVGGNYNYRYRLFRK 382 933
HLA-DRB1*10:01 VGGNYNYLYRLFRKS VGGNYNYRYRLFRKS 222 539
HLA-DRB1*16:01 GGNYNYLYRLFRKSN GGNYNYRYRLFRKSN 137 332
HLA-DRB1*11:04 GGNYNYLYRLFRKSNL GGNYNYRYRLFRKSNL 43 104
HLA-DRB1*11:04 VGGNYNYLYRLFRKSNLK VGGNYNYRYRLFRKSNLK 82 197
HLA-DQA1*01:02/DQB1*05:01 LDSKVGGNYNYLYRLF LDSKVGGNYNYRYRLF 259 621
HLA-DQA1*01:02/DQB1*05:01 VGGNYNYLYRLFRKSNLK VGGNYNYRYRLFRKSNLK 304 728
HLA-DQA1*01:02/DQB1*05:01 LDSKVGGNYNYLYRL LDSKVGGNYNYRYRL 446 1065
HLA-DQA1*01:02/DQB1*05:01 NNLDSKVGGNYNYLYRLFRK NNLDSKVGGNYNYRYRLFRK 166 394
HLA-DPA1*03:01/DPB1*01:01 VGGNYNYLYRLFRKSN VGGNYNYRYRLFRKSN 268 633
HLA-DRB1*10:01 VGGNYNYLYRLFRKSN VGGNYNYRYRLFRKSN 321 758
HLA-DQA1*01:02/DQB1*05:01 VGGNYNYLYRLFRKSNL VGGNYNYRYRLFRKSNL 208 491
HLA-DQA1*01:03/DQB1*06:09 NNLDSKVGGNYNYLYRLFRK NNLDSKVGGNYNYRYRLFRK 465 1087
HLA-DPA1*03:01/DPB1*04:02 NLDSKVGGNYNYLYRLFRKS NLDSKVGGNYNYRYRLFRKS 259 605
HLA-DQA1*01:02/DQB1*05:01 DSKVGGNYNYLYRLF DSKVGGNYNYRYRLF 283 660
HLA-DRB1*11:04 DSKVGGNYNYLYRLFRKSN DSKVGGNYNYRYRLFRKSN 128 298
HLA-DRB1*08:04 KVGGNYNYLYRLFRKSN KVGGNYNYRYRLFRKSN 272 633
HLA-DQA1*01:03/DQB1*06:09 NLDSKVGGNYNYLYRLFRKS NLDSKVGGNYNYRYRLFRKS 462 1070
HLA-DQA1*01:02/DQB1*05:01 GNYNYLYRLFRKSNLK GNYNYRYRLFRKSNLK 254 588
HLA-DQA1*01:03/DQB1*06:09 LDSKVGGNYNYLYRLFRKSN LDSKVGGNYNYRYRLFRKSN 477 1104
HLA-DPA1*02:02/DPB1*01:01 DSKVGGNYNYLYRLFRKSN DSKVGGNYNYRYRLFRKSN 240 555
HLA-DRB1*10:01 GGNYNYLYRLFRKSN GGNYNYRYRLFRKSN 197 455
HLA-DQA1*01:02/DQB1*05:01 SNNLDSKVGGNYNYLYRLF SNNLDSKVGGNYNYRYRLF 324 748
HLA-DQA1*01:02/DQB1*05:01 KVGGNYNYLYRLFRKSNLK KVGGNYNYRYRLFRKSNLK 179 413
HLA-DQA1*01:02/DQB1*05:01 LDSKVGGNYNYLYRLFRKSN LDSKVGGNYNYRYRLFRKSN 150 345
HLA-DRB1*11:04 KVGGNYNYLYRLFRK KVGGNYNYRYRLFRK 64 147
HLA-DQA1*01:02/DQB1*05:01 SKVGGNYNYLYRLFRKSNL SKVGGNYNYRYRLFRKSNL 163 374
HLA-DRB1*11:04 DSKVGGNYNYLYRLFRK DSKVGGNYNYRYRLFRK 154 353
HLA-DQA1*01:02/DQB1*05:01 GGNYNYLYRLFRKSNLKP GGNYNYRYRLFRKSNLKP 401 919
HLA-DRB1*16:01 VGGNYNYLYRLFRKSN VGGNYNYRYRLFRKSN 271 618
HLA-DQA1*01:02/DQB1*05:01 NLDSKVGGNYNYLYRLF NLDSKVGGNYNYRYRLF 359 818
HLA-DQA1*01:02/DQB1*05:01 NLDSKVGGNYNYLYRLFRKS NLDSKVGGNYNYRYRLFRKS 151 344
HLA-DRB1*01:01 KVGGNYNYLYRLFRKSN KVGGNYNYRYRLFRKSN 380 865
HLA-DPA1*03:01/DPB1*02:01 DSKVGGNYNYLYRLFRKSN DSKVGGNYNYRYRLFRKSN 71 161
HLA-DRB1*10:01 KVGGNYNYLYRLFRKSN KVGGNYNYRYRLFRKSN 291 658
HLA-DPA1*02:02/DPB1*01:01 NLDSKVGGNYNYLYRLFRKS NLDSKVGGNYNYRYRLFRKS 204 461
HLA-DRB1*11:04 SKVGGNYNYLYRLFRK SKVGGNYNYRYRLFRK 171 386
HLA-DPA1*02:01/DPB1*01:01 LDSKVGGNYNYLYRLFRKS LDSKVGGNYNYRYRLFRKS 450 1014
HLA-DPA1*03:01/DPB1*02:01 SKVGGNYNYLYRLFRKSN SKVGGNYNYRYRLFRKSN 130 292
HLA-DRB1*01:01 SKVGGNYNYLYRLFRKS SKVGGNYNYRYRLFRKS 383 858
HLA-DQA1*01:02/DQB1*05:01 NLDSKVGGNYNYLYRL NLDSKVGGNYNYRYRL 451 1009
HLA-DRB1*12:02 KVGGNYNYLYRLFRKSN KVGGNYNYRYRLFRKSN 447 992
HLA-DPA1*02:01/DPB1*05:01 LDSKVGGNYNYLYRLFRKS LDSKVGGNYNYRYRLFRKS 461 1023
HLA-DRB1*15:02 KVGGNYNYLYRLFRK KVGGNYNYRYRLFRK 415 920
HLA-DRB1*01:01 VGGNYNYLYRLFRKS VGGNYNYRYRLFRKS 207 458
HLA-DQA1*01:02/DQB1*05:03 DSKVGGNYNYLYRLFRKSNL DSKVGGNYNYRYRLFRKSNL 410 906
HLA-DRB1*01:01 NNLDSKVGGNYNYLYRLFRK NNLDSKVGGNYNYRYRLFRK 393 868
HLA-DQA1*01:02/DQB1*05:03 SKVGGNYNYLYRLFRKSNLK SKVGGNYNYRYRLFRKSNLK 413 912
HLA-DQA1*01:02/DQB1*05:01 GGNYNYLYRLFRKSNLK GGNYNYRYRLFRKSNLK 275 606
HLA-DPA1*03:01/DPB1*04:02 LDSKVGGNYNYLYRLFRKSN LDSKVGGNYNYRYRLFRKSN 233 513
HLA-DRB1*11:04 NYNYLYRLFRKSNLKP NYNYRYRLFRKSNLKP 30 66
HLA-DRB1*16:01 KVGGNYNYLYRLFRKSN KVGGNYNYRYRLFRKSN 255 560
HLA-DQA1*01:02/DQB1*05:01 VGGNYNYLYRLFRKSNLKP VGGNYNYRYRLFRKSNLKP 218 478
HLA-DPA1*02:01/DPB1*01:01 DSKVGGNYNYLYRLFRKSN DSKVGGNYNYRYRLFRKSN 444 973
HLA-DRB1*01:01 GGNYNYLYRLFRKSN GGNYNYRYRLFRKSN 214 468
HLA-DPA1*02:02/DPB1*01:01 LDSKVGGNYNYLYRLFRKSN LDSKVGGNYNYRYRLFRKSN 181 395
HLA-DRB1*10:01 SKVGGNYNYLYRLFRKS SKVGGNYNYRYRLFRKS 325 709
HLA-DRB1*11:04 VGGNYNYLYRLFRKS VGGNYNYRYRLFRKS 50 109
HLA-DRB1*10:01 DSKVGGNYNYLYRLFRKSN DSKVGGNYNYRYRLFRKSN 367 799
HLA-DRB1*16:01 KVGGNYNYLYRLFRKS KVGGNYNYRYRLFRKS 293 636
HLA-DPA1*02:02/DPB1*01:01 SKVGGNYNYLYRLFRKS SKVGGNYNYRYRLFRKS 218 473
HLA-DPA1*03:01/DPB1*02:01 LDSKVGGNYNYLYRLFRKS LDSKVGGNYNYRYRLFRKS 77 167
HLA-DQA1*01:02/DQB1*05:01 SNNLDSKVGGNYNYLYRLFR SNNLDSKVGGNYNYRYRLFR 212 459
HLA-DRB1*08:02 VGGNYNYLYRLFRKS VGGNYNYRYRLFRKS 404 869
HLA-DPA1*02:02/DPB1*01:01 KVGGNYNYLYRLFRKS KVGGNYNYRYRLFRKS 220 473
HLA-DPA1*03:01/DPB1*04:02 SKVGGNYNYLYRLFRKS SKVGGNYNYRYRLFRKS 350 752
HLA-DQA1*01:03/DQB1*06:09 DSKVGGNYNYLYRLFRKSNL DSKVGGNYNYRYRLFRKSNL 427 917
HLA-DRB1*11:04 VGGNYNYLYRLFRKSNL VGGNYNYRYRLFRKSNL 41 88
HLA-DRB1*01:01 KVGGNYNYLYRLFRKS KVGGNYNYRYRLFRKS 462 991
HLA-DQA1*01:02/DQB1*05:03 KVGGNYNYLYRLFRKSNLKP KVGGNYNYRYRLFRKSNLKP 434 930
HLA-DRB1*11:04 GNYNYLYRLFRKSNLKPF GNYNYRYRLFRKSNLKPF 71 152
HLA-DQA1*01:02/DQB1*05:01 GNYNYLYRLFRKSNL GNYNYRYRLFRKSNL 268 573
HLA-DRB1*11:04 GNYNYLYRLFRKSNLK GNYNYRYRLFRKSNLK 29 62
HLA-DPA1*03:01/DPB1*04:02 VGGNYNYLYRLFRKSN VGGNYNYRYRLFRKSN 345 736
HLA-DPA1*04:01/DPB1*04:01 LDSKVGGNYNYLYRLFRKS LDSKVGGNYNYRYRLFRKS 274 583
HLA-DRB1*10:01 KVGGNYNYLYRLFRKS KVGGNYNYRYRLFRKS 356 756
HLA-DRB1*16:01 SKVGGNYNYLYRLFRKS SKVGGNYNYRYRLFRKS 279 592
HLA-DPA1*03:01/DPB1*01:01 VGGNYNYLYRLFRKS VGGNYNYRYRLFRKS 273 579
HLA-DRB1*11:04 GNYNYLYRLFRKSNLKP GNYNYRYRLFRKSNLKP 25 53
HLA-DRB1*10:01 LDSKVGGNYNYLYRLFRKS LDSKVGGNYNYRYRLFRKS 419 887
HLA-DPA1*02:02/DPB1*05:01 LDSKVGGNYNYLYRLFRKS LDSKVGGNYNYRYRLFRKS 294 622
HLA-DPA1*02:01/DPB1*05:01 SKVGGNYNYLYRLFRKS SKVGGNYNYRYRLFRKS 371 782
HLA-DQA1*01:02/DQB1*05:01 SKVGGNYNYLYRLFRKSNLK SKVGGNYNYRYRLFRKSNLK 140 295
HLA-DQA1*01:02/DQB1*05:01 KVGGNYNYLYRLFRKSNLKP KVGGNYNYRYRLFRKSNLKP 154 324
HLA-DPA1*02:01/DPB1*05:01 KVGGNYNYLYRLFRKS KVGGNYNYRYRLFRKS 388 815
HLA-DPA1*03:01/DPB1*02:01 DSKVGGNYNYLYRLFRKS DSKVGGNYNYRYRLFRKS 143 300
HLA-DPA1*03:01/DPB1*04:01 VGGNYNYLYRLFRKS VGGNYNYRYRLFRKS 198 415
HLA-DPA1*02:02/DPB1*01:01 DSKVGGNYNYLYRLFRKS DSKVGGNYNYRYRLFRKS 418 876
HLA-DPA1*03:01/DPB1*04:02 VGGNYNYLYRLFRKS VGGNYNYRYRLFRKS 295 618
HLA-DPA1*02:01/DPB1*05:01 DSKVGGNYNYLYRLFRKSN DSKVGGNYNYRYRLFRKSN 423 885
HLA-DRB1*16:01 LDSKVGGNYNYLYRLFRKSN LDSKVGGNYNYRYRLFRKSN 198 414
HLA-DQA1*01:02/DQB1*05:01 GNYNYLYRLFRKSNLKP GNYNYRYRLFRKSNLKP 297 618
HLA-DPA1*02:02/DPB1*01:01 SKVGGNYNYLYRLFRKSN SKVGGNYNYRYRLFRKSN 384 799
HLA-DRB1*08:04 KVGGNYNYLYRLFRK KVGGNYNYRYRLFRK 311 646
HLA-DQA1*01:03/DQB1*06:09 SKVGGNYNYLYRLFRKSNLK SKVGGNYNYRYRLFRKSNLK 444 919
HLA-DPA1*02:01/DPB1*05:01 VGGNYNYLYRLFRKS VGGNYNYRYRLFRKS 304 629
HLA-DRB1*11:04 NYNYLYRLFRKSNLKPFE NYNYRYRLFRKSNLKPFE 75 155
HLA-DRB1*11:04 KVGGNYNYLYRLFRKS KVGGNYNYRYRLFRKS 129 266
HLA-DPA1*02:02/DPB1*01:01 KVGGNYNYLYRLFRKSN KVGGNYNYRYRLFRKSN 216 445
HLA-DRB1*01:01 VGGNYNYLYRLFRKSN VGGNYNYRYRLFRKSN 490 1009
HLA-DRB1*01:01 DSKVGGNYNYLYRLFRKSN DSKVGGNYNYRYRLFRKSN 484 996
HLA-DPA1*03:01/DPB1*04:02 KVGGNYNYLYRLFRKSN KVGGNYNYRYRLFRKSN 336 690
HLA-DQA1*01:02/DQB1*05:01 DSKVGGNYNYLYRLFRKSNL DSKVGGNYNYRYRLFRKSNL 134 275
HLA-DRB1*08:04 VGGNYNYLYRLFRKS VGGNYNYRYRLFRKS 212 435
HLA-DPA1*02:02/DPB1*05:01 KVGGNYNYLYRLFRKS KVGGNYNYRYRLFRKS 240 492
HLA-DPA1*03:01/DPB1*02:01 KVGGNYNYLYRLFRKSN KVGGNYNYRYRLFRKSN 69 141
HLA-DRB1*16:01 DSKVGGNYNYLYRLFRKSN DSKVGGNYNYRYRLFRKSN 354 721
HLA-DQA1*01:02/DQB1*05:01 NSNNLDSKVGGNYNYLYRLF NSNNLDSKVGGNYNYRYRLF 247 503
HLA-DPA1*02:01/DPB1*01:01 LDSKVGGNYNYLYRLFRKSN LDSKVGGNYNYRYRLFRKSN 325 661
HLA-DPA1*02:01/DPB1*01:01 NLDSKVGGNYNYLYRLFRKS NLDSKVGGNYNYRYRLFRKS 360 732
HLA-DPA1*02:02/DPB1*05:01 SKVGGNYNYLYRLFRKS SKVGGNYNYRYRLFRKS 224 454
HLA-DPA1*02:02/DPB1*05:01 DSKVGGNYNYLYRLFRKSN DSKVGGNYNYRYRLFRKSN 265 537
HLA-DRB1*16:01 NLDSKVGGNYNYLYRLFRKS NLDSKVGGNYNYRYRLFRKS 222 449
HLA-DRB1*11:04 LDSKVGGNYNYLYRLFR LDSKVGGNYNYRYRLFR 480 969
HLA-DRB1*16:01 LDSKVGGNYNYLYRLFRKS LDSKVGGNYNYRYRLFRKS 381 768
HLA-DPA1*02:02/DPB1*05:01 VGGNYNYLYRLFRKS VGGNYNYRYRLFRKS 198 399
HLA-DPA1*02:01/DPB1*05:01 NLDSKVGGNYNYLYRLFRKS NLDSKVGGNYNYRYRLFRKS 306 616
HLA-DPA1*04:01/DPB1*04:01 DSKVGGNYNYLYRLFRKSN DSKVGGNYNYRYRLFRKSN 265 533
HLA-DRB1*10:01 LDSKVGGNYNYLYRLFRKSN LDSKVGGNYNYRYRLFRKSN 241 483
HLA-DRB1*11:04 GNYNYLYRLFRKSNL GNYNYRYRLFRKSNL 21 42
HLA-DPA1*02:02/DPB1*05:01 GGNYNYLYRLFRKSN GGNYNYRYRLFRKSN 184 368
HLA-DRB1*11:04 DSKVGGNYNYLYRLFRKS DSKVGGNYNYRYRLFRKS 440 880

T478K

Reference  YRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGV
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Mutated    YRLFRKSNLKPFERDISTEIYQAGSKPCNGVEGFNCYFPLQSYGFQPTNGV

Export table to csv 
Allele Reference peptide Mutated peptide Reference affinity (IC50, nM) Mutated affinity (IC50, nM)
HLA-DQA1*05:01/DQB1*03:01 DISTEIYQAGSTPCN DISTEIYQAGSKPCN 251 990
HLA-DQA1*05:01/DQB1*03:01 ERDISTEIYQAGSTPCN ERDISTEIYQAGSKPCN 490 1575
HLA-DQA1*05:01/DQB1*03:01 RDISTEIYQAGSTPCN RDISTEIYQAGSKPCN 357 1082
HLA-DRB1*10:01 TEIYQAGSTPCNGVE TEIYQAGSKPCNGVE 404 1193
HLA-DRB1*10:01 STEIYQAGSTPCNGV STEIYQAGSKPCNGV 354 993
HLA-DQA1*02:01/DQB1*03:03 DISTEIYQAGSTPCNGVEGF DISTEIYQAGSKPCNGVEGF 498 1339
HLA-DRB1*10:01 STEIYQAGSTPCNGVEGFNC STEIYQAGSKPCNGVEGFNC 494 1264
HLA-DRB1*10:01 ISTEIYQAGSTPCNGVEGFN ISTEIYQAGSKPCNGVEGFN 442 1096
HLA-DQA1*05:01/DQB1*03:01 IYQAGSTPCNGVEGFN IYQAGSKPCNGVEGFN 196 483
HLA-DQA1*05:01/DQB1*03:01 FERDISTEIYQAGSTPCNG FERDISTEIYQAGSKPCNG 424 1031
HLA-DQA1*05:01/DQB1*03:01 TEIYQAGSTPCNGVEGF TEIYQAGSKPCNGVEGF 158 384
HLA-DQA1*02:01/DQB1*03:03 RDISTEIYQAGSTPCNGVEG RDISTEIYQAGSKPCNGVEG 459 1112
HLA-DQA1*05:01/DQB1*03:01 ISTEIYQAGSTPCNG ISTEIYQAGSKPCNG 150 363
HLA-DQA1*05:01/DQB1*03:01 TEIYQAGSTPCNGVEGFNC TEIYQAGSKPCNGVEGFNC 256 619
HLA-DQA1*05:01/DQB1*03:01 STEIYQAGSTPCNGVEGFN STEIYQAGSKPCNGVEGFN 235 567
HLA-DQA1*05:01/DQB1*03:01 STEIYQAGSTPCNGVEG STEIYQAGSKPCNGVEG 148 357
HLA-DQA1*05:01/DQB1*03:01 EIYQAGSTPCNGVEGF EIYQAGSKPCNGVEGF 139 334
HLA-DQA1*05:01/DQB1*03:01 ISTEIYQAGSTPCNGVEGF ISTEIYQAGSKPCNGVEGF 225 540
HLA-DQA1*05:01/DQB1*03:01 RDISTEIYQAGSTPCNG RDISTEIYQAGSKPCNG 290 693
HLA-DQA1*05:01/DQB1*03:01 TEIYQAGSTPCNGVEGFNCY TEIYQAGSKPCNGVEGFNCY 185 442
HLA-DRB1*10:01 DISTEIYQAGSTPCNGVEGF DISTEIYQAGSKPCNGVEGF 401 958
HLA-DQA1*05:01/DQB1*03:01 DISTEIYQAGSTPCNGVEG DISTEIYQAGSKPCNGVEG 225 537
HLA-DQA1*06:01/DQB1*03:01 STEIYQAGSTPCNGVE STEIYQAGSKPCNGVE 254 606
HLA-DQA1*05:01/DQB1*03:01 STEIYQAGSTPCNGVEGFNC STEIYQAGSKPCNGVEGFNC 170 404
HLA-DQA1*06:01/DQB1*03:01 EIYQAGSTPCNGVEGF EIYQAGSKPCNGVEGF 314 746
HLA-DQA1*06:01/DQB1*03:01 TEIYQAGSTPCNGVEGF TEIYQAGSKPCNGVEGF 387 919
HLA-DQA1*06:01/DQB1*03:01 TEIYQAGSTPCNGVEG TEIYQAGSKPCNGVEG 276 653
HLA-DQA1*05:01/DQB1*03:01 DISTEIYQAGSTPCNGVE DISTEIYQAGSKPCNGVE 396 936
HLA-DQA1*05:01/DQB1*03:01 TEIYQAGSTPCNGVEGFN TEIYQAGSKPCNGVEGFN 440 1034
HLA-DQA1*05:01/DQB1*03:01 STEIYQAGSTPCNGVEGF STEIYQAGSKPCNGVEGF 406 954
HLA-DQA1*06:01/DQB1*03:01 STEIYQAGSTPCNGVEG STEIYQAGSKPCNGVEG 365 857
HLA-DQA1*06:01/DQB1*03:01 IYQAGSTPCNGVEGFN IYQAGSKPCNGVEGFN 440 1032
HLA-DQA1*05:01/DQB1*03:01 RDISTEIYQAGSTPCNGVE RDISTEIYQAGSKPCNGVE 238 556
HLA-DQA1*05:01/DQB1*03:01 TEIYQAGSTPCNGVEG TEIYQAGSKPCNGVEG 120 280
HLA-DQA1*05:01/DQB1*03:01 ISTEIYQAGSTPCNGVEG ISTEIYQAGSKPCNGVEG 395 920
HLA-DQA1*06:01/DQB1*03:01 IYQAGSTPCNGVEGF IYQAGSKPCNGVEGF 359 836
HLA-DQA1*05:01/DQB1*03:01 IYQAGSTPCNGVEGF IYQAGSKPCNGVEGF 137 319
HLA-DQA1*05:01/DQB1*03:01 EIYQAGSTPCNGVEGFN EIYQAGSKPCNGVEGFN 191 444
HLA-DQA1*06:01/DQB1*03:01 EIYQAGSTPCNGVEGFN EIYQAGSKPCNGVEGFN 449 1043
HLA-DQA1*05:01/DQB1*03:01 EIYQAGSTPCNGVEGFNCY EIYQAGSKPCNGVEGFNCY 310 719
HLA-DQA1*05:01/DQB1*03:01 EIYQAGSTPCNGVEG EIYQAGSKPCNGVEG 99 229
HLA-DQA1*05:01/DQB1*03:01 RDISTEIYQAGSTPCNGV RDISTEIYQAGSKPCNGV 428 990
HLA-DQA1*04:01/DQB1*03:01 TEIYQAGSTPCNGVE TEIYQAGSKPCNGVE 499 1148
HLA-DQA1*05:01/DQB1*03:01 ERDISTEIYQAGSTPCNGV ERDISTEIYQAGSKPCNGV 270 620
HLA-DQA1*06:01/DQB1*03:01 EIYQAGSTPCNGVEG EIYQAGSKPCNGVEG 270 620
HLA-DQA1*05:01/DQB1*03:01 ISTEIYQAGSTPCNGVE ISTEIYQAGSKPCNGVE 149 342
HLA-DQA1*06:01/DQB1*03:01 TEIYQAGSTPCNGVE TEIYQAGSKPCNGVE 238 544
HLA-DQA1*06:01/DQB1*03:01 ISTEIYQAGSTPCNGVE ISTEIYQAGSKPCNGVE 353 806
HLA-DQA1*05:01/DQB1*03:01 IYQAGSTPCNGVEGFNC IYQAGSKPCNGVEGFNC 275 627
HLA-DQA1*06:01/DQB1*03:01 STEIYQAGSTPCNGVEGFN STEIYQAGSKPCNGVEGFN 486 1106
HLA-DQA1*05:01/DQB1*03:01 EIYQAGSTPCNGVEGFNCYF EIYQAGSKPCNGVEGFNCYF 228 517
HLA-DQA1*05:01/DQB1*03:01 TEIYQAGSTPCNGVE TEIYQAGSKPCNGVE 86 195
HLA-DQA1*05:01/DQB1*03:01 ISTEIYQAGSTPCNGVEGFN ISTEIYQAGSKPCNGVEGFN 163 369
HLA-DQA1*06:01/DQB1*03:01 STEIYQAGSTPCNGV STEIYQAGSKPCNGV 234 529
HLA-DQA1*05:01/DQB1*03:01 DISTEIYQAGSTPCNG DISTEIYQAGSKPCNG 210 473
HLA-DQA1*04:01/DQB1*03:01 TEIYQAGSTPCNGVEG TEIYQAGSKPCNGVEG 453 1018
HLA-DQA1*05:01/DQB1*03:01 DISTEIYQAGSTPCNGVEGF DISTEIYQAGSKPCNGVEGF 160 358
HLA-DQA1*06:01/DQB1*03:01 TEIYQAGSTPCNGVEGFNCY TEIYQAGSKPCNGVEGFNCY 407 910
HLA-DQA1*02:01/DQB1*03:03 ERDISTEIYQAGSTPCNGVE ERDISTEIYQAGSKPCNGVE 420 936
HLA-DQA1*06:01/DQB1*03:01 STEIYQAGSTPCNGVEGFNC STEIYQAGSKPCNGVEGFNC 372 829
HLA-DQA1*05:01/DQB1*03:01 DISTEIYQAGSTPCNGV DISTEIYQAGSKPCNGV 168 373
HLA-DQA1*06:01/DQB1*03:01 ISTEIYQAGSTPCNGV ISTEIYQAGSKPCNGV 264 586
HLA-DQA1*06:01/DQB1*03:01 ISTEIYQAGSTPCNGVEGF ISTEIYQAGSKPCNGVEGF 469 1040
HLA-DQA1*05:01/DQB1*03:01 STEIYQAGSTPCNGVE STEIYQAGSKPCNGVE 117 259
HLA-DQA1*06:01/DQB1*03:01 ISTEIYQAGSTPCNG ISTEIYQAGSKPCNG 375 827
HLA-DQA1*04:01/DQB1*03:01 STEIYQAGSTPCNGVE STEIYQAGSKPCNGVE 438 964
HLA-DQA1*05:01/DQB1*03:01 RDISTEIYQAGSTPCNGVEG RDISTEIYQAGSKPCNGVEG 161 353
HLA-DQA1*05:01/DQB1*03:01 YQAGSTPCNGVEGFN YQAGSKPCNGVEGFN 302 661
HLA-DQA1*05:01/DQB1*03:01 STEIYQAGSTPCNGV STEIYQAGSKPCNGV 91 198
HLA-DQA1*05:01/DQB1*03:01 IYQAGSTPCNGVEGFNCYF IYQAGSKPCNGVEGFNCYF 471 1024
HLA-DQA1*05:01/DQB1*03:01 PFERDISTEIYQAGSTPCNG PFERDISTEIYQAGSKPCNG 323 698
HLA-DQA1*06:01/DQB1*03:01 ISTEIYQAGSTPCNGVEGFN ISTEIYQAGSKPCNGVEGFN 351 756
HLA-DQA1*06:01/DQB1*03:01 DISTEIYQAGSTPCNGVEG DISTEIYQAGSKPCNGVEG 465 1000
HLA-DQA1*05:01/DQB1*03:01 YQAGSTPCNGVEGFNC YQAGSKPCNGVEGFNC 457 980
HLA-DQA1*05:01/DQB1*03:01 ISTEIYQAGSTPCNGV ISTEIYQAGSKPCNGV 125 268
HLA-DQA1*06:01/DQB1*03:01 DISTEIYQAGSTPCNGV DISTEIYQAGSKPCNGV 367 782
HLA-DQA1*05:01/DQB1*03:01 ERDISTEIYQAGSTPCNGVE ERDISTEIYQAGSKPCNGVE 175 372
HLA-DRB1*10:01 RDISTEIYQAGSTPCNGVEG RDISTEIYQAGSKPCNGVEG 365 768
HLA-DQA1*05:01/DQB1*03:01 IYQAGSTPCNGVEGFNCYFP IYQAGSKPCNGVEGFNCYFP 363 761
HLA-DQA1*06:01/DQB1*03:01 EIYQAGSTPCNGVEGFNCYF EIYQAGSKPCNGVEGFNCYF 480 1003
HLA-DQA1*06:01/DQB1*03:01 DISTEIYQAGSTPCNG DISTEIYQAGSKPCNG 401 832
HLA-DQA1*06:01/DQB1*03:01 DISTEIYQAGSTPCNGVEGF DISTEIYQAGSKPCNGVEGF 341 704
HLA-DQA1*06:01/DQB1*03:01 RDISTEIYQAGSTPCNGVE RDISTEIYQAGSKPCNGVE 458 945
HLA-DQA1*05:01/DQB1*03:01 FERDISTEIYQAGSTPCNGV FERDISTEIYQAGSKPCNGV 206 425
HLA-DQA1*06:01/DQB1*03:01 ERDISTEIYQAGSTPCNGV ERDISTEIYQAGSKPCNGV 484 998
HLA-DRB1*10:01 ERDISTEIYQAGSTPCNGVE ERDISTEIYQAGSKPCNGVE 350 719
HLA-DQA1*04:01/DQB1*03:01 ISTEIYQAGSTPCNGV ISTEIYQAGSKPCNGV 495 1008

D614G

Reference  PCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTG
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Mutated    PCSFGGVSVITPGTNTSNQVAVLYQGVNCTEVPVAIHADQLTPTWRVYSTG

Export table to csv 
Allele Reference peptide Mutated peptide Reference affinity (IC50, nM) Mutated affinity (IC50, nM)
HLA-DQA1*01:02/DQB1*06:02 SNQVAVLYQDVNCTE SNQVAVLYQGVNCTE 533 192
HLA-DRB1*01:01 AVLYQDVNCTEVPVA AVLYQGVNCTEVPVA 521 192
HLA-DQA1*01:02/DQB1*06:02 TSNQVAVLYQDVNCTE TSNQVAVLYQGVNCTE 328 123
HLA-DQA1*01:02/DQB1*06:02 SNQVAVLYQDVNCTEVP SNQVAVLYQGVNCTEVP 889 335
HLA-DQA1*01:02/DQB1*06:02 NTSNQVAVLYQDVNCTE NTSNQVAVLYQGVNCTE 281 107
HLA-DQA1*01:02/DQB1*06:02 SNQVAVLYQDVNCTEV SNQVAVLYQGVNCTEV 677 258
HLA-DQA1*01:02/DQB1*06:02 TSNQVAVLYQDVNCT TSNQVAVLYQGVNCT 243 93
HLA-DQA1*01:02/DQB1*06:02 NTSNQVAVLYQDVNCT NTSNQVAVLYQGVNCT 227 87
HLA-DQA1*01:02/DQB1*06:02 TNTSNQVAVLYQDVN TNTSNQVAVLYQGVN 130 50
HLA-DQA1*01:02/DQB1*06:02 TSNQVAVLYQDVNCTEV TSNQVAVLYQGVNCTEV 403 155
HLA-DQA1*01:02/DQB1*06:02 GTNTSNQVAVLYQDV GTNTSNQVAVLYQGV 136 53
HLA-DQA1*01:02/DQB1*06:02 PGTNTSNQVAVLYQD PGTNTSNQVAVLYQG 228 89
HLA-DQA1*01:02/DQB1*06:02 PGTNTSNQVAVLYQDVN PGTNTSNQVAVLYQGVN 176 69
HLA-DQA1*01:02/DQB1*06:02 NTSNQVAVLYQDVNC NTSNQVAVLYQGVNC 181 71
HLA-DQA1*01:02/DQB1*06:02 GTNTSNQVAVLYQDVN GTNTSNQVAVLYQGVN 150 59
HLA-DQA1*01:02/DQB1*06:02 PGTNTSNQVAVLYQDV PGTNTSNQVAVLYQGV 167 66
HLA-DQA1*01:02/DQB1*06:02 TPGTNTSNQVAVLYQDV TPGTNTSNQVAVLYQGV 200 80
HLA-DQA1*01:02/DQB1*06:02 TPGTNTSNQVAVLYQD TPGTNTSNQVAVLYQG 276 112
HLA-DRB1*01:01 VAVLYQDVNCTEVPV VAVLYQGVNCTEVPV 347 141
HLA-DQA1*01:02/DQB1*06:02 NTSNQVAVLYQDVNCTEV NTSNQVAVLYQGVNCTEV 639 263
HLA-DQA1*01:03/DQB1*06:02 GTNTSNQVAVLYQDVN GTNTSNQVAVLYQGVN 413 170
HLA-DQA1*01:02/DQB1*06:02 TPGTNTSNQVAVLYQDVN TPGTNTSNQVAVLYQGVN 376 155
HLA-DQA1*01:02/DQB1*06:02 ITPGTNTSNQVAVLYQD ITPGTNTSNQVAVLYQG 339 140
HLA-DRB1*01:01 QVAVLYQDVNCTEVPVA QVAVLYQGVNCTEVPVA 814 340
HLA-DRB1*01:01 VLYQDVNCTEVPVAI VLYQGVNCTEVPVAI 867 365
HLA-DQA1*01:02/DQB1*06:02 ITPGTNTSNQVAVLYQDV ITPGTNTSNQVAVLYQGV 435 184
HLA-DQA1*01:02/DQB1*06:02 ITPGTNTSNQVAVLYQDVN ITPGTNTSNQVAVLYQGVN 229 97
HLA-DQA1*01:03/DQB1*06:02 SNQVAVLYQDVNCTE SNQVAVLYQGVNCTE 960 408
HLA-DRB1*01:01 NQVAVLYQDVNCTEVPV NQVAVLYQGVNCTEVPV 799 340
HLA-DQA1*01:02/DQB1*06:02 TNTSNQVAVLYQDVNC TNTSNQVAVLYQGVNC 176 75
HLA-DQA1*01:02/DQB1*06:02 TNTSNQVAVLYQDVNCT TNTSNQVAVLYQGVNCT 211 90
HLA-DRB1*01:01 VAVLYQDVNCTEVPVAI VAVLYQGVNCTEVPVAI 996 428
HLA-DQA1*01:03/DQB1*06:02 TNTSNQVAVLYQDVN TNTSNQVAVLYQGVN 292 126
HLA-DQA1*01:03/DQB1*06:02 NTSNQVAVLYQDVNC NTSNQVAVLYQGVNC 417 181
HLA-DRB1*01:01 SNQVAVLYQDVNCTEVP SNQVAVLYQGVNCTEVP 852 370
HLA-DQA1*01:03/DQB1*06:02 GTNTSNQVAVLYQDV GTNTSNQVAVLYQGV 312 136
HLA-DRB1*01:01 TSNQVAVLYQDVNCT TSNQVAVLYQGVNCT 699 305
HLA-DQA1*01:02/DQB1*06:02 GTNTSNQVAVLYQDVNC GTNTSNQVAVLYQGVNC 197 86
HLA-DQA1*01:02/DQB1*06:02 NTSNQVAVLYQDVNCTEVP NTSNQVAVLYQGVNCTEVP 412 180
HLA-DQA1*01:02/DQB1*06:02 TSNQVAVLYQDVNCTEVP TSNQVAVLYQGVNCTEVP 908 399
HLA-DQA1*01:03/DQB1*06:02 PGTNTSNQVAVLYQDV PGTNTSNQVAVLYQGV 450 198
HLA-DRB1*01:01 QVAVLYQDVNCTEVP QVAVLYQGVNCTEVP 285 126
HLA-DQA1*01:03/DQB1*06:02 TSNQVAVLYQDVNCT TSNQVAVLYQGVNCT 530 235
HLA-DQA1*01:02/DQB1*06:02 VITPGTNTSNQVAVLYQDVN VITPGTNTSNQVAVLYQGVN 189 84
HLA-DQA1*01:02/DQB1*06:02 VITPGTNTSNQVAVLYQDV VITPGTNTSNQVAVLYQGV 270 121
HLA-DRB1*01:01 SNQVAVLYQDVNCTE SNQVAVLYQGVNCTE 450 202
HLA-DQA1*01:03/DQB1*06:02 NTSNQVAVLYQDVNCT NTSNQVAVLYQGVNCT 597 268
HLA-DQA1*01:03/DQB1*06:02 TSNQVAVLYQDVNCTE TSNQVAVLYQGVNCTE 838 380
HLA-DRB1*01:01 VAVLYQDVNCTEVPVA VAVLYQGVNCTEVPVA 1017 462
HLA-DRB1*01:01 TSNQVAVLYQDVNCTEV TSNQVAVLYQGVNCTEV 801 365
HLA-DRB1*10:01 VLYQDVNCTEVPVAI VLYQGVNCTEVPVAI 910 416
HLA-DRB1*01:01 SNQVAVLYQDVNCTEVPVA SNQVAVLYQGVNCTEVPVA 979 449
HLA-DQA1*01:02/DQB1*06:02 NTSNQVAVLYQDVNCTEVPV NTSNQVAVLYQGVNCTEVPV 365 168
HLA-DQA1*01:03/DQB1*06:02 PGTNTSNQVAVLYQDVN PGTNTSNQVAVLYQGVN 447 206
HLA-DQA1*01:02/DQB1*06:02 PGTNTSNQVAVLYQDVNC PGTNTSNQVAVLYQGVNC 425 196
HLA-DQA1*01:03/DQB1*06:02 PGTNTSNQVAVLYQD PGTNTSNQVAVLYQG 471 218
HLA-DQA1*01:02/DQB1*06:02 TNTSNQVAVLYQDVNCTE TNTSNQVAVLYQGVNCTE 477 221
HLA-DRB1*01:01 QVAVLYQDVNCTEVPV QVAVLYQGVNCTEVPV 855 397
HLA-DRB1*01:01 NQVAVLYQDVNCTEV NQVAVLYQGVNCTEV 253 118
HLA-DRB1*01:01 TSNQVAVLYQDVNCTEVPVA TSNQVAVLYQGVNCTEVPVA 488 228
HLA-DQA1*01:02/DQB1*06:02 GTNTSNQVAVLYQDVNCT GTNTSNQVAVLYQGVNCT 436 204
HLA-DRB1*01:01 NQVAVLYQDVNCTEVP NQVAVLYQGVNCTEVP 887 416
HLA-DRB1*01:01 NQVAVLYQDVNCTEVPVAI NQVAVLYQGVNCTEVPVAI 991 467
HLA-DRB1*01:01 TSNQVAVLYQDVNCTEVPV TSNQVAVLYQGVNCTEVPV 984 467
HLA-DQA1*01:03/DQB1*06:02 TNTSNQVAVLYQDVNC TNTSNQVAVLYQGVNC 485 231
HLA-DQA1*01:02/DQB1*06:02 TSNQVAVLYQDVNCTEVPV TSNQVAVLYQGVNCTEVPV 641 306
HLA-DRB1*01:01 QVAVLYQDVNCTEVPVAIH QVAVLYQGVNCTEVPVAIH 1021 488
HLA-DPA1*03:01/DPB1*04:01 GTNTSNQVAVLYQDV GTNTSNQVAVLYQGV 307 635
HLA-DRB1*01:01 SNQVAVLYQDVNCTEV SNQVAVLYQGVNCTEV 850 411
HLA-DRB1*01:01 NTSNQVAVLYQDVNCTEVPV NTSNQVAVLYQGVNCTEVPV 502 243
HLA-DRB1*01:01 SNQVAVLYQDVNCTEVPVAI SNQVAVLYQGVNCTEVPVAI 481 235
HLA-DQA1*01:02/DQB1*06:02 SVITPGTNTSNQVAVLYQDV SVITPGTNTSNQVAVLYQGV 231 113
HLA-DRB1*01:01 NQVAVLYQDVNCTEVPVAIH NQVAVLYQGVNCTEVPVAIH 483 237
HLA-DQA1*01:03/DQB1*06:02 TSNQVAVLYQDVNCTEV TSNQVAVLYQGVNCTEV 936 460
HLA-DQA1*01:03/DQB1*06:02 TPGTNTSNQVAVLYQDV TPGTNTSNQVAVLYQGV 493 243
HLA-DQA1*01:02/DQB1*06:02 TNTSNQVAVLYQDVNCTEV TNTSNQVAVLYQGVNCTEV 298 147
HLA-DQA1*01:02/DQB1*06:02 TPGTNTSNQVAVLYQDVNC TPGTNTSNQVAVLYQGVNC 254 126
HLA-DQA1*01:02/DQB1*06:02 VITPGTNTSNQVAVLYQD VITPGTNTSNQVAVLYQG 681 338
HLA-DRB1*01:01 TNTSNQVAVLYQDVNCTEVP TNTSNQVAVLYQGVNCTEVP 523 260
HLA-DRB1*01:01 QVAVLYQDVNCTEVPVAIHA QVAVLYQGVNCTEVPVAIHA 502 251

P681R

Reference  VNNSYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVA
           ||||||||||||||||||||||||| |||||||||||||||||||||||||
Mutated    VNNSYECDIPIGAGICASYQTQTNSRRRARSVASQSIIAYTMSLGAENSVA

Export table to csv 
Allele Reference peptide Mutated peptide Reference affinity (IC50, nM) Mutated affinity (IC50, nM)
HLA-DPA1*01:03/DPB1*03:01 TQTNSPRRARSVASQ TQTNSRRRARSVASQ 2758 405
HLA-DQA1*05:01/DQB1*03:01 QTQTNSPRRARSVASQ QTQTNSRRRARSVASQ 202 1295
HLA-DQA1*05:01/DQB1*03:01 TQTNSPRRARSVASQ TQTNSRRRARSVASQ 168 1012
HLA-DQA1*05:01/DQB1*03:01 QTNSPRRARSVASQS QTNSRRRARSVASQS 134 749
HLA-DPA1*01:03/DPB1*03:01 CASYQTQTNSPRRARSVASQ CASYQTQTNSRRRARSVASQ 1810 324
HLA-DQA1*05:01/DQB1*03:01 TQTNSPRRARSVASQS TQTNSRRRARSVASQS 168 916
HLA-DQA1*05:01/DQB1*03:01 YQTQTNSPRRARSVAS YQTQTNSRRRARSVAS 288 1480
HLA-DQA1*02:01/DQB1*03:03 YQTQTNSPRRARSVAS YQTQTNSRRRARSVAS 465 2360
HLA-DRB1*11:04 YQTQTNSPRRARSVA YQTQTNSRRRARSVA 912 182
HLA-DQA1*05:01/DQB1*03:01 QTQTNSPRRARSVAS QTQTNSRRRARSVAS 247 1228
HLA-DQA1*05:01/DQB1*03:01 YQTQTNSPRRARSVASQ YQTQTNSRRRARSVASQ 290 1438
HLA-DRB1*11:04 QTQTNSPRRARSVAS QTQTNSRRRARSVAS 1281 259
HLA-DQA1*06:01/DQB1*03:01 QTQTNSPRRARSVASQ QTQTNSRRRARSVASQ 425 2059
HLA-DRB1*11:04 SYQTQTNSPRRARSV SYQTQTNSRRRARSV 903 189
HLA-DQA1*06:01/DQB1*03:01 YQTQTNSPRRARSVAS YQTQTNSRRRARSVAS 491 2290
HLA-DQA1*06:01/DQB1*03:01 TQTNSPRRARSVASQ TQTNSRRRARSVASQ 413 1922
HLA-DQA1*06:01/DQB1*03:01 QTQTNSPRRARSVAS QTQTNSRRRARSVAS 496 2289
HLA-DQA1*05:01/DQB1*03:01 QTQTNSPRRARSVASQS QTQTNSRRRARSVASQS 237 1075
HLA-DQA1*02:01/DQB1*03:03 QTQTNSPRRARSVASQ QTQTNSRRRARSVASQ 469 2105
HLA-DQA1*05:01/DQB1*03:01 ASYQTQTNSPRRARSVASQ ASYQTQTNSRRRARSVASQ 446 1945
HLA-DRB1*11:04 ASYQTQTNSPRRARSVA ASYQTQTNSRRRARSVA 1434 330
HLA-DRB1*11:04 ASYQTQTNSPRRARS ASYQTQTNSRRRARS 1113 259
HLA-DRB1*11:04 CASYQTQTNSPRRARSV CASYQTQTNSRRRARSV 1616 380
HLA-DQA1*05:01/DQB1*03:01 SYQTQTNSPRRARSVAS SYQTQTNSRRRARSVAS 403 1709
HLA-DRB1*11:01 YQTQTNSPRRARSVA YQTQTNSRRRARSVA 1740 414
HLA-DRB1*11:04 SYQTQTNSPRRARSVA SYQTQTNSRRRARSVA 1916 457
HLA-DRB1*11:04 GICASYQTQTNSPRRARSVA GICASYQTQTNSRRRARSVA 1241 299
HLA-DQA1*05:01/DQB1*03:01 SYQTQTNSPRRARSVASQS SYQTQTNSRRRARSVASQS 365 1486
HLA-DRB1*11:04 SYQTQTNSPRRARSVAS SYQTQTNSRRRARSVAS 1392 345
HLA-DRB1*11:04 ICASYQTQTNSPRRARSVAS ICASYQTQTNSRRRARSVAS 1131 282
HLA-DQA1*05:01/DQB1*03:01 TNSPRRARSVASQSI TNSRRRARSVASQSI 107 429
HLA-DRB1*11:04 AGICASYQTQTNSPRRARSV AGICASYQTQTNSRRRARSV 1419 357
HLA-DRB1*11:04 YQTQTNSPRRARSVAS YQTQTNSRRRARSVAS 1929 486
HLA-DQA1*06:01/DQB1*03:01 QTNSPRRARSVASQS QTNSRRRARSVASQS 358 1412
HLA-DRB1*11:04 CASYQTQTNSPRRAR CASYQTQTNSRRRAR 1381 351
HLA-DQA1*06:01/DQB1*03:01 TQTNSPRRARSVASQS TQTNSRRRARSVASQS 375 1467
HLA-DQA1*05:01/DQB1*03:01 QTNSPRRARSVASQSI QTNSRRRARSVASQSI 125 488
HLA-DRB1*11:04 CASYQTQTNSPRRARSVASQ CASYQTQTNSRRRARSVASQ 1080 278
HLA-DPA1*04:01/DPB1*14:01 TQTNSPRRARSVASQ TQTNSRRRARSVASQ 1379 356
HLA-DRB1*11:04 ASYQTQTNSPRRARSVASQS ASYQTQTNSRRRARSVASQS 1019 276
HLA-DRB1*11:02 QTQTNSPRRARSVAS QTQTNSRRRARSVAS 901 247
HLA-DRB1*13:01 QTQTNSPRRARSVAS QTQTNSRRRARSVAS 901 247
HLA-DRB1*11:04 YQTQTNSPRRARSVASQ YQTQTNSRRRARSVASQ 1384 380
HLA-DRB1*11:01 SYQTQTNSPRRARSV SYQTQTNSRRRARSV 1303 360
HLA-DRB1*11:04 SYQTQTNSPRRARSVASQSI SYQTQTNSRRRARSVASQSI 979 271
HLA-DQA1*05:01/DQB1*03:01 CASYQTQTNSPRRARSVASQ CASYQTQTNSRRRARSVASQ 423 1518
HLA-DRB1*11:04 TQTNSPRRARSVASQ TQTNSRRRARSVASQ 1337 374
HLA-DQA1*02:01/DQB1*03:03 ASYQTQTNSPRRARSVASQS ASYQTQTNSRRRARSVASQS 447 1589
HLA-DRB1*11:02 QTNSPRRARSVASQS QTNSRRRARSVASQS 1639 464
HLA-DRB1*13:01 QTNSPRRARSVASQS QTNSRRRARSVASQS 1639 464
HLA-DRB1*11:02 TQTNSPRRARSVASQ TQTNSRRRARSVASQ 1142 333
HLA-DRB1*13:01 TQTNSPRRARSVASQ TQTNSRRRARSVASQ 1142 333
HLA-DQA1*02:01/DQB1*03:03 TQTNSPRRARSVASQS TQTNSRRRARSVASQS 465 1587
HLA-DQA1*05:01/DQB1*03:01 TQTNSPRRARSVASQSI TQTNSRRRARSVASQSI 174 586
HLA-DRB1*11:04 YQTQTNSPRRARSVASQSII YQTQTNSRRRARSVASQSII 974 290
HLA-DRB1*11:01 SYQTQTNSPRRARSVASQSI SYQTQTNSRRRARSVASQSI 1338 399
HLA-DQA1*05:01/DQB1*03:01 ASYQTQTNSPRRARSVASQS ASYQTQTNSRRRARSVASQS 327 1093
HLA-DRB1*11:02 SYQTQTNSPRRARSVAS SYQTQTNSRRRARSVAS 1047 315
HLA-DRB1*13:01 SYQTQTNSPRRARSVAS SYQTQTNSRRRARSVAS 1047 315
HLA-DRB1*11:02 YQTQTNSPRRARSVASQ YQTQTNSRRRARSVASQ 1206 367
HLA-DRB1*13:01 YQTQTNSPRRARSVASQ YQTQTNSRRRARSVASQ 1206 367
HLA-DPA1*04:01/DPB1*14:01 CASYQTQTNSPRRARSVASQ CASYQTQTNSRRRARSVASQ 954 291
HLA-DRB1*11:02 YQTQTNSPRRARSVAS YQTQTNSRRRARSVAS 1567 479
HLA-DRB1*13:01 YQTQTNSPRRARSVAS YQTQTNSRRRARSVAS 1567 479
HLA-DRB1*11:01 CASYQTQTNSPRRARSVASQ CASYQTQTNSRRRARSVASQ 1371 421
HLA-DRB1*11:01 ASYQTQTNSPRRARSVASQS ASYQTQTNSRRRARSVASQS 1320 407
HLA-DPA1*04:01/DPB1*14:01 ASYQTQTNSPRRARSVASQ ASYQTQTNSRRRARSVASQ 1601 496
HLA-DQA1*05:01/DQB1*03:01 QTQTNSPRRARSVASQSI QTQTNSRRRARSVASQSI 375 1203
HLA-DPA1*04:01/DPB1*14:01 QTQTNSPRRARSVASQ QTQTNSRRRARSVASQ 1385 432
HLA-DPA1*04:01/DPB1*14:01 ICASYQTQTNSPRRARSVAS ICASYQTQTNSRRRARSVAS 1468 458
HLA-DRB1*11:02 YQTQTNSPRRARSVA YQTQTNSRRRARSVA 570 178
HLA-DRB1*13:01 YQTQTNSPRRARSVA YQTQTNSRRRARSVA 570 178
HLA-DRB1*11:02 ASYQTQTNSPRRARSVA ASYQTQTNSRRRARSVA 982 311
HLA-DRB1*13:01 ASYQTQTNSPRRARSVA ASYQTQTNSRRRARSVA 982 311
HLA-DQA1*05:01/DQB1*03:01 TNSPRRARSVASQSII TNSRRRARSVASQSII 129 405
HLA-DRB1*08:04 CASYQTQTNSPRRARSVASQ CASYQTQTNSRRRARSVASQ 1459 465
HLA-DRB1*11:02 SYQTQTNSPRRARSV SYQTQTNSRRRARSV 513 165
HLA-DRB1*13:01 SYQTQTNSPRRARSV SYQTQTNSRRRARSV 513 165
HLA-DRB1*11:01 ICASYQTQTNSPRRARSVAS ICASYQTQTNSRRRARSVAS 1365 443
HLA-DRB1*11:02 SYQTQTNSPRRARSVA SYQTQTNSRRRARSVA 1334 437
HLA-DRB1*13:01 SYQTQTNSPRRARSVA SYQTQTNSRRRARSVA 1334 437
HLA-DRB1*11:02 CASYQTQTNSPRRARSV CASYQTQTNSRRRARSV 1090 358
HLA-DRB1*13:01 CASYQTQTNSPRRARSV CASYQTQTNSRRRARSV 1090 358
HLA-DRB1*08:04 ASYQTQTNSPRRARSVASQS ASYQTQTNSRRRARSVASQS 1290 424
HLA-DRB1*11:02 ICASYQTQTNSPRRA ICASYQTQTNSRRRA 1249 411
HLA-DRB1*13:01 ICASYQTQTNSPRRA ICASYQTQTNSRRRA 1249 411
HLA-DQA1*05:01/DQB1*03:01 YQTQTNSPRRARSVASQSI YQTQTNSRRRARSVASQSI 270 815
HLA-DRB1*11:02 ASYQTQTNSPRRARSVASQS ASYQTQTNSRRRARSVASQS 745 247
HLA-DRB1*13:01 ASYQTQTNSPRRARSVASQS ASYQTQTNSRRRARSVASQS 745 247
HLA-DRB1*11:01 ASYQTQTNSPRRARS ASYQTQTNSRRRARS 1184 394
HLA-DRB1*11:01 YQTQTNSPRRARSVASQSII YQTQTNSRRRARSVASQSII 1315 438
HLA-DRB1*08:04 SYQTQTNSPRRARSVASQSI SYQTQTNSRRRARSVASQSI 1063 356
HLA-DRB1*11:02 ASYQTQTNSPRRARS ASYQTQTNSRRRARS 600 201
HLA-DRB1*13:01 ASYQTQTNSPRRARS ASYQTQTNSRRRARS 600 201
HLA-DPA1*01:03/DPB1*03:01 QTNSPRRARSVASQS QTNSRRRARSVASQS 483 162
HLA-DPA1*04:01/DPB1*14:01 YQTQTNSPRRARSVASQ YQTQTNSRRRARSVASQ 1256 423
HLA-DRB1*11:04 QTQTNSPRRARSVASQSIIA QTQTNSRRRARSVASQSIIA 1065 359
HLA-DRB1*11:02 ICASYQTQTNSPRRARS ICASYQTQTNSRRRARS 1408 475
HLA-DRB1*13:01 ICASYQTQTNSPRRARS ICASYQTQTNSRRRARS 1408 475
HLA-DRB1*11:02 CASYQTQTNSPRRARSVASQ CASYQTQTNSRRRARSVASQ 738 250
HLA-DRB1*13:01 CASYQTQTNSPRRARSVASQ CASYQTQTNSRRRARSVASQ 738 250
HLA-DRB1*11:02 ASYQTQTNSPRRARSV ASYQTQTNSRRRARSV 1265 432
HLA-DRB1*13:01 ASYQTQTNSPRRARSV ASYQTQTNSRRRARSV 1265 432
HLA-DPA1*01:03/DPB1*03:01 SYQTQTNSPRRARSVASQS SYQTQTNSRRRARSVASQS 816 280
HLA-DRB1*11:02 ICASYQTQTNSPRRARSVAS ICASYQTQTNSRRRARSVAS 749 259
HLA-DRB1*13:01 ICASYQTQTNSPRRARSVAS ICASYQTQTNSRRRARSVAS 749 259
HLA-DQA1*05:01/DQB1*03:01 QTNSPRRARSVASQSII QTNSRRRARSVASQSII 173 500
HLA-DRB1*11:01 GICASYQTQTNSPRRARSVA GICASYQTQTNSRRRARSVA 1397 484
HLA-DPA1*01:03/DPB1*03:01 QTQTNSPRRARSVASQS QTQTNSRRRARSVASQS 614 214
HLA-DRB1*11:02 SYQTQTNSPRRARSVASQSI SYQTQTNSRRRARSVASQSI 725 254
HLA-DRB1*13:01 SYQTQTNSPRRARSVASQSI SYQTQTNSRRRARSVASQSI 725 254
HLA-DRB1*11:02 GICASYQTQTNSPRRARSVA GICASYQTQTNSRRRARSVA 802 283
HLA-DRB1*13:01 GICASYQTQTNSPRRARSVA GICASYQTQTNSRRRARSVA 802 283
HLA-DRB1*11:02 CASYQTQTNSPRRAR CASYQTQTNSRRRAR 699 247
HLA-DRB1*13:01 CASYQTQTNSPRRAR CASYQTQTNSRRRAR 699 247
HLA-DRB1*11:02 ASYQTQTNSPRRARSVASQ ASYQTQTNSRRRARSVASQ 1318 466
HLA-DRB1*13:01 ASYQTQTNSPRRARSVASQ ASYQTQTNSRRRARSVASQ 1318 466
HLA-DRB1*11:02 GAGICASYQTQTNSPRRARS GAGICASYQTQTNSRRRARS 1149 407
HLA-DRB1*13:01 GAGICASYQTQTNSPRRARS GAGICASYQTQTNSRRRARS 1149 407
HLA-DQA1*05:01/DQB1*03:01 NSPRRARSVASQSII NSRRRARSVASQSII 135 380
HLA-DRB1*11:02 AGICASYQTQTNSPRRARSV AGICASYQTQTNSRRRARSV 880 313
HLA-DRB1*13:01 AGICASYQTQTNSPRRARSV AGICASYQTQTNSRRRARSV 880 313
HLA-DRB1*11:01 CASYQTQTNSPRRAR CASYQTQTNSRRRAR 1341 484
HLA-DQA1*05:01/DQB1*03:01 TQTNSPRRARSVASQSII TQTNSRRRARSVASQSII 369 1022
HLA-DRB1*08:04 YQTQTNSPRRARSVASQSII YQTQTNSRRRARSVASQSII 957 346
HLA-DRB1*11:02 CASYQTQTNSPRRARSVAS CASYQTQTNSRRRARSVAS 1332 487
HLA-DRB1*13:01 CASYQTQTNSPRRARSVAS CASYQTQTNSRRRARSVAS 1332 487
HLA-DRB1*11:01 QTQTNSPRRARSVASQSIIA QTQTNSRRRARSVASQSIIA 1351 495
HLA-DPA1*01:03/DPB1*03:01 TNSPRRARSVASQSI TNSRRRARSVASQSI 232 86
HLA-DQA1*05:01/DQB1*06:01 TQTNSPRRARSVASQ TQTNSRRRARSVASQ 391 1053
HLA-DPA1*01:03/DPB1*03:01 YQTQTNSPRRARSVASQSI YQTQTNSRRRARSVASQSI 346 129
HLA-DQA1*05:01/DQB1*06:01 QTQTNSPRRARSVASQ QTQTNSRRRARSVASQ 470 1260
HLA-DPA1*02:02/DPB1*03:01 TNSPRRARSVASQSI TNSRRRARSVASQSI 1193 446
HLA-DPA1*01:03/DPB1*03:01 ASYQTQTNSPRRARSVASQS ASYQTQTNSRRRARSVASQS 347 130
HLA-DQA1*05:01/DQB1*06:01 QTNSPRRARSVASQS QTNSRRRARSVASQS 344 917
HLA-DRB1*11:02 YQTQTNSPRRARSVASQSII YQTQTNSRRRARSVASQSII 749 284
HLA-DRB1*13:01 YQTQTNSPRRARSVASQSII YQTQTNSRRRARSVASQSII 749 284
HLA-DQA1*05:01/DQB1*03:01 QTQTNSPRRARSVASQSII QTQTNSRRRARSVASQSII 266 700
HLA-DRB1*11:02 TNSPRRARSVASQSI TNSRRRARSVASQSI 1036 395
HLA-DRB1*13:01 TNSPRRARSVASQSI TNSRRRARSVASQSI 1036 395
HLA-DQA1*05:01/DQB1*06:01 QTQTNSPRRARSVAS QTQTNSRRRARSVAS 488 1274
HLA-DQA1*05:01/DQB1*03:01 SYQTQTNSPRRARSVASQSI SYQTQTNSRRRARSVASQSI 243 633
HLA-DQA1*05:01/DQB1*06:01 TQTNSPRRARSVASQS TQTNSRRRARSVASQS 417 1080
HLA-DPA1*01:03/DPB1*03:01 TQTNSPRRARSVASQS TQTNSRRRARSVASQS 535 207
HLA-DRB1*11:02 IGAGICASYQTQTNSPRRAR IGAGICASYQTQTNSRRRAR 1273 494
HLA-DRB1*13:01 IGAGICASYQTQTNSPRRAR IGAGICASYQTQTNSRRRAR 1273 494
HLA-DQA1*06:01/DQB1*03:01 QTNSPRRARSVASQSI QTNSRRRARSVASQSI 253 650
HLA-DPA1*01:03/DPB1*03:01 TQTNSPRRARSVASQSI TQTNSRRRARSVASQSI 272 106
HLA-DQA1*06:01/DQB1*03:01 TNSPRRARSVASQSI TNSRRRARSVASQSI 232 592
HLA-DQA1*05:01/DQB1*06:01 QTQTNSPRRARSVASQS QTQTNSRRRARSVASQS 462 1175
HLA-DPA1*02:02/DPB1*14:01 SYQTQTNSPRRARSVASQSI SYQTQTNSRRRARSVASQSI 737 290
HLA-DRB1*11:02 QTQTNSPRRARSVASQSIIA QTQTNSRRRARSVASQSIIA 811 321
HLA-DRB1*13:01 QTQTNSPRRARSVASQSIIA QTQTNSRRRARSVASQSIIA 811 321
HLA-DPA1*02:02/DPB1*03:01 SYQTQTNSPRRARSVASQSI SYQTQTNSRRRARSVASQSI 912 363
HLA-DQA1*01:03/DQB1*06:01 SYQTQTNSPRRARSV SYQTQTNSRRRARSV 426 1070
HLA-DPA1*02:02/DPB1*14:01 TNSPRRARSVASQSI TNSRRRARSVASQSI 802 321
HLA-DPA1*01:03/DPB1*06:01 QTNSPRRARSVASQS QTNSRRRARSVASQS 1044 418
HLA-DRB1*08:04 QTQTNSPRRARSVASQSIIA QTQTNSRRRARSVASQSIIA 899 363
HLA-DPA1*01:03/DPB1*06:01 ASYQTQTNSPRRARSVASQS ASYQTQTNSRRRARSVASQS 777 315
HLA-DPA1*01:03/DPB1*03:01 SYQTQTNSPRRARSVASQSI SYQTQTNSRRRARSVASQSI 143 58
HLA-DRB1*08:04 TNSPRRARSVASQSI TNSRRRARSVASQSI 1225 497
HLA-DPA1*02:01/DPB1*14:01 SYQTQTNSPRRARSVASQSI SYQTQTNSRRRARSVASQSI 956 392
HLA-DPA1*02:02/DPB1*14:01 TQTNSPRRARSVASQSI TQTNSRRRARSVASQSI 953 396
HLA-DQA1*01:03/DQB1*06:01 YQTQTNSPRRARSVA YQTQTNSRRRARSVA 443 1064
HLA-DQA1*05:01/DQB1*03:01 TNSPRRARSVASQSIIA TNSRRRARSVASQSIIA 169 403
HLA-DPA1*02:02/DPB1*14:01 QTNSPRRARSVASQSI QTNSRRRARSVASQSI 933 393
HLA-DPA1*01:03/DPB1*03:01 QTQTNSPRRARSVASQSII QTQTNSRRRARSVASQSII 206 87
HLA-DPA1*01:03/DPB1*06:01 QTQTNSPRRARSVASQS QTQTNSRRRARSVASQS 1150 486
HLA-DQA1*05:01/DQB1*03:01 QTNSPRRARSVASQSIIA QTNSRRRARSVASQSIIA 355 840
HLA-DQA1*05:01/DQB1*06:01 ASYQTQTNSPRRARSVASQS ASYQTQTNSRRRARSVASQS 470 1110
HLA-DQA1*05:01/DQB1*03:01 YQTQTNSPRRARSVASQSII YQTQTNSRRRARSVASQSII 235 554
HLA-DPA1*01:03/DPB1*06:01 TNSPRRARSVASQSI TNSRRRARSVASQSI 498 212
HLA-DPA1*01:03/DPB1*03:01 NSPRRARSVASQSII NSRRRARSVASQSII 142 61
HLA-DPA1*01:03/DPB1*03:01 QTNSPRRARSVASQSI QTNSRRRARSVASQSI 258 111
HLA-DPA1*01:03/DPB1*06:01 SYQTQTNSPRRARSVASQSI SYQTQTNSRRRARSVASQSI 336 145
HLA-DQA1*06:01/DQB1*03:01 TQTNSPRRARSVASQSI TQTNSRRRARSVASQSI 357 827
HLA-DQA1*05:01/DQB1*03:01 TQTNSPRRARSVASQSIIA TQTNSRRRARSVASQSIIA 259 595
HLA-DPA1*01:03/DPB1*06:01 YQTQTNSPRRARSVASQSI YQTQTNSRRRARSVASQSI 726 317
HLA-DPA1*01:03/DPB1*06:01 TQTNSPRRARSVASQS TQTNSRRRARSVASQS 1131 497
HLA-DRB1*10:01 QTNSPRRARSVASQS QTNSRRRARSVASQS 879 387
HLA-DQA1*06:01/DQB1*03:01 TNSPRRARSVASQSII TNSRRRARSVASQSII 239 542
HLA-DPA1*04:01/DPB1*14:01 QTNSPRRARSVASQS QTNSRRRARSVASQS 400 178
HLA-DPA1*01:03/DPB1*03:01 QTNSPRRARSVASQSII QTNSRRRARSVASQSII 166 74
HLA-DRB1*11:04 TQTNSPRRARSVASQSIIAY TQTNSRRRARSVASQSIIAY 925 413
HLA-DRB1*10:01 TQTNSPRRARSVASQSI TQTNSRRRARSVASQSI 525 235
HLA-DPA1*02:02/DPB1*03:01 TNSPRRARSVASQSII TNSRRRARSVASQSII 825 370
HLA-DPA1*02:01/DPB1*14:01 QTNSPRRARSVASQSII QTNSRRRARSVASQSII 875 393
HLA-DPA1*01:03/DPB1*03:01 TQTNSPRRARSVASQSIIA TQTNSRRRARSVASQSIIA 162 73
HLA-DPA1*01:03/DPB1*03:01 SPRRARSVASQSIIA SRRRARSVASQSIIA 117 53
HLA-DPA1*01:03/DPB1*17:01 SYQTQTNSPRRARSVASQSI SYQTQTNSRRRARSVASQSI 929 421
HLA-DPA1*02:02/DPB1*03:01 YQTQTNSPRRARSVASQSII YQTQTNSRRRARSVASQSII 578 262
HLA-DPA1*01:03/DPB1*06:01 TQTNSPRRARSVASQSI TQTNSRRRARSVASQSI 531 241
HLA-DQA1*05:01/DQB1*03:01 NSPRRARSVASQSIIA NSRRRARSVASQSIIA 151 332
HLA-DQA1*06:01/DQB1*06:01 SYQTQTNSPRRARSVASQSI SYQTQTNSRRRARSVASQSI 414 907
HLA-DQA1*01:03/DQB1*06:01 SYQTQTNSPRRARSVA SYQTQTNSRRRARSVA 468 1021
HLA-DQA1*06:01/DQB1*03:01 YQTQTNSPRRARSVASQSI YQTQTNSRRRARSVASQSI 469 1023
HLA-DPA1*02:02/DPB1*03:01 QTNSPRRARSVASQSII QTNSRRRARSVASQSII 838 385
HLA-DPA1*01:03/DPB1*03:01 QTNSPRRARSVASQSIIAY QTNSRRRARSVASQSIIAY 152 70
HLA-DQA1*05:01/DQB1*06:01 TNSPRRARSVASQSI TNSRRRARSVASQSI 243 525
HLA-DQA1*06:01/DQB1*03:01 SYQTQTNSPRRARSVASQSI SYQTQTNSRRRARSVASQSI 379 818
HLA-DRB1*11:02 NSPRRARSVASQSII NSRRRARSVASQSII 732 340
HLA-DRB1*13:01 NSPRRARSVASQSII NSRRRARSVASQSII 732 340
HLA-DPA1*01:03/DPB1*03:01 TNSPRRARSVASQSIIAYT TNSRRRARSVASQSIIAYT 148 69
HLA-DQA1*01:03/DQB1*06:01 YQTQTNSPRRARSVASQ YQTQTNSRRRARSVASQ 239 512
HLA-DRB1*08:02 SYQTQTNSPRRARSVASQSI SYQTQTNSRRRARSVASQSI 936 437
HLA-DRB1*10:01 QTNSPRRARSVASQSI QTNSRRRARSVASQSI 696 325
HLA-DRB1*10:01 TNSPRRARSVASQSI TNSRRRARSVASQSI 349 163
HLA-DPA1*02:02/DPB1*14:01 YQTQTNSPRRARSVASQSII YQTQTNSRRRARSVASQSII 389 182
HLA-DPA1*04:01/DPB1*14:01 SYQTQTNSPRRARSVASQS SYQTQTNSRRRARSVASQS 517 242
HLA-DPA1*02:02/DPB1*03:01 NSPRRARSVASQSII NSRRRARSVASQSII 722 338
HLA-DQA1*05:01/DQB1*03:01 QTQTNSPRRARSVASQSIIA QTQTNSRRRARSVASQSIIA 221 471
HLA-DQA1*06:01/DQB1*06:01 QTNSPRRARSVASQSI QTNSRRRARSVASQSI 383 816
HLA-DPA1*01:03/DPB1*06:01 NSPRRARSVASQSII NSRRRARSVASQSII 313 147
HLA-DRB1*10:01 QTNSPRRARSVASQSII QTNSRRRARSVASQSII 347 163
HLA-DPA1*01:03/DPB1*03:01 NSPRRARSVASQSIIAYTM NSRRRARSVASQSIIAYTM 153 72
HLA-DQA1*01:03/DQB1*06:01 CASYQTQTNSPRRARSVASQ CASYQTQTNSRRRARSVASQ 199 422
HLA-DPA1*01:03/DPB1*03:01 PRRARSVASQSIIAY RRRARSVASQSIIAY 127 60
HLA-DQA1*05:01/DQB1*06:01 QTNSPRRARSVASQSI QTNSRRRARSVASQSI 302 639
HLA-DPA1*01:03/DPB1*03:01 TNSPRRARSVASQSII TNSRRRARSVASQSII 167 79
HLA-DPA1*02:01/DPB1*14:01 YQTQTNSPRRARSVASQSII YQTQTNSRRRARSVASQSII 507 240
HLA-DPA1*02:01/DPB1*14:01 TNSPRRARSVASQSII TNSRRRARSVASQSII 866 410
HLA-DPA1*02:01/DPB1*14:01 NSPRRARSVASQSII NSRRRARSVASQSII 719 341
HLA-DPA1*04:01/DPB1*14:01 ASYQTQTNSPRRARSVASQS ASYQTQTNSRRRARSVASQS 293 139
HLA-DPA1*01:03/DPB1*06:01 QTNSPRRARSVASQSI QTNSRRRARSVASQSI 533 253
HLA-DPA1*01:03/DPB1*03:01 SPRRARSVASQSIIAYTMS SRRRARSVASQSIIAYTMS 158 75
HLA-DQA1*05:01/DQB1*06:01 YQTQTNSPRRARSVASQSI YQTQTNSRRRARSVASQSI 441 929
HLA-DQA1*06:01/DQB1*06:01 TNSPRRARSVASQSI TNSRRRARSVASQSI 340 716
HLA-DRB1*11:02 TQTNSPRRARSVASQSIIAY TQTNSRRRARSVASQSIIAY 577 274
HLA-DRB1*13:01 TQTNSPRRARSVASQSIIAY TQTNSRRRARSVASQSIIAY 577 274
HLA-DPA1*01:03/DPB1*03:01 YQTQTNSPRRARSVASQSII YQTQTNSRRRARSVASQSII 84 40
HLA-DRB1*08:04 NSPRRARSVASQSII NSRRRARSVASQSII 1001 477
HLA-DPA1*01:03/DPB1*03:01 TNSPRRARSVASQSIIA TNSRRRARSVASQSIIA 132 63
HLA-DQA1*05:01/DQB1*06:01 TQTNSPRRARSVASQSI TQTNSRRRARSVASQSI 333 697
HLA-DQA1*01:03/DQB1*06:01 ASYQTQTNSPRRARSVASQS ASYQTQTNSRRRARSVASQS 165 345
HLA-DQA1*01:03/DQB1*06:01 SYQTQTNSPRRARSVASQS SYQTQTNSRRRARSVASQS 262 546
HLA-DPA1*01:03/DPB1*06:01 SPRRARSVASQSIIA SRRRARSVASQSIIA 253 122
HLA-DPA1*01:03/DPB1*06:01 QTQTNSPRRARSVASQSII QTQTNSRRRARSVASQSII 425 205
HLA-DPA1*04:01/DPB1*14:01 QTQTNSPRRARSVASQS QTQTNSRRRARSVASQS 416 201
HLA-DRB1*08:04 TQTNSPRRARSVASQSIIAY TQTNSRRRARSVASQSIIAY 689 333
HLA-DRB1*10:01 QTQTNSPRRARSVASQSII QTQTNSRRRARSVASQSII 525 255
HLA-DQA1*01:03/DQB1*06:01 YQTQTNSPRRARSVAS YQTQTNSRRRARSVAS 260 535
HLA-DPA1*04:01/DPB1*14:01 TNSPRRARSVASQSI TNSRRRARSVASQSI 216 105
HLA-DQA1*05:01/DQB1*06:01 SYQTQTNSPRRARSVASQSI SYQTQTNSRRRARSVASQSI 352 722
HLA-DPA1*01:03/DPB1*03:01 NSPRRARSVASQSIIAY NSRRRARSVASQSIIAY 127 62
HLA-DRB1*11:04 QTNSPRRARSVASQSIIAYT QTNSRRRARSVASQSIIAYT 961 470
HLA-DPA1*02:01/DPB1*14:01 TQTNSPRRARSVASQSIIA TQTNSRRRARSVASQSIIA 824 403
HLA-DQA1*06:01/DQB1*06:01 TQTNSPRRARSVASQSI TQTNSRRRARSVASQSI 427 873
HLA-DRB1*10:01 TNSPRRARSVASQSII TNSRRRARSVASQSII 470 230
HLA-DQA1*01:03/DQB1*06:01 SYQTQTNSPRRARSVASQ SYQTQTNSRRRARSVASQ 469 956
HLA-DPA1*02:02/DPB1*14:01 QTNSPRRARSVASQSII QTNSRRRARSVASQSII 525 258
HLA-DPA1*01:03/DPB1*03:01 SPRRARSVASQSIIAYT SRRRARSVASQSIIAYT 126 62
HLA-DQA1*01:02/DQB1*06:01 YQTQTNSPRRARSVAS YQTQTNSRRRARSVAS 404 821
HLA-DRB1*08:02 YQTQTNSPRRARSVASQSII YQTQTNSRRRARSVASQSII 810 400
HLA-DRB1*10:01 YQTQTNSPRRARSVASQSI YQTQTNSRRRARSVASQSI 740 366
HLA-DQA1*06:01/DQB1*03:01 NSPRRARSVASQSII NSRRRARSVASQSII 254 513
HLA-DRB1*07:01 QTNSPRRARSVASQSI QTNSRRRARSVASQSI 345 171
HLA-DPA1*02:02/DPB1*14:01 NSPRRARSVASQSII NSRRRARSVASQSII 468 232
HLA-DPA1*04:01/DPB1*14:01 YQTQTNSPRRARSVASQSI YQTQTNSRRRARSVASQSI 286 142
HLA-DPA1*02:01/DPB1*14:01 TNSPRRARSVASQSIIA TNSRRRARSVASQSIIA 594 295
HLA-DPA1*02:02/DPB1*03:01 NSPRRARSVASQSIIA NSRRRARSVASQSIIA 598 297
HLA-DQA1*01:03/DQB1*06:01 ASYQTQTNSPRRARSVASQ ASYQTQTNSRRRARSVASQ 308 620
HLA-DQA1*06:01/DQB1*03:01 QTNSPRRARSVASQSII QTNSRRRARSVASQSII 341 686
HLA-DQA1*01:03/DQB1*06:01 QTQTNSPRRARSVASQ QTQTNSRRRARSVASQ 255 512
HLA-DPA1*02:02/DPB1*14:01 QTQTNSPRRARSVASQSII QTQTNSRRRARSVASQSII 877 437
HLA-DPA1*02:02/DPB1*03:01 TNSPRRARSVASQSIIA TNSRRRARSVASQSIIA 594 296
HLA-DPA1*01:03/DPB1*03:01 QTQTNSPRRARSVASQSIIA QTQTNSRRRARSVASQSIIA 66 33
HLA-DPA1*01:03/DPB1*03:01 NSPRRARSVASQSIIA NSRRRARSVASQSIIA 142 71
HLA-DPA1*01:03/DPB1*06:01 YQTQTNSPRRARSVASQSII YQTQTNSRRRARSVASQSII 196 98
HLA-DRB1*07:01 TQTNSPRRARSVASQSI TQTNSRRRARSVASQSI 280 140
HLA-DQA1*01:03/DQB1*06:01 QTQTNSPRRARSVASQS QTQTNSRRRARSVASQS 238 476

D950N

Reference  NQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISS
           ||||||||||||||||||||||||| |||||||||||||||||||||||||
Mutated    NQFNSAIGKIQDSLSSTASALGKLQNVVNQNAQALNTLVKQLSSNFGAISS

Export table to csv 
Allele Reference peptide Mutated peptide Reference affinity (IC50, nM) Mutated affinity (IC50, nM)
HLA-DRB1*01:01 ASALGKLQDVVNQNA ASALGKLQNVVNQNA 862 124
HLA-DRB1*01:01 TASALGKLQDVVNQN TASALGKLQNVVNQN 1276 198
HLA-DRB1*01:01 SALGKLQDVVNQNAQ SALGKLQNVVNQNAQ 647 116
HLA-DRB1*10:01 TASALGKLQDVVNQN TASALGKLQNVVNQN 727 144
HLA-DRB1*01:01 TASALGKLQDVVNQNAQ TASALGKLQNVVNQNAQ 1652 346
HLA-DRB1*10:01 STASALGKLQDVVNQNA STASALGKLQNVVNQNA 806 169
HLA-DRB1*10:01 TASALGKLQDVVNQNAQ TASALGKLQNVVNQNAQ 672 141
HLA-DRB1*10:01 STASALGKLQDVVNQ STASALGKLQNVVNQ 743 159
HLA-DRB1*10:01 SSTASALGKLQDVVNQN SSTASALGKLQNVVNQN 1223 265
HLA-DRB1*04:04 TASALGKLQDVVNQNAQ TASALGKLQNVVNQNAQ 483 105
HLA-DRB1*01:01 ASALGKLQDVVNQNAQA ASALGKLQNVVNQNAQA 1178 257
HLA-DRB1*01:01 STASALGKLQDVVNQ STASALGKLQNVVNQ 1011 224
HLA-DRB1*01:01 ALGKLQDVVNQNAQA ALGKLQNVVNQNAQA 459 103
HLA-DRB1*04:04 STASALGKLQDVVNQNAQA STASALGKLQNVVNQNAQA 449 101
HLA-DRB1*15:01 ALGKLQDVVNQNAQA ALGKLQNVVNQNAQA 1111 250
HLA-DRB1*10:01 STASALGKLQDVVNQN STASALGKLQNVVNQN 1471 332
HLA-DRB1*15:01 SALGKLQDVVNQNAQ SALGKLQNVVNQNAQ 1820 411
HLA-DRB1*01:01 ASALGKLQDVVNQNAQ ASALGKLQNVVNQNAQ 1675 380
HLA-DRB1*10:01 ASALGKLQDVVNQNA ASALGKLQNVVNQNA 418 95
HLA-DRB1*04:04 SSTASALGKLQDVVNQNAQ SSTASALGKLQNVVNQNAQ 783 178
HLA-DRB1*04:04 ASALGKLQDVVNQNAQ ASALGKLQNVVNQNAQ 421 98
HLA-DRB1*01:01 STASALGKLQDVVNQNA STASALGKLQNVVNQNA 1882 440
HLA-DRB1*04:04 ASALGKLQDVVNQNAQA ASALGKLQNVVNQNAQA 280 66
HLA-DRB1*10:01 TASALGKLQDVVNQNA TASALGKLQNVVNQNA 876 210
HLA-DRB1*10:01 ASALGKLQDVVNQNAQA ASALGKLQNVVNQNAQA 519 125
HLA-DRB1*01:01 SALGKLQDVVNQNAQA SALGKLQNVVNQNAQA 1215 294
HLA-DRB1*04:04 ASALGKLQDVVNQNAQAL ASALGKLQNVVNQNAQAL 623 151
HLA-DRB1*10:01 SSTASALGKLQDVVNQNAQ SSTASALGKLQNVVNQNAQ 820 199
HLA-DRB1*04:04 SALGKLQDVVNQNAQALN SALGKLQNVVNQNAQALN 617 150
HLA-DRB1*08:02 ASALGKLQDVVNQNAQA ASALGKLQNVVNQNAQA 1899 463
HLA-DRB1*04:04 ALGKLQDVVNQNAQALNT ALGKLQNVVNQNAQALNT 648 158
HLA-DRB1*04:04 TASALGKLQDVVNQNAQA TASALGKLQNVVNQNAQA 902 220
HLA-DRB1*04:04 STASALGKLQDVVNQNAQ STASALGKLQNVVNQNAQ 1554 382
HLA-DRB1*10:01 ASALGKLQDVVNQNAQ ASALGKLQNVVNQNAQ 683 168
HLA-DRB1*04:04 TASALGKLQDVVNQNAQAL TASALGKLQNVVNQNAQAL 309 77
HLA-DRB1*04:04 LGKLQDVVNQNAQALNTL LGKLQNVVNQNAQALNTL 706 176
HLA-DRB1*10:01 SALGKLQDVVNQNAQ SALGKLQNVVNQNAQ 371 93
HLA-DRB1*01:01 SSTASALGKLQDVVNQNAQA SSTASALGKLQNVVNQNAQA 793 199
HLA-DRB1*04:04 SALGKLQDVVNQNAQ SALGKLQNVVNQNAQ 207 52
HLA-DRB1*08:02 SALGKLQDVVNQNAQ SALGKLQNVVNQNAQ 1578 398
HLA-DRB1*04:04 ASALGKLQDVVNQNA ASALGKLQNVVNQNA 463 117
HLA-DRB1*10:01 SSTASALGKLQDVVNQ SSTASALGKLQNVVNQ 1515 383
HLA-DRB1*15:01 SALGKLQDVVNQNAQAL SALGKLQNVVNQNAQAL 1450 368
HLA-DRB1*10:01 STASALGKLQDVVNQNAQA STASALGKLQNVVNQNAQA 645 165
HLA-DRB1*01:01 STASALGKLQDVVNQNAQA STASALGKLQNVVNQNAQA 1523 391
HLA-DRB1*04:04 SALGKLQDVVNQNAQA SALGKLQNVVNQNAQA 253 65
HLA-DRB1*04:04 SSTASALGKLQDVVNQNAQA SSTASALGKLQNVVNQNAQA 323 83
HLA-DRB1*04:04 ASALGKLQDVVNQNAQALN ASALGKLQNVVNQNAQALN 291 75
HLA-DRB1*10:01 LSSTASALGKLQDVVNQNA LSSTASALGKLQNVVNQNA 904 233
HLA-DRB1*08:04 SALGKLQDVVNQNAQ SALGKLQNVVNQNAQ 1607 415
HLA-DRB1*04:04 LSSTASALGKLQDVVNQNAQ LSSTASALGKLQNVVNQNAQ 558 145
HLA-DRB1*04:04 STASALGKLQDVVNQNA STASALGKLQNVVNQNA 1130 294
HLA-DRB1*04:04 ALGKLQDVVNQNAQALN ALGKLQNVVNQNAQALN 198 52
HLA-DRB1*08:02 ALGKLQDVVNQNAQA ALGKLQNVVNQNAQA 1062 279
HLA-DRB1*04:01 SALGKLQDVVNQNAQ SALGKLQNVVNQNAQ 456 120
HLA-DRB1*04:04 LGKLQDVVNQNAQALNT LGKLQNVVNQNAQALNT 216 57
HLA-DRB1*04:04 SALGKLQDVVNQNAQAL SALGKLQNVVNQNAQAL 197 52
HLA-DRB1*15:01 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 678 179
HLA-DRB1*04:04 SALGKLQDVVNQNAQALNT SALGKLQNVVNQNAQALNT 290 77
HLA-DRB1*04:04 TASALGKLQDVVNQNA TASALGKLQNVVNQNA 1028 273
HLA-DRB1*04:01 ASALGKLQDVVNQNAQA ASALGKLQNVVNQNAQA 628 167
HLA-DRB1*08:02 SALGKLQDVVNQNAQA SALGKLQNVVNQNAQA 1667 445
HLA-DRB1*04:04 GKLQDVVNQNAQALNT GKLQNVVNQNAQALNT 283 76
HLA-DRB1*15:01 ALGKLQDVVNQNAQAL ALGKLQNVVNQNAQAL 1359 365
HLA-DRB1*04:01 TASALGKLQDVVNQNAQ TASALGKLQNVVNQNAQ 980 265
HLA-DRB1*08:02 SALGKLQDVVNQNAQAL SALGKLQNVVNQNAQAL 1335 361
HLA-DRB1*04:04 GKLQDVVNQNAQALNTL GKLQNVVNQNAQALNTL 314 85
HLA-DRB1*11:02 ALGKLQDVVNQNAQA ALGKLQNVVNQNAQA 1176 319
HLA-DRB1*13:01 ALGKLQDVVNQNAQA ALGKLQNVVNQNAQA 1176 319
HLA-DRB1*08:04 ALGKLQDVVNQNAQA ALGKLQNVVNQNAQA 1124 305
HLA-DRB1*04:01 STASALGKLQDVVNQNAQA STASALGKLQNVVNQNAQA 950 260
HLA-DRB1*04:04 LGKLQDVVNQNAQALN LGKLQNVVNQNAQALN 189 52
HLA-DRB1*04:04 GKLQDVVNQNAQALNTLV GKLQNVVNQNAQALNTLV 1099 303
HLA-DRB1*15:01 ALGKLQDVVNQNAQALN ALGKLQNVVNQNAQALN 1265 349
HLA-DRB1*04:04 ALGKLQDVVNQNAQAL ALGKLQNVVNQNAQAL 181 50
HLA-DRB1*04:01 ALGKLQDVVNQNAQA ALGKLQNVVNQNAQA 310 86
HLA-DRB1*04:01 ASALGKLQDVVNQNAQ ASALGKLQNVVNQNAQ 901 250
HLA-DRB1*04:01 SALGKLQDVVNQNAQA SALGKLQNVVNQNAQA 590 164
HLA-DRB1*08:04 SALGKLQDVVNQNAQAL SALGKLQNVVNQNAQAL 1675 466
HLA-DRB1*08:02 ALGKLQDVVNQNAQALN ALGKLQNVVNQNAQALN 1298 362
HLA-DRB1*01:02 ASALGKLQDVVNQNA ASALGKLQNVVNQNA 1411 394
HLA-DRB1*13:02 SALGKLQDVVNQNAQ SALGKLQNVVNQNAQ 1329 374
HLA-DRB1*04:04 ALGKLQDVVNQNAQALNTL ALGKLQNVVNQNAQALNTL 287 81
HLA-DRB1*04:04 ALGKLQDVVNQNAQA ALGKLQNVVNQNAQA 134 38
HLA-DRB1*04:01 ALGKLQDVVNQNAQAL ALGKLQNVVNQNAQAL 444 126
HLA-DRB1*11:04 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 1588 451
HLA-DRB1*04:01 ALGKLQDVVNQNAQALN ALGKLQNVVNQNAQALN 457 130
HLA-DRB1*04:04 LGKLQDVVNQNAQALNTLV LGKLQNVVNQNAQALNTLV 326 93
HLA-DRB1*08:02 LGKLQDVVNQNAQALN LGKLQNVVNQNAQALN 1218 349
HLA-DRB1*08:04 ALGKLQDVVNQNAQALN ALGKLQNVVNQNAQALN 1615 463
HLA-DRB1*04:01 SALGKLQDVVNQNAQAL SALGKLQNVVNQNAQAL 453 130
HLA-DRB1*04:04 TASALGKLQDVVNQN TASALGKLQNVVNQN 1575 452
HLA-DRB1*04:02 SALGKLQDVVNQNAQ SALGKLQNVVNQNAQ 1051 302
HLA-DRB1*08:02 ALGKLQDVVNQNAQAL ALGKLQNVVNQNAQAL 1211 348
HLA-DRB1*04:01 LGKLQDVVNQNAQALNT LGKLQNVVNQNAQALNT 488 141
HLA-DRB1*04:01 LGKLQDVVNQNAQALN LGKLQNVVNQNAQALN 452 131
HLA-DRB1*10:01 SALGKLQDVVNQNAQA SALGKLQNVVNQNAQA 547 159
HLA-DRB1*04:01 ASALGKLQDVVNQNAQAL ASALGKLQNVVNQNAQAL 1283 373
HLA-DRB1*10:01 SSTASALGKLQDVVNQNAQA SSTASALGKLQNVVNQNAQA 392 114
HLA-DRB1*04:02 STASALGKLQDVVNQNAQAL STASALGKLQNVVNQNAQAL 1562 455
HLA-DRB1*04:01 GKLQDVVNQNAQALN GKLQNVVNQNAQALN 322 94
HLA-DRB1*04:04 STASALGKLQDVVNQNAQAL STASALGKLQNVVNQNAQAL 226 66
HLA-DRB1*08:02 LGKLQDVVNQNAQALNT LGKLQNVVNQNAQALNT 1300 382
HLA-DRB1*04:01 SALGKLQDVVNQNAQALN SALGKLQNVVNQNAQALN 1252 368
HLA-DRB1*08:02 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 811 239
HLA-DRB1*04:01 SSTASALGKLQDVVNQNAQ SSTASALGKLQNVVNQNAQ 1512 450
HLA-DRB1*04:01 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 245 73
HLA-DRB1*04:04 GKLQDVVNQNAQALN GKLQNVVNQNAQALN 144 43
HLA-DRB1*08:02 GKLQDVVNQNAQALN GKLQNVVNQNAQALN 976 292
HLA-DRB1*10:01 LSSTASALGKLQDVVNQNAQ LSSTASALGKLQNVVNQNAQ 447 134
HLA-DRB1*10:01 TASALGKLQDVVNQNAQAL TASALGKLQNVVNQNAQAL 470 141
HLA-DRB1*04:01 ALGKLQDVVNQNAQALNT ALGKLQNVVNQNAQALNT 1278 384
HLA-DRB1*08:04 LGKLQDVVNQNAQALNT LGKLQNVVNQNAQALNT 1639 494
HLA-DRB1*08:02 GKLQDVVNQNAQALNT GKLQNVVNQNAQALNT 1487 449
HLA-DRB1*08:04 ALGKLQDVVNQNAQAL ALGKLQNVVNQNAQAL 1589 481
HLA-DRB1*15:01 LGKLQDVVNQNAQALN LGKLQNVVNQNAQALN 1168 354
HLA-DRB1*04:02 ALGKLQDVVNQNAQA ALGKLQNVVNQNAQA 639 194
HLA-DRB1*15:01 STASALGKLQDVVNQNAQAL STASALGKLQNVVNQNAQAL 1192 362
HLA-DRB1*01:01 SALGKLQDVVNQNAQAL SALGKLQNVVNQNAQAL 638 194
HLA-DRB1*08:02 SSTASALGKLQDVVNQNAQA SSTASALGKLQNVVNQNAQA 1516 461
HLA-DRB1*10:01 SALGKLQDVVNQNAQAL SALGKLQNVVNQNAQAL 394 120
HLA-DRB1*04:02 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 513 157
HLA-DRB1*04:02 TASALGKLQDVVNQNAQALN TASALGKLQNVVNQNAQALN 1354 415
HLA-DRB1*13:02 ALGKLQDVVNQNAQA ALGKLQNVVNQNAQA 501 154
HLA-DRB1*15:01 LGKLQDVVNQNAQALNT LGKLQNVVNQNAQALNT 1184 364
HLA-DRB1*04:02 ASALGKLQDVVNQNAQA ASALGKLQNVVNQNAQA 1486 457
HLA-DRB1*04:01 SSTASALGKLQDVVNQNAQA SSTASALGKLQNVVNQNAQA 702 217
HLA-DRB1*08:04 GKLQDVVNQNAQALN GKLQNVVNQNAQALN 1115 345
HLA-DRB1*10:01 LSSTASALGKLQDVVNQ LSSTASALGKLQNVVNQ 880 273
HLA-DRB1*04:04 TASALGKLQDVVNQNAQALN TASALGKLQNVVNQNAQALN 203 63
HLA-DRB1*04:02 SALGKLQDVVNQNAQA SALGKLQNVVNQNAQA 1224 381
HLA-DRB1*04:02 GKLQDVVNQNAQALN GKLQNVVNQNAQALN 693 216
HLA-DRB1*08:02 ASALGKLQDVVNQNAQALN ASALGKLQNVVNQNAQALN 1603 500
HLA-DRB1*04:01 GKLQDVVNQNAQALNT GKLQNVVNQNAQALNT 571 179
HLA-DRB1*04:04 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 102 32
HLA-DRB1*04:01 ASALGKLQDVVNQNAQALN ASALGKLQNVVNQNAQALN 624 196
HLA-DRB1*04:02 SALGKLQDVVNQNAQAL SALGKLQNVVNQNAQAL 1163 366
HLA-DRB1*04:01 TASALGKLQDVVNQNAQAL TASALGKLQNVVNQNAQAL 653 206
HLA-DRB1*01:01 TASALGKLQDVVNQNAQAL TASALGKLQNVVNQNAQAL 868 274
HLA-DRB1*04:01 LGKLQDVVNQNAQALNTL LGKLQNVVNQNAQALNTL 1341 424
HLA-DRB1*04:02 ALGKLQDVVNQNAQAL ALGKLQNVVNQNAQAL 981 311
HLA-DRB1*10:01 ALGKLQDVVNQNAQA ALGKLQNVVNQNAQA 318 101
HLA-DRB1*04:04 ASALGKLQDVVNQNAQALNT ASALGKLQNVVNQNAQALNT 195 62
HLA-DRB1*04:04 KLQDVVNQNAQALNT KLQNVVNQNAQALNT 261 83
HLA-DRB1*04:02 ASALGKLQDVVNQNAQALNT ASALGKLQNVVNQNAQALNT 1256 400
HLA-DRB1*13:02 SALGKLQDVVNQNAQA SALGKLQNVVNQNAQA 1017 324
HLA-DRB1*01:02 SALGKLQDVVNQNAQ SALGKLQNVVNQNAQ 1028 328
HLA-DRB1*08:04 LGKLQDVVNQNAQALN LGKLQNVVNQNAQALN 1551 495
HLA-DRB1*08:04 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 842 270
HLA-DRB1*10:01 ASALGKLQDVVNQNAQALN ASALGKLQNVVNQNAQALN 433 139
HLA-DRB1*08:02 SALGKLQDVVNQNAQALNT SALGKLQNVVNQNAQALNT 1542 497
HLA-DRB1*04:04 GKLQDVVNQNAQALNTLVK GKLQNVVNQNAQALNTLVK 447 145
HLA-DRB1*04:01 ASALGKLQDVVNQNA ASALGKLQNVVNQNA 898 292
HLA-DRB1*10:01 SSTASALGKLQDVVN SSTASALGKLQNVVN 902 294
HLA-DRB1*15:01 SALGKLQDVVNQNAQALNT SALGKLQNVVNQNAQALNT 1501 490
HLA-DRB1*04:01 GKLQDVVNQNAQALNTL GKLQNVVNQNAQALNTL 615 201
HLA-DRB1*01:01 ALGKLQDVVNQNAQAL ALGKLQNVVNQNAQAL 575 188
HLA-DRB1*15:01 GKLQDVVNQNAQALN GKLQNVVNQNAQALN 703 230
HLA-DRB1*04:01 SALGKLQDVVNQNAQALNT SALGKLQNVVNQNAQALNT 611 200
HLA-DRB1*10:01 ASALGKLQDVVNQNAQAL ASALGKLQNVVNQNAQAL 1169 383
HLA-DRB1*01:01 LSSTASALGKLQDVVNQNAQ LSSTASALGKLQNVVNQNAQ 766 251
HLA-DRB1*13:02 ASALGKLQDVVNQNAQA ASALGKLQNVVNQNAQA 1221 401
HLA-DRB1*16:01 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 1357 448
HLA-DRB1*08:04 STASALGKLQDVVNQNAQAL STASALGKLQNVVNQNAQAL 1496 494
HLA-DRB1*01:02 ALGKLQDVVNQNAQA ALGKLQNVVNQNAQA 732 242
HLA-DRB1*04:02 ALGKLQDVVNQNAQALN ALGKLQNVVNQNAQALN 1087 360
HLA-DRB1*04:02 SALGKLQDVVNQNAQALNTL SALGKLQNVVNQNAQALNTL 1196 398
HLA-DRB1*04:02 LGKLQDVVNQNAQALN LGKLQNVVNQNAQALN 949 317
HLA-DRB1*01:01 STASALGKLQDVVNQNAQAL STASALGKLQNVVNQNAQAL 425 142
HLA-DRB1*10:01 STASALGKLQDVVNQNAQAL STASALGKLQNVVNQNAQAL 286 96
HLA-DRB1*08:02 STASALGKLQDVVNQNAQAL STASALGKLQNVVNQNAQAL 1135 382
HLA-DRB1*04:04 SALGKLQDVVNQNAQALNTL SALGKLQNVVNQNAQALNTL 187 63
HLA-DRB1*15:01 TASALGKLQDVVNQNAQALN TASALGKLQNVVNQNAQALN 907 306
HLA-DRB1*04:02 LGKLQDVVNQNAQALNT LGKLQNVVNQNAQALNT 1108 375
HLA-DRB1*11:02 SALGKLQDVVNQNAQAL SALGKLQNVVNQNAQAL 1350 457
HLA-DRB1*13:01 SALGKLQDVVNQNAQAL SALGKLQNVVNQNAQAL 1350 457
HLA-DRB1*08:02 TASALGKLQDVVNQNAQALN TASALGKLQNVVNQNAQALN 1045 354
HLA-DRB1*04:02 ALGKLQDVVNQNAQALNTLV ALGKLQNVVNQNAQALNTLV 1236 420
HLA-DRB1*08:04 TASALGKLQDVVNQNAQALN TASALGKLQNVVNQNAQALN 1386 478
HLA-DRB1*04:04 ALGKLQDVVNQNAQALNTLV ALGKLQNVVNQNAQALNTLV 198 69
HLA-DRB1*04:02 GKLQDVVNQNAQALNT GKLQNVVNQNAQALNT 1243 435
HLA-DRB1*04:01 ALGKLQDVVNQNAQALNTL ALGKLQNVVNQNAQALNTL 591 209
HLA-DRB1*13:02 STASALGKLQDVVNQNAQA STASALGKLQNVVNQNAQA 1365 483
HLA-DRB1*04:01 LSSTASALGKLQDVVNQNAQ LSSTASALGKLQNVVNQNAQ 1098 390
HLA-DRB1*10:01 SALGKLQDVVNQNAQALN SALGKLQNVVNQNAQALN 1145 407
HLA-DRB1*04:01 STASALGKLQDVVNQNAQAL STASALGKLQNVVNQNAQAL 478 170
HLA-DRB1*11:02 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 427 152
HLA-DRB1*13:01 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 427 152
HLA-DRB1*11:02 ALGKLQDVVNQNAQAL ALGKLQNVVNQNAQAL 1083 386
HLA-DRB1*13:01 ALGKLQDVVNQNAQAL ALGKLQNVVNQNAQAL 1083 386
HLA-DRB1*08:02 ASALGKLQDVVNQNAQALNT ASALGKLQNVVNQNAQALNT 965 346
HLA-DRB1*08:04 ASALGKLQDVVNQNAQALNT ASALGKLQNVVNQNAQALNT 1302 467
HLA-DRB1*13:02 SSTASALGKLQDVVNQNAQA SSTASALGKLQNVVNQNAQA 815 294
HLA-DRB1*04:04 KLQDVVNQNAQALNTLV KLQNVVNQNAQALNTLV 523 189
HLA-DRB1*04:02 KLQDVVNQNAQALNT KLQNVVNQNAQALNT 973 352
HLA-DRB1*04:02 LGKLQDVVNQNAQALNTLVK LGKLQNVVNQNAQALNTLVK 1289 467
HLA-DRB1*15:01 ASALGKLQDVVNQNAQALNT ASALGKLQNVVNQNAQALNT 764 277
HLA-DRB1*04:04 KLQDVVNQNAQALNTL KLQNVVNQNAQALNTL 433 157
HLA-DRB1*10:01 SLSSTASALGKLQDVVNQNA SLSSTASALGKLQNVVNQNA 397 144
HLA-DRB1*10:01 TASALGKLQDVVNQNAQALN TASALGKLQNVVNQNAQALN 254 93
HLA-DRB1*10:01 SALGKLQDVVNQNAQALNT SALGKLQNVVNQNAQALNT 426 156
HLA-DRB1*04:04 LGKLQDVVNQNAQALNTLVK LGKLQNVVNQNAQALNTLVK 215 79
HLA-DRB1*10:01 ALGKLQDVVNQNAQALN ALGKLQNVVNQNAQALN 378 139
HLA-DRB1*11:02 ALGKLQDVVNQNAQALN ALGKLQNVVNQNAQALN 1019 376
HLA-DRB1*13:01 ALGKLQDVVNQNAQALN ALGKLQNVVNQNAQALN 1019 376
HLA-DRB1*04:01 TASALGKLQDVVNQNAQALN TASALGKLQNVVNQNAQALN 427 158
HLA-DRB1*04:01 LGKLQDVVNQNAQALNTLV LGKLQNVVNQNAQALNTLV 636 237
HLA-DRB1*15:01 ALGKLQDVVNQNAQALNTL ALGKLQNVVNQNAQALNTL 1136 427
HLA-DRB1*08:04 SALGKLQDVVNQNAQALNTL SALGKLQNVVNQNAQALNTL 1233 466
HLA-DRB1*04:04 SLSSTASALGKLQDVVNQNA SLSSTASALGKLQNVVNQNA 992 377
HLA-DRB1*15:01 GKLQDVVNQNAQALNT GKLQNVVNQNAQALNT 1266 482
HLA-DRB1*08:02 KLQDVVNQNAQALNT KLQNVVNQNAQALNT 1197 456
HLA-DRB1*10:01 ALGKLQDVVNQNAQAL ALGKLQNVVNQNAQAL 382 146
HLA-DRB1*01:01 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 182 70
HLA-DRB1*01:01 SSTASALGKLQDVVN SSTASALGKLQNVVN 864 333
HLA-DRB1*04:01 ASALGKLQDVVNQNAQALNT ASALGKLQNVVNQNAQALNT 396 153
HLA-DRB1*10:01 ALGKLQDVVNQNAQALNT ALGKLQNVVNQNAQALNT 1136 441
HLA-DRB1*08:04 ALGKLQDVVNQNAQALNTLV ALGKLQNVVNQNAQALNTLV 1249 491
HLA-DRB1*11:02 LGKLQDVVNQNAQALNT LGKLQNVVNQNAQALNT 835 329
HLA-DRB1*13:01 LGKLQDVVNQNAQALNT LGKLQNVVNQNAQALNT 835 329
HLA-DRB1*11:02 LGKLQDVVNQNAQALN LGKLQNVVNQNAQALN 829 327
HLA-DRB1*13:01 LGKLQDVVNQNAQALN LGKLQNVVNQNAQALN 829 327
HLA-DRB1*15:01 LGKLQDVVNQNAQALNTLV LGKLQNVVNQNAQALNTLV 1164 460
HLA-DRB1*08:02 SALGKLQDVVNQNAQALNTL SALGKLQNVVNQNAQALNTL 879 349
HLA-DRB1*10:01 ASALGKLQDVVNQNAQALNT ASALGKLQNVVNQNAQALNT 236 95
HLA-DRB1*04:03 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 1069 431
HLA-DRB1*01:01 ASALGKLQDVVNQNAQALN ASALGKLQNVVNQNAQALN 519 211
HLA-DRB1*04:01 GKLQDVVNQNAQALNTLVK GKLQNVVNQNAQALNTLVK 798 326
HLA-DRB1*04:01 KLQDVVNQNAQALNT KLQNVVNQNAQALNT 440 180
HLA-DRB1*10:01 SLSSTASALGKLQDVVNQN SLSSTASALGKLQNVVNQN 752 311
HLA-DRB1*04:01 SALGKLQDVVNQNAQALNTL SALGKLQNVVNQNAQALNTL 369 153
HLA-DRB1*04:04 GKLQDVVNQNAQALNTLVKQ GKLQNVVNQNAQALNTLVKQ 281 117
HLA-DRB1*08:02 ALGKLQDVVNQNAQALNTLV ALGKLQNVVNQNAQALNTLV 886 369
HLA-DRB1*15:01 SALGKLQDVVNQNAQALNTL SALGKLQNVVNQNAQALNTL 550 232
HLA-DRB1*11:02 GKLQDVVNQNAQALN GKLQNVVNQNAQALN 339 143
HLA-DRB1*13:01 GKLQDVVNQNAQALN GKLQNVVNQNAQALN 339 143
HLA-DRB1*11:02 STASALGKLQDVVNQNAQAL STASALGKLQNVVNQNAQAL 910 384
HLA-DRB1*13:01 STASALGKLQDVVNQNAQAL STASALGKLQNVVNQNAQAL 910 384
HLA-DRB1*11:02 SALGKLQDVVNQNAQALNT SALGKLQNVVNQNAQALNT 1097 466
HLA-DRB1*13:01 SALGKLQDVVNQNAQALNT SALGKLQNVVNQNAQALNT 1097 466
HLA-DRB1*01:01 ALGKLQDVVNQNAQALN ALGKLQNVVNQNAQALN 343 146
HLA-DRB1*04:01 ALGKLQDVVNQNAQALNTLV ALGKLQNVVNQNAQALNTLV 389 166
HLA-DRB1*15:01 GKLQDVVNQNAQALNTL GKLQNVVNQNAQALNTL 1025 442
HLA-DRB1*13:02 SALGKLQDVVNQNAQAL SALGKLQNVVNQNAQAL 248 107
HLA-DRB1*13:02 ALGKLQDVVNQNAQAL ALGKLQNVVNQNAQAL 222 96
HLA-DRB1*11:02 GKLQDVVNQNAQALNT GKLQNVVNQNAQALNT 744 322
HLA-DRB1*13:01 GKLQDVVNQNAQALNT GKLQNVVNQNAQALNT 744 322
HLA-DRB1*15:02 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 751 326
HLA-DRB1*10:01 GKLQDVVNQNAQALNT GKLQNVVNQNAQALNT 452 197
HLA-DRB1*01:01 TASALGKLQDVVNQNAQALN TASALGKLQNVVNQNAQALN 243 106
HLA-DRB1*10:01 LGKLQDVVNQNAQALNTL LGKLQNVVNQNAQALNTL 1079 471
HLA-DRB1*15:01 ALGKLQDVVNQNAQALNTLV ALGKLQNVVNQNAQALNTLV 534 236
HLA-DRB1*10:01 LGKLQDVVNQNAQALN LGKLQNVVNQNAQALN 373 165
HLA-DRB1*13:02 TASALGKLQDVVNQNAQAL TASALGKLQNVVNQNAQAL 332 147
HLA-DRB1*01:02 SALGKLQDVVNQNAQAL SALGKLQNVVNQNAQAL 941 417
HLA-DRB1*10:01 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 243 108
HLA-DRB1*04:01 KLQDVVNQNAQALNTL KLQNVVNQNAQALNTL 711 316
HLA-DRB1*13:02 ASALGKLQDVVNQNAQAL ASALGKLQNVVNQNAQAL 850 379
HLA-DRB1*01:01 LGKLQDVVNQNAQALN LGKLQNVVNQNAQALN 302 135
HLA-DRB1*04:07 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 968 433
HLA-DRB1*01:02 ALGKLQDVVNQNAQAL ALGKLQNVVNQNAQAL 890 399
HLA-DRB1*10:01 LGKLQDVVNQNAQALNT LGKLQNVVNQNAQALNT 371 167
HLA-DRB1*04:01 LGKLQDVVNQNAQALNTLVK LGKLQNVVNQNAQALNTLVK 419 189
HLA-DRB1*10:01 ALGKLQDVVNQNAQALNTL ALGKLQNVVNQNAQALNTL 375 170
HLA-DRB1*04:01 KLQDVVNQNAQALNTLV KLQNVVNQNAQALNTLV 858 389
HLA-DRB1*11:02 TASALGKLQDVVNQNAQALN TASALGKLQNVVNQNAQALN 639 291
HLA-DRB1*13:01 TASALGKLQDVVNQNAQALN TASALGKLQNVVNQNAQALN 639 291
HLA-DRB1*01:02 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 340 155
HLA-DRB1*01:02 STASALGKLQDVVNQNAQAL STASALGKLQNVVNQNAQAL 1012 463
HLA-DRB1*08:02 LGKLQDVVNQNAQALNTLVK LGKLQNVVNQNAQALNTLVK 855 392
HLA-DRB1*10:01 GKLQDVVNQNAQALN GKLQNVVNQNAQALN 278 128
HLA-DRB1*11:02 ASALGKLQDVVNQNAQALNT ASALGKLQNVVNQNAQALNT 510 235
HLA-DRB1*13:01 ASALGKLQDVVNQNAQALNT ASALGKLQNVVNQNAQALNT 510 235
HLA-DRB1*15:01 KLQDVVNQNAQALNT KLQNVVNQNAQALNT 714 331
HLA-DRB1*11:02 KLQDVVNQNAQALNT KLQNVVNQNAQALNT 289 135
HLA-DRB1*13:01 KLQDVVNQNAQALNT KLQNVVNQNAQALNT 289 135
HLA-DRB1*04:04 KLQDVVNQNAQALNTLVKQ KLQNVVNQNAQALNTLVKQ 663 311
HLA-DRB1*13:02 STASALGKLQDVVNQNAQAL STASALGKLQNVVNQNAQAL 202 95
HLA-DRB1*11:02 GKLQDVVNQNAQALNTL GKLQNVVNQNAQALNTL 614 290
HLA-DRB1*13:01 GKLQDVVNQNAQALNTL GKLQNVVNQNAQALNTL 614 290
HLA-DRB1*15:02 LGKLQDVVNQNAQALN LGKLQNVVNQNAQALN 1017 482
HLA-DRB1*01:01 SLSSTASALGKLQDVVNQNA SLSSTASALGKLQNVVNQNA 525 250
HLA-DRB1*15:01 LGKLQDVVNQNAQALNTLVK LGKLQNVVNQNAQALNTLVK 526 251
HLA-DRB1*13:02 ALGKLQDVVNQNAQALN ALGKLQNVVNQNAQALN 180 86
HLA-DRB1*15:02 GKLQDVVNQNAQALN GKLQNVVNQNAQALN 736 352
HLA-DRB1*07:01 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 817 392
HLA-DRB1*11:02 ALGKLQDVVNQNAQALNTL ALGKLQNVVNQNAQALNTL 794 382
HLA-DRB1*13:01 ALGKLQDVVNQNAQALNTL ALGKLQNVVNQNAQALNTL 794 382
HLA-DRB1*13:02 LGKLQDVVNQNAQAL LGKLQNVVNQNAQAL 89 43
HLA-DRB1*15:02 STASALGKLQDVVNQNAQAL STASALGKLQNVVNQNAQAL 1024 498
HLA-DRB1*13:02 ASALGKLQDVVNQNAQALN ASALGKLQNVVNQNAQALN 226 110
HLA-DRB1*10:01 SALGKLQDVVNQNAQALNTL SALGKLQNVVNQNAQALNTL 209 102
HLA-DRB1*01:01 SALGKLQDVVNQNAQALNT SALGKLQNVVNQNAQALNT 337 166
HLA-DRB1*13:02 LGKLQDVVNQNAQALN LGKLQNVVNQNAQALN 160 79
HLA-DRB1*04:01 GKLQDVVNQNAQALNTLVKQ GKLQNVVNQNAQALNTLVKQ 506 250

N protein

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N

R203M

Reference  GGSQASSRSSSRSRNSSRNSTPGSSRGTSPARMAGNGGDAALALLLLDRLN
           ||||||||||||||||||||||||| |||||||||||||||||||||||||
Mutated    GGSQASSRSSSRSRNSSRNSTPGSSMGTSPARMAGNGCDAALALLLLDRLN

Export table to csv 
Allele Reference peptide Mutated peptide Reference affinity (IC50, nM) Mutated affinity (IC50, nM)
HLA-DRB1*01:01 GSSRGTSPARMAGNG GSSMGTSPARMAGNG 1390 364
HLA-DRB1*01:01 PGSSRGTSPARMAGN PGSSMGTSPARMAGN 1305 345
HLA-DQA1*05:01/DQB1*03:01 RGTSPARMAGNGGDAALALL MGTSPARMAGNGCDAALALL 126 444
HLA-DRB1*01:01 SSRGTSPARMAGNGG SSMGTSPARMAGNGC 1480 429
HLA-DRB1*01:01 TPGSSRGTSPARMAG TPGSSMGTSPARMAG 1312 399
HLA-DQA1*05:01/DQB1*03:01 RGTSPARMAGNGGDAALAL MGTSPARMAGNGCDAALAL 194 625
HLA-DQA1*02:01/DQB1*03:03 STPGSSRGTSPARMAG STPGSSMGTSPARMAG 792 263
HLA-DQA1*02:01/DQB1*03:03 NSTPGSSRGTSPARMAG NSTPGSSMGTSPARMAG 1062 360
HLA-DQA1*02:01/DQB1*03:03 RNSTPGSSRGTSPARMA RNSTPGSSMGTSPARMA 987 337
HLA-DQA1*02:01/DQB1*03:03 NSTPGSSRGTSPARMA NSTPGSSMGTSPARMA 723 256
HLA-DQA1*02:01/DQB1*03:03 RNSTPGSSRGTSPARMAGNG RNSTPGSSMGTSPARMAGNG 783 281
HLA-DQA1*02:01/DQB1*03:03 SRNSTPGSSRGTSPARMAGN SRNSTPGSSMGTSPARMAGN 756 272
HLA-DQA1*02:01/DQB1*03:03 STPGSSRGTSPARMAGN STPGSSMGTSPARMAGN 959 348
HLA-DQA1*02:01/DQB1*03:03 STPGSSRGTSPARMA STPGSSMGTSPARMA 575 210
HLA-DQA1*02:01/DQB1*03:03 NSTPGSSRGTSPARMAGNGG NSTPGSSMGTSPARMAGNGC 800 295
HLA-DQA1*02:01/DQB1*03:03 SSRNSTPGSSRGTSPARMAG SSRNSTPGSSMGTSPARMAG 786 290
HLA-DQA1*02:01/DQB1*03:03 STPGSSRGTSPARMAGNGGD STPGSSMGTSPARMAGNGCD 825 306
HLA-DQA1*02:01/DQB1*03:03 SRNSTPGSSRGTSPARMAG SRNSTPGSSMGTSPARMAG 973 362
HLA-DQA1*02:01/DQB1*03:03 TPGSSRGTSPARMAG TPGSSMGTSPARMAG 635 237
HLA-DQA1*02:01/DQB1*03:03 TPGSSRGTSPARMAGNG TPGSSMGTSPARMAGNG 1021 387
HLA-DQA1*02:01/DQB1*03:03 TPGSSRGTSPARMAGN TPGSSMGTSPARMAGN 706 269
HLA-DQA1*02:01/DQB1*03:03 RNSTPGSSRGTSPARMAGN RNSTPGSSMGTSPARMAGN 924 353
HLA-DQA1*02:01/DQB1*03:03 NSTPGSSRGTSPARMAGNG NSTPGSSMGTSPARMAGNG 953 370
HLA-DQA1*02:01/DQB1*03:03 PGSSRGTSPARMAGNGG PGSSMGTSPARMAGNGC 1081 420
HLA-DQA1*02:01/DQB1*03:03 TPGSSRGTSPARMAGNGGDA TPGSSMGTSPARMAGNGCDA 841 327
HLA-DQA1*06:01/DQB1*03:01 STPGSSRGTSPARMAG STPGSSMGTSPARMAG 618 241
HLA-DQA1*05:01/DQB1*03:01 SRGTSPARMAGNGGDAALAL SMGTSPARMAGNGCDAALAL 146 372
HLA-DQA1*02:01/DQB1*03:03 STPGSSRGTSPARMAGNGG STPGSSMGTSPARMAGNGC 975 385
HLA-DQA1*02:01/DQB1*03:03 PGSSRGTSPARMAGNG PGSSMGTSPARMAGNG 764 302
HLA-DQA1*06:01/DQB1*03:01 TPGSSRGTSPARMAG TPGSSMGTSPARMAG 497 200
HLA-DQA1*02:01/DQB1*03:03 PGSSRGTSPARMAGN PGSSMGTSPARMAGN 610 247
HLA-DQA1*02:01/DQB1*03:03 TPGSSRGTSPARMAGNGGD TPGSSMGTSPARMAGNGCD 1021 415
HLA-DQA1*02:01/DQB1*03:03 NSSRNSTPGSSRGTSPARMA NSSRNSTPGSSMGTSPARMA 744 303
HLA-DQA1*02:01/DQB1*03:03 SSRNSTPGSSRGTSPARMA SSRNSTPGSSMGTSPARMA 882 367
HLA-DQA1*06:01/DQB1*03:01 NSTPGSSRGTSPARMAG NSTPGSSMGTSPARMAG 770 324
HLA-DQA1*06:01/DQB1*03:01 NSTPGSSRGTSPARMA NSTPGSSMGTSPARMA 588 251
HLA-DQA1*06:01/DQB1*03:01 RNSTPGSSRGTSPARMA RNSTPGSSMGTSPARMA 756 323
HLA-DQA1*06:01/DQB1*03:01 PGSSRGTSPARMAGN PGSSMGTSPARMAGN 399 171
HLA-DQA1*02:01/DQB1*03:03 PGSSRGTSPARMAGNGGDA PGSSMGTSPARMAGNGCDA 1057 453
HLA-DQA1*02:01/DQB1*03:03 GSSRGTSPARMAGNGGD GSSMGTSPARMAGNGCD 1047 450
HLA-DQA1*05:01/DQB1*03:01 RNSTPGSSRGTSPAR RNSTPGSSMGTSPAR 644 277
HLA-DQA1*02:01/DQB1*03:03 GSSRGTSPARMAGNGG GSSMGTSPARMAGNGC 772 333
HLA-DQA1*06:01/DQB1*03:01 TPGSSRGTSPARMAGN TPGSSMGTSPARMAGN 481 208
HLA-DQA1*06:01/DQB1*03:01 STPGSSRGTSPARMA STPGSSMGTSPARMA 484 210
HLA-DQA1*05:01/DQB1*03:01 TPGSSRGTSPARMAG TPGSSMGTSPARMAG 333 145
HLA-DQA1*02:01/DQB1*03:03 PGSSRGTSPARMAGNGGDAA PGSSMGTSPARMAGNGCDAA 766 334
HLA-DQA1*06:01/DQB1*03:01 SRNSTPGSSRGTSPARMAG SRNSTPGSSMGTSPARMAG 907 396
HLA-DQA1*06:01/DQB1*03:01 PGSSRGTSPARMAGNG PGSSMGTSPARMAGNG 491 215
HLA-DQA1*01:03/DQB1*06:01 RNSTPGSSRGTSPARMAGN RNSTPGSSMGTSPARMAGN 494 217
HLA-DQA1*05:01/DQB1*03:01 STPGSSRGTSPARMAG STPGSSMGTSPARMAG 416 183
HLA-DQA1*06:01/DQB1*06:01 TPGSSRGTSPARMAG TPGSSMGTSPARMAG 799 352
HLA-DQA1*01:03/DQB1*06:01 TPGSSRGTSPARMAG TPGSSMGTSPARMAG 323 143
HLA-DQA1*06:01/DQB1*06:01 STPGSSRGTSPARMA STPGSSMGTSPARMA 865 384
HLA-DQA1*02:01/DQB1*03:03 GSSRGTSPARMAGNG GSSMGTSPARMAGNG 610 271
HLA-DQA1*01:03/DQB1*06:01 RNSTPGSSRGTSPARMAGNG RNSTPGSSMGTSPARMAGNG 333 148
HLA-DQA1*01:03/DQB1*06:02 SRNSTPGSSRGTSPARMAGN SRNSTPGSSMGTSPARMAGN 1103 491
HLA-DQA1*06:01/DQB1*03:01 GSSRGTSPARMAGNG GSSMGTSPARMAGNG 424 189
HLA-DQA1*01:03/DQB1*06:01 NSTPGSSRGTSPARMAG NSTPGSSMGTSPARMAG 430 194
HLA-DQA1*01:03/DQB1*06:02 RNSTPGSSRGTSPARMAGNG RNSTPGSSMGTSPARMAGNG 974 442
HLA-DQA1*01:03/DQB1*06:01 STPGSSRGTSPARMAG STPGSSMGTSPARMAG 387 176
HLA-DQA1*06:01/DQB1*03:01 NSTPGSSRGTSPARMAGNG NSTPGSSMGTSPARMAGNG 787 358
HLA-DQA1*01:03/DQB1*06:01 SRNSTPGSSRGTSPARMAG SRNSTPGSSMGTSPARMAG 562 256
HLA-DQA1*05:01/DQB1*03:01 NSTPGSSRGTSPARMAG NSTPGSSMGTSPARMAG 484 222
HLA-DQA1*01:03/DQB1*06:01 RNSTPGSSRGTSPARMAG RNSTPGSSMGTSPARMAG 885 406
HLA-DQA1*01:03/DQB1*06:02 TPGSSRGTSPARMAG TPGSSMGTSPARMAG 988 454
HLA-DQA1*06:01/DQB1*06:01 STPGSSRGTSPARMAG STPGSSMGTSPARMAG 921 424
HLA-DQA1*01:03/DQB1*06:01 NSTPGSSRGTSPARMAGNG NSTPGSSMGTSPARMAGNG 462 213
HLA-DQA1*01:03/DQB1*06:01 SSRNSTPGSSRGTSPARMAG SSRNSTPGSSMGTSPARMAG 392 181
HLA-DQA1*06:01/DQB1*03:01 STPGSSRGTSPARMAGN STPGSSMGTSPARMAGN 634 293
HLA-DQA1*06:01/DQB1*03:01 RNSTPGSSRGTSPARMAGN RNSTPGSSMGTSPARMAGN 772 357
HLA-DQA1*05:01/DQB1*03:01 TPGSSRGTSPARMAGNG TPGSSMGTSPARMAGNG 430 199
HLA-DQA1*05:01/DQB1*03:01 STPGSSRGTSPARMA STPGSSMGTSPARMA 328 152
HLA-DQA1*01:03/DQB1*06:01 NSTPGSSRGTSPARMAGNGG NSTPGSSMGTSPARMAGNGC 323 150
HLA-DQA1*01:03/DQB1*06:01 SRNSTPGSSRGTSPARMAGN SRNSTPGSSMGTSPARMAGN 331 154
HLA-DQA1*06:01/DQB1*03:01 GSSRGTSPARMAGNGG GSSMGTSPARMAGNGC 535 250
HLA-DQA1*01:03/DQB1*06:01 PGSSRGTSPARMAGN PGSSMGTSPARMAGN 261 122
HLA-DQA1*02:01/DQB1*03:03 SSRGTSPARMAGNGGD SSMGTSPARMAGNGCD 827 387
HLA-DQA1*06:01/DQB1*03:01 SSRNSTPGSSRGTSPARMAG SSRNSTPGSSMGTSPARMAG 692 324
HLA-DQA1*06:01/DQB1*03:01 TPGSSRGTSPARMAGNG TPGSSMGTSPARMAGNG 644 302
HLA-DQA1*01:03/DQB1*06:01 STPGSSRGTSPARMAGNGG STPGSSMGTSPARMAGNGC 464 218
HLA-DQA1*05:01/DQB1*03:01 STPGSSRGTSPARMAGN STPGSSMGTSPARMAGN 423 199
HLA-DQA1*02:01/DQB1*03:03 SSRGTSPARMAGNGG SSMGTSPARMAGNGC 652 307
HLA-DQA1*05:01/DQB1*03:01 NSTPGSSRGTSPARMA NSTPGSSMGTSPARMA 403 190
HLA-DQA1*05:01/DQB1*03:01 GSSRGTSPARMAGNG GSSMGTSPARMAGNG 273 129
HLA-DQA1*05:01/DQB1*03:01 PGSSRGTSPARMAGNG PGSSMGTSPARMAGNG 338 160
HLA-DQA1*01:02/DQB1*06:01 TPGSSRGTSPARMAG TPGSSMGTSPARMAG 378 179
HLA-DQA1*01:03/DQB1*06:01 STPGSSRGTSPARMAGNGGD STPGSSMGTSPARMAGNGCD 318 151
HLA-DQA1*06:01/DQB1*03:01 STPGSSRGTSPARMAGNGG STPGSSMGTSPARMAGNGC 806 383
HLA-DQA1*05:01/DQB1*06:01 TPGSSRGTSPARMAG TPGSSMGTSPARMAG 812 386
HLA-DQA1*06:01/DQB1*03:01 RGTSPARMAGNGGDAALALL MGTSPARMAGNGCDAALALL 251 528
HLA-DQA1*05:01/DQB1*03:01 PGSSRGTSPARMAGN PGSSMGTSPARMAGN 258 123
HLA-DQA1*02:01/DQB1*03:03 SRGTSPARMAGNGGD SMGTSPARMAGNGCD 950 453
HLA-DQA1*06:01/DQB1*03:01 SSRGTSPARMAGNGG SSMGTSPARMAGNGC 549 262
HLA-DQA1*01:03/DQB1*06:02 NSTPGSSRGTSPARMAGNGG NSTPGSSMGTSPARMAGNGC 948 454
HLA-DQA1*02:01/DQB1*03:03 GSSRGTSPARMAGNGGDAA GSSMGTSPARMAGNGCDAA 960 460
HLA-DQA1*01:03/DQB1*06:02 TPGSSRGTSPARMAGNG TPGSSMGTSPARMAGNG 1023 491
HLA-DQA1*05:01/DQB1*03:01 PGSSRGTSPARMAGNGG PGSSMGTSPARMAGNGC 452 217
HLA-DQA1*01:03/DQB1*06:01 NSTPGSSRGTSPARMAGN NSTPGSSMGTSPARMAGN 706 339
HLA-DQA1*06:01/DQB1*03:01 RNSTPGSSRGTSPARMAGNG RNSTPGSSMGTSPARMAGNG 589 283
HLA-DQA1*05:01/DQB1*03:01 TPGSSRGTSPARMAGN TPGSSMGTSPARMAGN 333 160
HLA-DQA1*01:03/DQB1*06:01 STPGSSRGTSPARMAGN STPGSSMGTSPARMAGN 337 163
HLA-DQA1*01:03/DQB1*06:01 SRGTSPARMAGNGGD SMGTSPARMAGNGCD 405 196
HLA-DQA1*01:03/DQB1*06:01 TPGSSRGTSPARMAGNGGD TPGSSMGTSPARMAGNGCD 448 217
HLA-DQA1*06:01/DQB1*03:01 SSRNSTPGSSRGTSPARMA SSRNSTPGSSMGTSPARMA 871 422
HLA-DQA1*06:01/DQB1*03:01 PGSSRGTSPARMAGNGG PGSSMGTSPARMAGNGC 686 333
HLA-DQA1*06:01/DQB1*03:01 SRGTSPARMAGNGGD SMGTSPARMAGNGCD 805 391
HLA-DQA1*01:03/DQB1*06:01 TPGSSRGTSPARMAGNGGDA TPGSSMGTSPARMAGNGCDA 317 154
HLA-DQA1*05:01/DQB1*03:01 RNSTPGSSRGTSPARMA RNSTPGSSMGTSPARMA 469 228
HLA-DQA1*01:03/DQB1*06:01 PGSSRGTSPARMAGNGGDA PGSSMGTSPARMAGNGCDA 457 223
HLA-DQA1*01:03/DQB1*06:01 STPGSSRGTSPARMA STPGSSMGTSPARMA 348 170
HLA-DQA1*01:02/DQB1*06:01 STPGSSRGTSPARMAG STPGSSMGTSPARMAG 436 213
HLA-DQA1*01:03/DQB1*06:01 TPGSSRGTSPARMAGN TPGSSMGTSPARMAGN 309 151
HLA-DQA1*06:01/DQB1*03:01 RNSTPGSSRGTSPARM RNSTPGSSMGTSPARM 815 399
HLA-DQA1*01:03/DQB1*06:02 TPGSSRGTSPARMAGN TPGSSMGTSPARMAGN 913 447
HLA-DQA1*01:02/DQB1*06:01 SSRNSTPGSSRGTSPARMAG SSRNSTPGSSMGTSPARMAG 398 195
HLA-DQA1*06:01/DQB1*06:01 NSTPGSSRGTSPARMA NSTPGSSMGTSPARMA 1002 491
HLA-DQA1*06:01/DQB1*03:01 SRNSTPGSSRGTSPARMAGN SRNSTPGSSMGTSPARMAGN 582 286
HLA-DQA1*02:01/DQB1*03:03 NSTPGSSRGTSPARM NSTPGSSMGTSPARM 933 459
HLA-DQA1*01:03/DQB1*06:02 PGSSRGTSPARMAGN PGSSMGTSPARMAGN 749 369
HLA-DQA1*01:03/DQB1*06:02 STPGSSRGTSPARMAGNGGD STPGSSMGTSPARMAGNGCD 914 451
HLA-DQA1*06:01/DQB1*03:01 NSTPGSSRGTSPARMAGNGG NSTPGSSMGTSPARMAGNGC 614 303
HLA-DQA1*05:01/DQB1*03:01 RGTSPARMAGNGGDAALA MGTSPARMAGNGCDAALA 491 990
HLA-DQA1*01:02/DQB1*06:02 STPGSSRGTSPARMAGN STPGSSMGTSPARMAGN 1008 500
HLA-DQA1*01:03/DQB1*06:01 GSSRGTSPARMAGNG GSSMGTSPARMAGNG 245 122
HLA-DQA1*01:03/DQB1*06:01 SRGTSPARMAGNGGDA SMGTSPARMAGNGCDA 500 249
HLA-DQA1*05:01/DQB1*06:01 GSSRGTSPARMAGNG GSSMGTSPARMAGNG 697 348
HLA-DQA1*05:01/DQB1*03:01 SRNSTPGSSRGTSPAR SRNSTPGSSMGTSPAR 775 387
HLA-DQA1*01:03/DQB1*06:01 PGSSRGTSPARMAGNG PGSSMGTSPARMAGNG 292 146

G215C

Reference  SRNSSRNSTPGSSRGTSPARMAGNGGDAALALLLLDRLNQLESKMSGKGQQ
           ||||||||||||||||||||||||| |||||||||||||||||||||||||
Mutated    SRNSSRNSTPGSSMGTSPARMAGNGCDAALALLLLDRLNQLESKMSGKGQQ

Export table to csv 
Allele Reference peptide Mutated peptide Reference affinity (IC50, nM) Mutated affinity (IC50, nM)
HLA-DQA1*05:01/DQB1*03:01 ARMAGNGGDAALALL ARMAGNGCDAALALL 58 423
HLA-DQA1*05:01/DQB1*03:01 RMAGNGGDAALALLL RMAGNGCDAALALLL 54 360
HLA-DQA1*05:01/DQB1*03:01 PARMAGNGGDAALAL PARMAGNGCDAALAL 70 438
HLA-DQA1*05:01/DQB1*03:01 SPARMAGNGGDAALALL SPARMAGNGCDAALALL 99 610
HLA-DQA1*05:01/DQB1*03:01 PARMAGNGGDAALALLL PARMAGNGCDAALALLL 86 522
HLA-DQA1*05:01/DQB1*03:01 PARMAGNGGDAALALL PARMAGNGCDAALALL 75 449
HLA-DQA1*05:01/DQB1*03:01 ARMAGNGGDAALALLLL ARMAGNGCDAALALLLL 88 524
HLA-DQA1*05:01/DQB1*03:01 ARMAGNGGDAALALLL ARMAGNGCDAALALLL 66 387
HLA-DQA1*05:01/DQB1*03:01 RMAGNGGDAALALLLL RMAGNGCDAALALLLL 71 407
HLA-DQA1*05:01/DQB1*03:01 MAGNGGDAALALLLL MAGNGCDAALALLLL 72 412
HLA-DQA1*05:01/DQB1*03:01 RMAGNGGDAALALLLLD RMAGNGCDAALALLLLD 95 534
HLA-DQA1*05:01/DQB1*03:01 SPARMAGNGGDAALALLL SPARMAGNGCDAALALLL 161 890
HLA-DQA1*05:01/DQB1*03:01 PARMAGNGGDAALALLLL PARMAGNGCDAALALLLL 164 897
HLA-DPA1*03:01/DPB1*02:01 RMAGNGGDAALALLL RMAGNGCDAALALLL 2240 416
HLA-DQA1*05:01/DQB1*03:01 TSPARMAGNGGDAALAL TSPARMAGNGCDAALAL 121 645
HLA-DQA1*05:01/DQB1*03:01 SPARMAGNGGDAALAL SPARMAGNGCDAALAL 92 489
HLA-DQA1*05:01/DQB1*03:01 TSPARMAGNGGDAALALL TSPARMAGNGCDAALALL 197 1038
HLA-DQA1*05:01/DQB1*03:01 ARMAGNGGDAALALLLLD ARMAGNGCDAALALLLLD 171 873
HLA-DQA1*05:01/DQB1*03:01 SPARMAGNGGDAALALLLL SPARMAGNGCDAALALLLL 143 702
HLA-DQA1*05:01/DQB1*03:01 TSPARMAGNGGDAALALLL TSPARMAGNGCDAALALLL 142 691
HLA-DQA1*05:01/DQB1*03:01 GTSPARMAGNGGDAALALL GTSPARMAGNGCDAALALL 158 744
HLA-DQA1*05:01/DQB1*03:01 PARMAGNGGDAALALLLLD PARMAGNGCDAALALLLLD 147 687
HLA-DQA1*05:01/DQB1*03:01 RMAGNGGDAALALLLLDR RMAGNGCDAALALLLLDR 186 859
HLA-DRB1*07:01 GNGGDAALALLLLDR GNGCDAALALLLLDR 893 195
HLA-DQA1*05:01/DQB1*03:01 TSPARMAGNGGDAALALLLL TSPARMAGNGCDAALALLLL 116 526
HLA-DQA1*05:01/DQB1*03:01 MAGNGGDAALALLLLD MAGNGCDAALALLLLD 102 462
HLA-DQA1*05:01/DQB1*03:01 SPARMAGNGGDAALA SPARMAGNGCDAALA 116 505
HLA-DQA1*05:01/DQB1*03:01 SPARMAGNGGDAALALLLLD SPARMAGNGCDAALALLLLD 121 526
HLA-DQA1*05:01/DQB1*03:01 GTSPARMAGNGGDAALALLL GTSPARMAGNGCDAALALLL 114 492
HLA-DRB1*07:01 AGNGGDAALALLLLD AGNGCDAALALLLLD 1184 279
HLA-DQA1*05:01/DQB1*03:01 GTSPARMAGNGGDAALAL GTSPARMAGNGCDAALAL 264 1106
HLA-DQA1*05:01/DQB1*03:01 MAGNGGDAALALLLLDR MAGNGCDAALALLLLDR 135 565
HLA-DRB1*07:01 MAGNGGDAALALLLLDR MAGNGCDAALALLLLDR 1926 466
HLA-DQA1*05:01/DQB1*03:01 ARMAGNGGDAALALLLLDR ARMAGNGCDAALALLLLDR 153 630
HLA-DQA1*05:01/DQB1*03:01 RMAGNGGDAALALLLLDRL RMAGNGCDAALALLLLDRL 172 703
HLA-DQA1*05:01/DQB1*03:01 AGNGGDAALALLLLD AGNGCDAALALLLLD 110 446
HLA-DQA1*05:01/DQB1*03:01 MAGNGGDAALALLLLDRL MAGNGCDAALALLLLDRL 284 1144
HLA-DRB1*07:01 RMAGNGGDAALALLL RMAGNGCDAALALLL 1375 343
HLA-DQA1*05:01/DQB1*03:01 ARMAGNGGDAALALLLLDRL ARMAGNGCDAALALLLLDRL 135 536
HLA-DQA1*05:01/DQB1*03:01 RMAGNGGDAALALLLLDRLN RMAGNGCDAALALLLLDRLN 157 617
HLA-DQA1*05:01/DQB1*03:01 PARMAGNGGDAALALLLLDR PARMAGNGCDAALALLLLDR 125 491
HLA-DQA1*05:01/DQB1*03:01 TSPARMAGNGGDAALA TSPARMAGNGCDAALA 153 576
HLA-DQA1*06:01/DQB1*03:01 ARMAGNGGDAALALL ARMAGNGCDAALALL 145 544
HLA-DQA1*05:01/DQB1*03:01 MAGNGGDAALALLLLDRLN MAGNGCDAALALLLLDRLN 266 967
HLA-DQA1*05:01/DQB1*03:01 MAGNGGDAALALLLLDRLNQ MAGNGCDAALALLLLDRLNQ 244 877
HLA-DQA1*05:01/DQB1*03:01 GTSPARMAGNGGDAALA GTSPARMAGNGCDAALA 198 705
HLA-DRB1*07:01 AGNGGDAALALLLLDRL AGNGCDAALALLLLDRL 1739 490
HLA-DQA1*05:01/DQB1*03:01 RGTSPARMAGNGGDAALALL MGTSPARMAGNGCDAALALL 126 444
HLA-DPA1*03:01/DPB1*01:01 RMAGNGGDAALALLL RMAGNGCDAALALLL 1281 365
HLA-DRB1*01:01 AGNGGDAALALLLLDR AGNGCDAALALLLLDR 667 192
HLA-DRB1*01:01 SSRGTSPARMAGNGG SSMGTSPARMAGNGC 1480 429
HLA-DRB1*07:01 MAGNGGDAALALLLL MAGNGCDAALALLLL 960 282
HLA-DQA1*06:01/DQB1*03:01 PARMAGNGGDAALAL PARMAGNGCDAALAL 176 593
HLA-DPA1*03:01/DPB1*01:01 PARMAGNGGDAALALLL PARMAGNGCDAALALLL 1458 437
HLA-DRB1*01:01 MAGNGGDAALALLLLDR MAGNGCDAALALLLLDR 475 143
HLA-DRB1*01:01 GNGGDAALALLLLDR GNGCDAALALLLLDR 155 47
HLA-DQA1*06:01/DQB1*03:01 RMAGNGGDAALALLL RMAGNGCDAALALLL 129 422
HLA-DRB1*01:01 MAGNGGDAALALLLLD MAGNGCDAALALLLLD 1075 332
HLA-DPA1*03:01/DPB1*01:01 ARMAGNGGDAALALLL ARMAGNGCDAALALLL 1454 451
HLA-DRB1*07:01 NGGDAALALLLLDRL NGCDAALALLLLDRL 854 265
HLA-DQA1*05:01/DQB1*03:01 RGTSPARMAGNGGDAALAL MGTSPARMAGNGCDAALAL 194 625
HLA-DQA1*05:01/DQB1*03:01 AGNGGDAALALLLLDRL AGNGCDAALALLLLDRL 222 715
HLA-DQA1*06:01/DQB1*03:01 SPARMAGNGGDAALALL SPARMAGNGCDAALALL 241 776
HLA-DRB1*01:01 RMAGNGGDAALALLLLD RMAGNGCDAALALLLLD 774 242
HLA-DQA1*06:01/DQB1*03:01 PARMAGNGGDAALALL PARMAGNGCDAALALL 175 556
HLA-DRB1*01:01 AGNGGDAALALLLLD AGNGCDAALALLLLD 242 77
HLA-DQA1*05:01/DQB1*03:01 AGNGGDAALALLLLDR AGNGCDAALALLLLDR 156 482
HLA-DQA1*06:01/DQB1*03:01 TSPARMAGNGGDAALALL TSPARMAGNGCDAALALL 400 1208
HLA-DQA1*05:01/DQB1*03:01 AGNGGDAALALLLLDRLN AGNGCDAALALLLLDRLN 487 1451
HLA-DQA1*06:01/DQB1*03:01 GTSPARMAGNGGDAALALL GTSPARMAGNGCDAALALL 315 938
HLA-DQA1*06:01/DQB1*03:01 TSPARMAGNGGDAALAL TSPARMAGNGCDAALAL 280 826
HLA-DQA1*06:01/DQB1*03:01 ARMAGNGGDAALALLLL ARMAGNGCDAALALLLL 208 611
HLA-DQA1*06:01/DQB1*03:01 PARMAGNGGDAALALLLL PARMAGNGCDAALALLLL 334 980
HLA-DQA1*06:01/DQB1*03:01 PARMAGNGGDAALALLL PARMAGNGCDAALALLL 205 600
HLA-DRB1*01:01 RMAGNGGDAALALLL RMAGNGCDAALALLL 454 156
HLA-DQA1*06:01/DQB1*03:01 SPARMAGNGGDAALALLL SPARMAGNGCDAALALLL 334 972
HLA-DQA1*06:01/DQB1*03:01 SPARMAGNGGDAALAL SPARMAGNGCDAALAL 212 613
HLA-DQA1*06:01/DQB1*03:01 MAGNGGDAALALLLL MAGNGCDAALALLLL 160 462
HLA-DQA1*06:01/DQB1*03:01 RMAGNGGDAALALLLLD RMAGNGCDAALALLLLD 221 637
HLA-DQA1*06:01/DQB1*03:01 TSPARMAGNGGDAALALLL TSPARMAGNGCDAALALLL 279 804
HLA-DQA1*06:01/DQB1*03:01 ARMAGNGGDAALALLLLD ARMAGNGCDAALALLLLD 344 979
HLA-DQA1*06:01/DQB1*03:01 SPARMAGNGGDAALALLLL SPARMAGNGCDAALALLLL 293 833
HLA-DQA1*06:01/DQB1*03:01 SPARMAGNGGDAALA SPARMAGNGCDAALA 252 715
HLA-DQA1*06:01/DQB1*03:01 TSPARMAGNGGDAALALLLL TSPARMAGNGCDAALALLLL 229 647
HLA-DQA1*05:01/DQB1*03:01 AGNGGDAALALLLLDRLNQL AGNGCDAALALLLLDRLNQL 416 1172
HLA-DRB1*01:01 GNGGDAALALLLLDRL GNGCDAALALLLLDRL 529 188
HLA-DRB1*01:01 RMAGNGGDAALALLLL RMAGNGCDAALALLLL 919 327
HLA-DRB1*01:01 ARMAGNGGDAALALLLL ARMAGNGCDAALALLLL 731 263
HLA-DQA1*05:01/DQB1*03:01 AGNGGDAALALLLLDRLNQ AGNGCDAALALLLLDRLNQ 448 1241
HLA-DRB1*01:01 AGNGGDAALALLLLDRL AGNGCDAALALLLLDRL 377 138
HLA-DRB1*01:02 AGNGGDAALALLLLD AGNGCDAALALLLLD 1081 397
HLA-DQA1*06:01/DQB1*03:01 GTSPARMAGNGGDAALALLL GTSPARMAGNGCDAALALLL 222 604
HLA-DQA1*06:01/DQB1*03:01 RMAGNGGDAALALLLL RMAGNGCDAALALLLL 161 437
HLA-DQA1*02:01/DQB1*03:03 NSTPGSSRGTSPARMAGNGG NSTPGSSMGTSPARMAGNGC 800 295
HLA-DQA1*06:01/DQB1*03:01 ARMAGNGGDAALALLL ARMAGNGCDAALALLL 152 411
HLA-DQA1*06:01/DQB1*03:01 PARMAGNGGDAALALLLLD PARMAGNGCDAALALLLLD 297 802
HLA-DQA1*02:01/DQB1*03:03 STPGSSRGTSPARMAGNGGD STPGSSMGTSPARMAGNGCD 825 306
HLA-DQA1*06:01/DQB1*03:01 SPARMAGNGGDAALALLLLD SPARMAGNGCDAALALLLLD 247 665
HLA-DRB1*01:01 ARMAGNGGDAALALLLLDR ARMAGNGCDAALALLLLDR 747 278
HLA-DRB1*01:02 GNGGDAALALLLLDR GNGCDAALALLLLDR 639 238
HLA-DRB1*01:01 PARMAGNGGDAALALLL PARMAGNGCDAALALLL 1246 466
HLA-DRB1*01:01 MAGNGGDAALALLLL MAGNGCDAALALLLL 234 89
HLA-DQA1*06:01/DQB1*03:01 RMAGNGGDAALALLLLDR RMAGNGCDAALALLLLDR 361 948
HLA-DRB1*01:02 MAGNGGDAALALLLL MAGNGCDAALALLLL 1129 434
HLA-DQA1*02:01/DQB1*03:03 PGSSRGTSPARMAGNGG PGSSMGTSPARMAGNGC 1081 420
HLA-DQA1*02:01/DQB1*03:03 TPGSSRGTSPARMAGNGGDA TPGSSMGTSPARMAGNGCDA 841 327
HLA-DQA1*05:01/DQB1*03:01 SRGTSPARMAGNGGDAALAL SMGTSPARMAGNGCDAALAL 146 372
HLA-DQA1*02:01/DQB1*03:03 STPGSSRGTSPARMAGNGG STPGSSMGTSPARMAGNGC 975 385
HLA-DQA1*04:01/DQB1*03:01 ARMAGNGGDAALALL ARMAGNGCDAALALL 231 580
HLA-DQA1*06:01/DQB1*03:01 PARMAGNGGDAALALLLLDR PARMAGNGCDAALALLLLDR 251 628
HLA-DRB1*01:01 GNGGDAALALLLLDRLN GNGCDAALALLLLDRLN 343 138
HLA-DRB1*01:01 RMAGNGGDAALALLLLDRL RMAGNGCDAALALLLLDRL 650 262
HLA-DQA1*06:01/DQB1*03:01 ARMAGNGGDAALALLLLDRL ARMAGNGCDAALALLLLDRL 266 658
HLA-DQA1*02:01/DQB1*03:03 TPGSSRGTSPARMAGNGGD TPGSSMGTSPARMAGNGCD 1021 415
HLA-DQA1*06:01/DQB1*03:01 ARMAGNGGDAALALLLLDR ARMAGNGCDAALALLLLDR 304 747
HLA-DQA1*06:01/DQB1*03:01 RMAGNGGDAALALLLLDRLN RMAGNGCDAALALLLLDRLN 299 732
HLA-DQA1*06:01/DQB1*03:01 MAGNGGDAALALLLLDR MAGNGCDAALALLLLDR 279 678
HLA-DQA1*06:01/DQB1*03:01 RMAGNGGDAALALLLLDRL RMAGNGCDAALALLLLDRL 338 816
HLA-DRB1*01:01 NGGDAALALLLLDRL NGCDAALALLLLDRL 134 56
HLA-DRB1*10:01 RMAGNGGDAALALLL RMAGNGCDAALALLL 1090 456
HLA-DRB1*01:01 NGGDAALALLLLDRLN NGCDAALALLLLDRLN 491 206
HLA-DQA1*06:01/DQB1*03:01 TSPARMAGNGGDAALA TSPARMAGNGCDAALA 304 721
HLA-DQA1*06:01/DQB1*03:01 MAGNGGDAALALLLLDRL MAGNGCDAALALLLLDRL 479 1131
HLA-DQA1*06:01/DQB1*03:01 AGNGGDAALALLLLD AGNGCDAALALLLLD 231 544
HLA-DQA1*04:01/DQB1*03:01 TSPARMAGNGGDAALALL TSPARMAGNGCDAALALL 406 952
HLA-DQA1*02:01/DQB1*03:03 PGSSRGTSPARMAGNGGDA PGSSMGTSPARMAGNGCDA 1057 453
HLA-DQA1*06:01/DQB1*03:01 GTSPARMAGNGGDAALA GTSPARMAGNGCDAALA 408 951
HLA-DRB1*01:01 MAGNGGDAALALLLLDRLN MAGNGCDAALALLLLDRLN 626 269
HLA-DQA1*02:01/DQB1*03:03 GSSRGTSPARMAGNGGD GSSMGTSPARMAGNGCD 1047 450
HLA-DQA1*02:01/DQB1*03:03 GSSRGTSPARMAGNGG GSSMGTSPARMAGNGC 772 333
HLA-DQA1*06:01/DQB1*03:01 MAGNGGDAALALLLLD MAGNGCDAALALLLLD 205 472
HLA-DQA1*02:01/DQB1*03:03 PGSSRGTSPARMAGNGGDAA PGSSMGTSPARMAGNGCDAA 766 334
HLA-DQA1*04:01/DQB1*03:01 MAGNGGDAALALLLL MAGNGCDAALALLLL 244 559
HLA-DQA1*04:01/DQB1*03:01 PARMAGNGGDAALALL PARMAGNGCDAALALL 236 540
HLA-DQA1*04:01/DQB1*03:01 PARMAGNGGDAALAL PARMAGNGCDAALAL 268 611
HLA-DRB1*01:01 PARMAGNGGDAALALLLLDR PARMAGNGCDAALALLLLDR 445 196
HLA-DQA1*04:01/DQB1*03:01 RMAGNGGDAALALLL RMAGNGCDAALALLL 208 468
HLA-DQA1*06:01/DQB1*03:01 MAGNGGDAALALLLLDRLNQ MAGNGCDAALALLLLDRLNQ 410 919
HLA-DQA1*04:01/DQB1*03:01 SPARMAGNGGDAALALL SPARMAGNGCDAALALL 327 726
HLA-DQA1*06:01/DQB1*03:01 MAGNGGDAALALLLLDRLN MAGNGCDAALALLLLDRLN 453 998
HLA-DRB1*01:01 ARMAGNGGDAALALLLLDRL ARMAGNGCDAALALLLLDRL 422 192
HLA-DQA1*04:01/DQB1*03:01 PARMAGNGGDAALALLLL PARMAGNGCDAALALLLL 344 752
HLA-DRB1*01:01 AGNGGDAALALLLLDRLNQ AGNGCDAALALLLLDRLNQ 587 270
HLA-DQA1*04:01/DQB1*03:01 RMAGNGGDAALALLLLD RMAGNGCDAALALLLLD 277 601
HLA-DQA1*04:01/DQB1*03:01 RMAGNGGDAALALLLL RMAGNGCDAALALLLL 219 474
HLA-DQA1*04:01/DQB1*03:01 SPARMAGNGGDAALALLL SPARMAGNGCDAALALLL 343 741
HLA-DQA1*06:01/DQB1*03:01 AGNGGDAALALLLLDRL AGNGCDAALALLLLDRL 404 872
HLA-DQA1*04:01/DQB1*03:01 RMAGNGGDAALALLLLDR RMAGNGCDAALALLLLDR 337 727
HLA-DQA1*01:03/DQB1*06:01 NSTPGSSRGTSPARMAGNGG NSTPGSSMGTSPARMAGNGC 323 150
HLA-DRB1*01:01 RMAGNGGDAALALLLLDRLN RMAGNGCDAALALLLLDRLN 408 190
HLA-DQA1*04:01/DQB1*03:01 MAGNGGDAALALLLLD MAGNGCDAALALLLLD 233 499
HLA-DQA1*06:01/DQB1*03:01 GSSRGTSPARMAGNGG GSSMGTSPARMAGNGC 535 250
HLA-DQA1*02:01/DQB1*03:03 SSRGTSPARMAGNGGD SSMGTSPARMAGNGCD 827 387
HLA-DQA1*01:03/DQB1*06:01 STPGSSRGTSPARMAGNGG STPGSSMGTSPARMAGNGC 464 218
HLA-DQA1*02:01/DQB1*03:03 SSRGTSPARMAGNGG SSMGTSPARMAGNGC 652 307
HLA-DQA1*04:01/DQB1*03:01 ARMAGNGGDAALALLLLD ARMAGNGCDAALALLLLD 335 711
HLA-DQA1*01:03/DQB1*06:01 STPGSSRGTSPARMAGNGGD STPGSSMGTSPARMAGNGCD 318 151
HLA-DQA1*06:01/DQB1*03:01 STPGSSRGTSPARMAGNGG STPGSSMGTSPARMAGNGC 806 383
HLA-DQA1*06:01/DQB1*03:01 RGTSPARMAGNGGDAALALL MGTSPARMAGNGCDAALALL 251 528
HLA-DQA1*04:01/DQB1*03:01 ARMAGNGGDAALALLLL ARMAGNGCDAALALLLL 287 603
HLA-DQA1*02:01/DQB1*03:03 SRGTSPARMAGNGGD SMGTSPARMAGNGCD 950 453
HLA-DQA1*06:01/DQB1*03:01 SSRGTSPARMAGNGG SSMGTSPARMAGNGC 549 262
HLA-DQA1*01:03/DQB1*06:02 NSTPGSSRGTSPARMAGNGG NSTPGSSMGTSPARMAGNGC 948 454
HLA-DQA1*02:01/DQB1*03:03 GSSRGTSPARMAGNGGDAA GSSMGTSPARMAGNGCDAA 960 460
HLA-DQA1*04:01/DQB1*03:01 PARMAGNGGDAALALLL PARMAGNGCDAALALLL 280 584
HLA-DQA1*05:01/DQB1*03:01 PGSSRGTSPARMAGNGG PGSSMGTSPARMAGNGC 452 217
HLA-DQA1*04:01/DQB1*03:01 MAGNGGDAALALLLLDR MAGNGCDAALALLLLDR 317 660
HLA-DQA1*04:01/DQB1*03:01 SPARMAGNGGDAALAL SPARMAGNGCDAALAL 277 576
HLA-DQA1*01:03/DQB1*06:01 SRGTSPARMAGNGGD SMGTSPARMAGNGCD 405 196
HLA-DQA1*01:03/DQB1*06:01 TPGSSRGTSPARMAGNGGD TPGSSMGTSPARMAGNGCD 448 217
HLA-DQA1*06:01/DQB1*03:01 PGSSRGTSPARMAGNGG PGSSMGTSPARMAGNGC 686 333
HLA-DQA1*06:01/DQB1*03:01 SRGTSPARMAGNGGD SMGTSPARMAGNGCD 805 391
HLA-DQA1*01:03/DQB1*06:01 TPGSSRGTSPARMAGNGGDA TPGSSMGTSPARMAGNGCDA 317 154
HLA-DQA1*04:01/DQB1*03:01 GTSPARMAGNGGDAALAL GTSPARMAGNGCDAALAL 490 1006
HLA-DRB1*01:01 MAGNGGDAALALLLLDRLNQ MAGNGCDAALALLLLDRLNQ 394 192
HLA-DQA1*04:01/DQB1*03:01 TSPARMAGNGGDAALALLLL TSPARMAGNGCDAALALLLL 407 835
HLA-DQA1*01:03/DQB1*06:01 PGSSRGTSPARMAGNGGDA PGSSMGTSPARMAGNGCDA 457 223
HLA-DQA1*04:01/DQB1*03:01 MAGNGGDAALALLLLDRL MAGNGCDAALALLLLDRL 415 850
HLA-DQA1*04:01/DQB1*03:01 ARMAGNGGDAALALLL ARMAGNGCDAALALLL 208 426
HLA-DRB1*01:01 NGGDAALALLLLDRLNQ NGCDAALALLLLDRLNQ 325 159
HLA-DQA1*04:01/DQB1*03:01 AGNGGDAALALLLLD AGNGCDAALALLLLD 303 619
HLA-DQA1*04:01/DQB1*03:01 SPARMAGNGGDAALALLLLD SPARMAGNGCDAALALLLLD 401 816
HLA-DQA1*01:03/DQB1*06:02 STPGSSRGTSPARMAGNGGD STPGSSMGTSPARMAGNGCD 914 451
HLA-DQA1*06:01/DQB1*03:01 NSTPGSSRGTSPARMAGNGG NSTPGSSMGTSPARMAGNGC 614 303
HLA-DRB1*01:01 SPARMAGNGGDAALALLLLD SPARMAGNGCDAALALLLLD 717 355
HLA-DQA1*05:01/DQB1*03:01 RGTSPARMAGNGGDAALA MGTSPARMAGNGCDAALA 491 990
HLA-DRB1*10:01 RMAGNGGDAALALLLLD RMAGNGCDAALALLLLD 881 437
HLA-DRB1*01:01 GNGGDAALALLLLDRLNQL GNGCDAALALLLLDRLNQL 547 272
HLA-DQA1*04:01/DQB1*03:01 RMAGNGGDAALALLLLDRLN RMAGNGCDAALALLLLDRLN 464 933
HLA-DQA1*01:03/DQB1*06:01 SRGTSPARMAGNGGDA SMGTSPARMAGNGCDA 500 249
HLA-DPA1*03:01/DPB1*02:01 MAGNGGDAALALLLL MAGNGCDAALALLLL 418 209

M protein

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M

I82T

Reference  LWPVTLACFVLAAVYRINWITGGIAIAMACLVGLMWLSYFIASFRLFARTR
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Mutated    LWPVTLACFVLAAVYRINWITGGIATAMACLVGLMWLSYFIASFRLFARTR

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Allele Reference peptide Mutated peptide Reference affinity (IC50, nM) Mutated affinity (IC50, nM)
HLA-DQA1*01:02/DQB1*06:02 RINWITGGIAIAMAC RINWITGGIATAMAC 57 174
HLA-DRB1*07:01 RINWITGGIAIAMAC RINWITGGIATAMAC 96 276
HLA-DQA1*01:02/DQB1*06:02 YRINWITGGIAIAMA YRINWITGGIATAMA 54 151
HLA-DQA1*01:02/DQB1*06:02 INWITGGIAIAMACL INWITGGIATAMACL 54 151
HLA-DQA1*01:02/DQB1*06:02 NWITGGIAIAMACLV NWITGGIATAMACLV 55 153
HLA-DQA1*01:02/DQB1*06:02 AVYRINWITGGIAIAMAC AVYRINWITGGIATAMAC 145 391
HLA-DQA1*01:02/DQB1*06:02 VYRINWITGGIAIAMAC VYRINWITGGIATAMAC 75 201
HLA-DQA1*01:02/DQB1*06:02 YRINWITGGIAIAMAC YRINWITGGIATAMAC 62 165
HLA-DRB1*07:01 YRINWITGGIAIAMA YRINWITGGIATAMA 57 149
HLA-DRB1*07:01 YRINWITGGIAIAMAC YRINWITGGIATAMAC 136 353
HLA-DRB1*07:01 RINWITGGIAIAMACL RINWITGGIATAMACL 207 534
HLA-DQA1*01:02/DQB1*06:02 VYRINWITGGIAIAMA VYRINWITGGIATAMA 57 146
HLA-DQA1*01:02/DQB1*06:02 AAVYRINWITGGIAIAMA AAVYRINWITGGIATAMA 132 338
HLA-DQA1*01:02/DQB1*06:02 RINWITGGIAIAMACLVG RINWITGGIATAMACLVG 129 329
HLA-DQA1*01:02/DQB1*06:02 AVYRINWITGGIAIAMA AVYRINWITGGIATAMA 73 186
HLA-DRB1*07:01 YRINWITGGIAIAMACL YRINWITGGIATAMACL 124 312
HLA-DQA1*01:02/DQB1*06:02 INWITGGIAIAMACLVG INWITGGIATAMACLVG 70 172
HLA-DQA1*01:02/DQB1*06:02 YRINWITGGIAIAMACLV YRINWITGGIATAMACLV 121 297
HLA-DQA1*01:02/DQB1*06:02 NWITGGIAIAMACLVGLM NWITGGIATAMACLVGLM 169 414
HLA-DQA1*01:02/DQB1*06:02 NWITGGIAIAMACLVG NWITGGIATAMACLVG 71 173
HLA-DQA1*01:02/DQB1*06:02 NWITGGIAIAMACLVGL NWITGGIATAMACLVGL 82 199
HLA-DQA1*01:02/DQB1*06:02 INWITGGIAIAMACLVGL INWITGGIATAMACLVGL 142 344
HLA-DQA1*01:02/DQB1*06:02 VYRINWITGGIAIAMACL VYRINWITGGIATAMACL 131 317
HLA-DQA1*01:02/DQB1*06:02 RINWITGGIAIAMACLV RINWITGGIATAMACLV 64 154
HLA-DQA1*01:02/DQB1*06:02 YRINWITGGIAIAMACL YRINWITGGIATAMACL 69 166
HLA-DQA1*01:02/DQB1*06:02 RINWITGGIAIAMACL RINWITGGIATAMACL 60 143
HLA-DRB1*07:01 VYRINWITGGIAIAMA VYRINWITGGIATAMA 105 250
HLA-DRB1*07:01 YRINWITGGIAIAMACLV YRINWITGGIATAMACLV 447 1057
HLA-DQA1*01:02/DQB1*06:02 WITGGIAIAMACLVG WITGGIATAMACLVG 90 210
HLA-DRB1*07:01 VYRINWITGGIAIAMACL VYRINWITGGIATAMACL 381 885
HLA-DQA1*01:02/DQB1*06:02 AAVYRINWITGGIAIAMAC AAVYRINWITGGIATAMAC 136 314
HLA-DQA1*01:02/DQB1*06:02 INWITGGIAIAMACLV INWITGGIATAMACLV 59 136
HLA-DQA1*01:02/DQB1*05:01 ITGGIAIAMACLVGL ITGGIATAMACLVGL 93 213
HLA-DRB1*07:01 VYRINWITGGIAIAMAC VYRINWITGGIATAMAC 107 245
HLA-DRB1*07:01 AVYRINWITGGIAIAMAC AVYRINWITGGIATAMAC 352 805
HLA-DQA1*06:01/DQB1*03:01 GGIAIAMACLVGLMW GGIATAMACLVGLMW 612 268
HLA-DRB1*07:01 INWITGGIAIAMACL INWITGGIATAMACL 208 474
HLA-DRB1*07:01 AVYRINWITGGIAIAMA AVYRINWITGGIATAMA 91 207
HLA-DQA1*01:02/DQB1*05:01 WITGGIAIAMACLVGL WITGGIATAMACLVGL 73 166
HLA-DRB1*07:01 AAVYRINWITGGIAIAMA AAVYRINWITGGIATAMA 311 703
HLA-DQA1*01:03/DQB1*06:02 YRINWITGGIAIAMA YRINWITGGIATAMA 63 142
HLA-DRB1*13:02 RINWITGGIAIAMAC RINWITGGIATAMAC 211 458
HLA-DQA1*01:03/DQB1*06:02 RINWITGGIAIAMAC RINWITGGIATAMAC 72 156
HLA-DQA1*01:02/DQB1*06:02 LAAVYRINWITGGIAIAMA LAAVYRINWITGGIATAMA 126 273
HLA-DQA1*01:02/DQB1*05:03 NWITGGIAIAMACLV NWITGGIATAMACLV 266 575
HLA-DQA1*01:02/DQB1*05:03 ITGGIAIAMACLVGL ITGGIATAMACLVGL 386 834
HLA-DQA1*01:02/DQB1*05:01 NWITGGIAIAMACLVGLM NWITGGIATAMACLVGLM 141 301
HLA-DRB1*07:01 AVYRINWITGGIAIAM AVYRINWITGGIATAM 115 244
HLA-DRB1*13:02 INWITGGIAIAMACL INWITGGIATAMACL 437 927
HLA-DQA1*06:01/DQB1*03:01 GIAIAMACLVGLMWL GIATAMACLVGLMWL 972 461
HLA-DQA1*01:02/DQB1*05:01 NWITGGIAIAMACLVGL NWITGGIATAMACLVGL 68 143
HLA-DQA1*01:03/DQB1*06:02 NWITGGIAIAMACLV NWITGGIATAMACLV 72 151
HLA-DRB1*07:01 LAAVYRINWITGGIAIAMA LAAVYRINWITGGIATAMA 164 342
HLA-DRB1*07:01 VYRINWITGGIAIAM VYRINWITGGIATAM 60 125
HLA-DRB1*07:01 AAVYRINWITGGIAIAMAC AAVYRINWITGGIATAMAC 185 385
HLA-DRB1*07:01 AAVYRINWITGGIAIAM AAVYRINWITGGIATAM 103 213
HLA-DQA1*01:03/DQB1*06:02 AVYRINWITGGIAIAMA AVYRINWITGGIATAMA 93 192
HLA-DRB1*07:01 AVYRINWITGGIAIAMACL AVYRINWITGGIATAMACL 200 412
HLA-DQA1*01:02/DQB1*05:01 INWITGGIAIAMACLVGL INWITGGIATAMACLVGL 117 241
HLA-DQA1*01:02/DQB1*05:03 INWITGGIAIAMACL INWITGGIATAMACL 252 514
HLA-DQA1*01:02/DQB1*06:02 AVYRINWITGGIAIAMACL AVYRINWITGGIATAMACL 129 263
HLA-DQA1*01:02/DQB1*06:02 LAAVYRINWITGGIAIAMAC LAAVYRINWITGGIATAMAC 123 250
HLA-DQA1*01:02/DQB1*05:03 NWITGGIAIAMACLVG NWITGGIATAMACLVG 239 485
HLA-DQA1*01:02/DQB1*06:03 RINWITGGIAIAMAC RINWITGGIATAMAC 482 978
HLA-DQA1*01:02/DQB1*06:02 VYRINWITGGIAIAMACLV VYRINWITGGIATAMACLV 118 239
HLA-DQA1*01:02/DQB1*06:02 YRINWITGGIAIAMACLVG YRINWITGGIATAMACLVG 123 249
HLA-DRB1*07:01 AAVYRINWITGGIAIA AAVYRINWITGGIATA 134 271
HLA-DQA1*01:02/DQB1*06:03 INWITGGIAIAMACL INWITGGIATAMACL 464 930
HLA-DRB1*07:01 AVYRINWITGGIAIA AVYRINWITGGIATA 66 132
HLA-DQA1*01:02/DQB1*05:01 ITGGIAIAMACLVGLM ITGGIATAMACLVGLM 88 176
HLA-DQA1*01:02/DQB1*06:02 NWITGGIAIAMACLVGLMW NWITGGIATAMACLVGLMW 168 336

NS3 protein

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NS3

S26L

Reference  MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFGWLIVGVA
           ||||||||||||||||||||||||| |||||||||||||||||||||||||
Mutated    MDLFMRIFTIGTVTLKQGEIKDATPLDFVRATATIPIQASLPFGWLIVGVA

Export table to csv 
Allele Reference peptide Mutated peptide Reference affinity (IC50, nM) Mutated affinity (IC50, nM)
HLA-DRB1*01:01 KDATPSDFVRATATI KDATPLDFVRATATI 1074 54
HLA-DRB1*01:02 KDATPSDFVRATATI KDATPLDFVRATATI 3111 181
HLA-DRB1*10:01 KDATPSDFVRATATI KDATPLDFVRATATI 1785 111
HLA-DRB1*07:01 KDATPSDFVRATATI KDATPLDFVRATATI 3312 218
HLA-DRB1*10:01 IKDATPSDFVRATATI IKDATPLDFVRATATI 2698 265
HLA-DRB1*10:01 EIKDATPSDFVRATATI EIKDATPLDFVRATATI 2244 226
HLA-DRB1*01:01 IKDATPSDFVRATATI IKDATPLDFVRATATI 2502 254
HLA-DRB1*01:01 EIKDATPSDFVRATATI EIKDATPLDFVRATATI 2147 229
HLA-DRB1*10:01 IKDATPSDFVRATAT IKDATPLDFVRATAT 1867 245
HLA-DRB1*10:01 QGEIKDATPSDFVRATATI QGEIKDATPLDFVRATATI 2226 312
HLA-DRB1*01:01 IKDATPSDFVRATAT IKDATPLDFVRATAT 1219 174
HLA-DRB1*07:01 IKDATPSDFVRATAT IKDATPLDFVRATAT 2457 360
HLA-DRB1*01:02 DATPSDFVRATATIP DATPLDFVRATATIP 906 135
HLA-DPA1*03:01/DPB1*01:01 KQGEIKDATPSDFVR KQGEIKDATPLDFVR 2779 456
HLA-DRB1*01:02 KDATPSDFVRATATIP KDATPLDFVRATATIP 2447 410
HLA-DRB1*01:02 IKDATPSDFVRATAT IKDATPLDFVRATAT 2810 472
HLA-DRB1*01:01 QGEIKDATPSDFVRATATI QGEIKDATPLDFVRATATI 2150 374
HLA-DRB1*10:01 KQGEIKDATPSDFVRATATI KQGEIKDATPLDFVRATATI 1174 207
HLA-DPA1*03:01/DPB1*01:01 LKQGEIKDATPSDFVR LKQGEIKDATPLDFVR 2622 480
HLA-DRB1*01:02 IKDATPSDFVRATATIP IKDATPLDFVRATATIP 2269 416
HLA-DRB1*10:01 GEIKDATPSDFVRATAT GEIKDATPLDFVRATAT 2511 470
HLA-DQA1*01:02/DQB1*05:01 KDATPSDFVRATATI KDATPLDFVRATATI 2202 429
HLA-DRB1*01:01 KQGEIKDATPSDFVRATATI KQGEIKDATPLDFVRATATI 976 196
HLA-DPA1*03:01/DPB1*01:01 QGEIKDATPSDFVRA QGEIKDATPLDFVRA 1681 343
HLA-DPA1*03:01/DPB1*01:01 KQGEIKDATPSDFVRA KQGEIKDATPLDFVRA 1709 363
HLA-DRB1*07:01 KQGEIKDATPSDFVRATATI KQGEIKDATPLDFVRATATI 1558 331
HLA-DPA1*03:01/DPB1*01:01 QGEIKDATPSDFVRAT QGEIKDATPLDFVRAT 1665 357
HLA-DPA1*03:01/DPB1*01:01 GEIKDATPSDFVRAT GEIKDATPLDFVRAT 1752 379
HLA-DPA1*03:01/DPB1*01:01 QGEIKDATPSDFVRATATI QGEIKDATPLDFVRATATI 1459 327
HLA-DPA1*03:01/DPB1*01:01 KQGEIKDATPSDFVRATAT KQGEIKDATPLDFVRATAT 1483 333
HLA-DPA1*03:01/DPB1*01:01 TLKQGEIKDATPSDFVRAT TLKQGEIKDATPLDFVRAT 1609 370
HLA-DPA1*03:01/DPB1*01:01 KQGEIKDATPSDFVRAT KQGEIKDATPLDFVRAT 1772 411
HLA-DPA1*03:01/DPB1*01:01 VTLKQGEIKDATPSDFVRA VTLKQGEIKDATPLDFVRA 1571 366
HLA-DPA1*03:01/DPB1*01:01 TVTLKQGEIKDATPSDFVR TVTLKQGEIKDATPLDFVR 2124 495
HLA-DPA1*03:01/DPB1*01:01 LKQGEIKDATPSDFVRA LKQGEIKDATPLDFVRA 1826 428
HLA-DPA1*03:01/DPB1*01:01 LKQGEIKDATPSDFVRATA LKQGEIKDATPLDFVRATA 1512 355
HLA-DPA1*03:01/DPB1*01:01 EIKDATPSDFVRATAT EIKDATPLDFVRATAT 1669 394
HLA-DPA1*03:01/DPB1*01:01 GEIKDATPSDFVRATA GEIKDATPLDFVRATA 1616 386
HLA-DPA1*03:01/DPB1*01:01 EIKDATPSDFVRATA EIKDATPLDFVRATA 1621 393
HLA-DPA1*03:01/DPB1*04:01 KQGEIKDATPSDFVRATATI KQGEIKDATPLDFVRATATI 2035 498
HLA-DPA1*03:01/DPB1*01:01 QGEIKDATPSDFVRATA QGEIKDATPLDFVRATA 1625 400
HLA-DPA1*03:01/DPB1*01:01 GEIKDATPSDFVRATAT GEIKDATPLDFVRATAT 1664 416
HLA-DQA1*01:02/DQB1*05:01 EIKDATPSDFVRATATI EIKDATPLDFVRATATI 1342 338
HLA-DQA1*01:02/DQB1*05:01 IKDATPSDFVRATATI IKDATPLDFVRATATI 1412 356
HLA-DPA1*03:01/DPB1*01:01 EIKDATPSDFVRATATI EIKDATPLDFVRATATI 1665 420
HLA-DRB1*07:01 KQGEIKDATPSDFVR KQGEIKDATPLDFVR 1867 474
HLA-DPA1*03:01/DPB1*01:01 KQGEIKDATPSDFVRATATI KQGEIKDATPLDFVRATATI 981 255
HLA-DRB1*07:01 LKQGEIKDATPSDFVRATAT LKQGEIKDATPLDFVRATAT 1580 413
HLA-DPA1*03:01/DPB1*01:01 LKQGEIKDATPSDFVRATAT LKQGEIKDATPLDFVRATAT 987 258
HLA-DRB1*01:02 QGEIKDATPSDFVRATATIP QGEIKDATPLDFVRATATIP 1665 436
HLA-DPA1*03:01/DPB1*02:01 VTLKQGEIKDATPSDFVRAT VTLKQGEIKDATPLDFVRAT 1414 371
HLA-DPA1*03:01/DPB1*02:01 TVTLKQGEIKDATPSDFVRA TVTLKQGEIKDATPLDFVRA 1523 402
HLA-DPA1*03:01/DPB1*01:01 GEIKDATPSDFVRATATIP GEIKDATPLDFVRATATIP 1279 339
HLA-DPA1*03:01/DPB1*02:01 QGEIKDATPSDFVRATATI QGEIKDATPLDFVRATATI 1730 467
HLA-DPA1*03:01/DPB1*01:01 GTVTLKQGEIKDATPSDFVR GTVTLKQGEIKDATPLDFVR 1379 373
HLA-DPA1*03:01/DPB1*01:01 VTLKQGEIKDATPSDFVRAT VTLKQGEIKDATPLDFVRAT 1003 274
HLA-DPA1*03:01/DPB1*02:01 KQGEIKDATPSDFVRATAT KQGEIKDATPLDFVRATAT 1770 487
HLA-DQA1*01:02/DQB1*05:01 QGEIKDATPSDFVRATATI QGEIKDATPLDFVRATATI 1241 342
HLA-DRB1*10:01 LKQGEIKDATPSDFVRATAT LKQGEIKDATPLDFVRATAT 1347 374
HLA-DPA1*03:01/DPB1*01:01 TVTLKQGEIKDATPSDFVRA TVTLKQGEIKDATPLDFVRA 1001 278
HLA-DQA1*01:02/DQB1*05:01 IKDATPSDFVRATAT IKDATPLDFVRATAT 1673 472
HLA-DPA1*03:01/DPB1*01:01 TLKQGEIKDATPSDFVRATA TLKQGEIKDATPLDFVRATA 978 276
HLA-DRB1*07:01 QGEIKDATPSDFVRA QGEIKDATPLDFVRA 1354 385
HLA-DQA1*01:02/DQB1*05:01 KQGEIKDATPSDFVRATATI KQGEIKDATPLDFVRATATI 757 219
HLA-DPA1*03:01/DPB1*02:01 KQGEIKDATPSDFVRATATI KQGEIKDATPLDFVRATATI 1068 312
HLA-DQA1*01:02/DQB1*05:01 DATPSDFVRATATIP DATPLDFVRATATIP 1165 341
HLA-DPA1*03:01/DPB1*01:01 QGEIKDATPSDFVRATATIP QGEIKDATPLDFVRATATIP 807 237
HLA-DPA1*02:02/DPB1*01:01 TVTLKQGEIKDATPSDFVRA TVTLKQGEIKDATPLDFVRA 1271 376
HLA-DPA1*03:01/DPB1*02:01 TLKQGEIKDATPSDFVRATA TLKQGEIKDATPLDFVRATA 1156 342
HLA-DPA1*02:02/DPB1*01:01 KQGEIKDATPSDFVRATATI KQGEIKDATPLDFVRATATI 1204 357
HLA-DPA1*02:02/DPB1*01:01 LKQGEIKDATPSDFVRATAT LKQGEIKDATPLDFVRATAT 1203 362
HLA-DPA1*03:01/DPB1*02:01 LKQGEIKDATPSDFVRATAT LKQGEIKDATPLDFVRATAT 1086 327
HLA-DPA1*03:01/DPB1*04:01 QGEIKDATPSDFVRATATIP QGEIKDATPLDFVRATATIP 1637 494
HLA-DPA1*02:02/DPB1*01:01 VTLKQGEIKDATPSDFVRAT VTLKQGEIKDATPLDFVRAT 1253 381
HLA-DQA1*01:02/DQB1*05:01 IKDATPSDFVRATATIP IKDATPLDFVRATATIP 1039 318
HLA-DQA1*01:02/DQB1*05:01 KQGEIKDATPSDFVRATAT KQGEIKDATPLDFVRATAT 1300 415
HLA-DRB1*01:01 LKQGEIKDATPSDFVRATAT LKQGEIKDATPLDFVRATAT 1165 375
HLA-DQA1*01:02/DQB1*05:01 LKQGEIKDATPSDFVRATAT LKQGEIKDATPLDFVRATAT 785 253
HLA-DPA1*02:02/DPB1*01:01 TLKQGEIKDATPSDFVRATA TLKQGEIKDATPLDFVRATA 1169 378
HLA-DQA1*01:02/DQB1*05:01 EIKDATPSDFVRATAT EIKDATPLDFVRATAT 1245 403
HLA-DQA1*01:02/DQB1*05:01 GEIKDATPSDFVRATAT GEIKDATPLDFVRATAT 1473 478
HLA-DQA1*01:02/DQB1*05:01 KDATPSDFVRATATIP KDATPLDFVRATATIP 1080 353
HLA-DRB1*13:02 QGEIKDATPSDFVRA QGEIKDATPLDFVRA 1335 438
HLA-DPA1*03:01/DPB1*02:01 QGEIKDATPSDFVRATATIP QGEIKDATPLDFVRATATIP 935 308
HLA-DQA1*01:02/DQB1*05:01 GEIKDATPSDFVRATATIP GEIKDATPLDFVRATATIP 924 306
HLA-DQA1*01:02/DQB1*05:01 QGEIKDATPSDFVRATATIP QGEIKDATPLDFVRATATIP 566 188
HLA-DPA1*02:02/DPB1*01:01 QGEIKDATPSDFVRATATIP QGEIKDATPLDFVRATATIP 1046 350
HLA-DPA1*03:01/DPB1*01:01 IGTVTLKQGEIKDATPSDFV IGTVTLKQGEIKDATPLDFV 1332 449
HLA-DRB1*01:02 KDATPSDFVRATATIPI KDATPLDFVRATATIPI 679 234
HLA-DRB1*01:02 DATPSDFVRATATIPI DATPLDFVRATATIPI 639 232
HLA-DRB1*01:02 ATPSDFVRATATIPI ATPLDFVRATATIPI 206 75
HLA-DRB1*01:02 EIKDATPSDFVRATATIPI EIKDATPLDFVRATATIPI 1029 394
HLA-DRB1*01:02 GEIKDATPSDFVRATATIPI GEIKDATPLDFVRATATIPI 723 281
HLA-DRB1*01:01 QGEIKDATPSDFVRA QGEIKDATPLDFVRA 1187 464
HLA-DRB1*01:01 GEIKDATPSDFVRATATIP GEIKDATPLDFVRATATIP 485 202
HLA-DQA1*01:02/DQB1*05:01 TLKQGEIKDATPSDFVRATA TLKQGEIKDATPLDFVRATA 787 330
HLA-DRB1*01:01 KDATPSDFVRATATIP KDATPLDFVRATATIP 284 120
HLA-DRB1*01:01 IKDATPSDFVRATATIP IKDATPLDFVRATATIP 266 113
HLA-DRB1*10:01 QGEIKDATPSDFVRATATIP QGEIKDATPLDFVRATATIP 248 107
HLA-DQA1*01:02/DQB1*05:01 GTVTLKQGEIKDATPSDFVR GTVTLKQGEIKDATPLDFVR 1039 452
HLA-DRB1*01:01 QGEIKDATPSDFVRATATIP QGEIKDATPLDFVRATATIP 244 108
HLA-DRB1*10:01 GEIKDATPSDFVRATATIP GEIKDATPLDFVRATATIP 386 174
HLA-DRB1*01:01 DATPSDFVRATATIP DATPLDFVRATATIP 64 29
HLA-DQA1*01:02/DQB1*05:01 VTLKQGEIKDATPSDFVRAT VTLKQGEIKDATPLDFVRAT 765 348
HLA-DQA1*01:02/DQB1*05:01 IKDATPSDFVRATATIPI IKDATPLDFVRATATIPI 513 236
HLA-DQA1*01:02/DQB1*05:01 TVTLKQGEIKDATPSDFVRA TVTLKQGEIKDATPLDFVRA 746 347
HLA-DPA1*03:01/DPB1*01:01 EIKDATPSDFVRATATIPI EIKDATPLDFVRATATIPI 489 230
HLA-DPA1*03:01/DPB1*01:01 GEIKDATPSDFVRATATIPI GEIKDATPLDFVRATATIPI 343 163
HLA-DRB1*10:01 IKDATPSDFVRATATIP IKDATPLDFVRATATIP 216 106
HLA-DPA1*03:01/DPB1*02:01 EIKDATPSDFVRATATIPI EIKDATPLDFVRATATIPI 695 345
HLA-DRB1*11:04 ATPSDFVRATATIPI ATPLDFVRATATIPI 930 465

NS7a protein

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NS7a

V82A

Reference  TCFSTQFAFACPDGVKHVYQLRARSVSPKLFIRQEEVQELYSPIFLIVAAI
           ||||||||||||||||||||||||| |||||||||||||||||||||||||
Mutated    TCFSTQFAFACPDGVKHVYQLRARSASPKLFIRQEEVQELYSPIFLIVAAI

Export table to csv 
Allele Reference peptide Mutated peptide Reference affinity (IC50, nM) Mutated affinity (IC50, nM)
HLA-DRB1*07:01 PDGVKHVYQLRARSV PDGVKHVYQLRARSA 56 263
HLA-DRB1*07:01 DGVKHVYQLRARSVS DGVKHVYQLRARSAS 55 252
HLA-DRB1*07:01 VKHVYQLRARSVSPK VKHVYQLRARSASPK 62 284
HLA-DRB1*07:01 GVKHVYQLRARSVSP GVKHVYQLRARSASP 68 301
HLA-DRB1*07:01 FACPDGVKHVYQLRARSVS FACPDGVKHVYQLRARSAS 227 983
HLA-DRB1*07:01 ACPDGVKHVYQLRARSVSP ACPDGVKHVYQLRARSASP 241 1027
HLA-DPA1*01:03/DPB1*02:01 RARSVSPKLFIRQEE RARSASPKLFIRQEE 409 1731
HLA-DPA1*01:03/DPB1*02:01 ARSVSPKLFIRQEEV ARSASPKLFIRQEEV 297 1241
HLA-DRB1*07:01 CPDGVKHVYQLRARSVSPK CPDGVKHVYQLRARSASPK 197 821
HLA-DRB1*07:01 ACPDGVKHVYQLRARSV ACPDGVKHVYQLRARSA 151 624
HLA-DRB1*07:01 PDGVKHVYQLRARSVS PDGVKHVYQLRARSAS 172 710
HLA-DPA1*01:03/DPB1*02:01 RARSVSPKLFIRQEEV RARSASPKLFIRQEEV 329 1353
HLA-DRB1*07:01 DGVKHVYQLRARSVSP DGVKHVYQLRARSASP 209 858
HLA-DRB1*07:01 CPDGVKHVYQLRARSV CPDGVKHVYQLRARSA 181 743
HLA-DPA1*01:03/DPB1*02:01 RARSVSPKLFIRQEEVQ RARSASPKLFIRQEEVQ 365 1479
HLA-DRB1*07:01 CPDGVKHVYQLRARSVS CPDGVKHVYQLRARSAS 140 566
HLA-DRB1*07:01 AFACPDGVKHVYQLRARSV AFACPDGVKHVYQLRARSA 270 1086
HLA-DRB1*07:01 ACPDGVKHVYQLRARSVSPK ACPDGVKHVYQLRARSASPK 113 448
HLA-DPA1*01:03/DPB1*02:01 LRARSVSPKLFIRQEE LRARSASPKLFIRQEE 447 1767
HLA-DRB1*07:01 FACPDGVKHVYQLRARSVSP FACPDGVKHVYQLRARSASP 142 557
HLA-DPA1*01:03/DPB1*02:01 ARSVSPKLFIRQEEVQE ARSASPKLFIRQEEVQE 432 1693
HLA-DPA1*01:03/DPB1*02:01 LRARSVSPKLFIRQEEV LRARSASPKLFIRQEEV 329 1286
HLA-DPA1*01:03/DPB1*02:01 ARSVSPKLFIRQEEVQ ARSASPKLFIRQEEVQ 383 1495
HLA-DPA1*01:03/DPB1*02:01 LRARSVSPKLFIRQE LRARSASPKLFIRQE 366 1401
HLA-DRB1*07:01 GVKHVYQLRARSVSPK GVKHVYQLRARSASPK 181 682
HLA-DPA1*01:03/DPB1*02:01 RSVSPKLFIRQEEVQ RSASPKLFIRQEEVQ 417 1571
HLA-DRB1*07:01 PDGVKHVYQLRARSVSP PDGVKHVYQLRARSASP 166 622
HLA-DPA1*01:03/DPB1*02:01 QLRARSVSPKLFIRQE QLRARSASPKLFIRQE 480 1754
HLA-DRB1*07:01 AFACPDGVKHVYQLRARSVS AFACPDGVKHVYQLRARSAS 147 533
HLA-DPA1*01:03/DPB1*02:01 QLRARSVSPKLFIRQEEVQ QLRARSASPKLFIRQEEVQ 377 1339
HLA-DPA1*01:03/DPB1*02:01 QLRARSVSPKLFIRQEE QLRARSASPKLFIRQEE 493 1750
HLA-DRB1*07:01 DGVKHVYQLRARSVSPK DGVKHVYQLRARSASPK 142 501
HLA-DPA1*01:03/DPB1*02:01 YQLRARSVSPKLFIRQEEV YQLRARSASPKLFIRQEEV 366 1291
HLA-DPA1*01:03/DPB1*02:01 LRARSVSPKLFIRQEEVQE LRARSASPKLFIRQEEVQE 400 1392
HLA-DRB1*07:01 PDGVKHVYQLRARSVSPKL PDGVKHVYQLRARSASPKL 188 654
HLA-DQA1*05:01/DQB1*03:01 QLRARSVSPKLFIRQ QLRARSASPKLFIRQ 1107 320
HLA-DPA1*01:03/DPB1*02:01 QLRARSVSPKLFIRQ QLRARSASPKLFIRQ 390 1339
HLA-DQA1*05:01/DQB1*03:01 LRARSVSPKLFIRQE LRARSASPKLFIRQE 1288 376
HLA-DRB1*07:01 CPDGVKHVYQLRARSVSPKL CPDGVKHVYQLRARSASPKL 104 340
HLA-DPA1*01:03/DPB1*02:01 YQLRARSVSPKLFIRQEEVQ YQLRARSASPKLFIRQEEVQ 287 912
HLA-DRB1*13:02 DGVKHVYQLRARSVS DGVKHVYQLRARSAS 207 655
HLA-DPA1*01:03/DPB1*02:01 QLRARSVSPKLFIRQEEVQE QLRARSASPKLFIRQEEVQE 301 947
HLA-DQA1*05:01/DQB1*03:01 YQLRARSVSPKLFIR YQLRARSASPKLFIR 1010 324
HLA-DPA1*01:03/DPB1*02:01 VYQLRARSVSPKLFIRQEEV VYQLRARSASPKLFIRQEEV 270 841
HLA-DRB1*07:01 FAFACPDGVKHVYQLRARSV FAFACPDGVKHVYQLRARSA 179 551
HLA-DRB1*13:02 PDGVKHVYQLRARSV PDGVKHVYQLRARSA 245 749
HLA-DRB1*07:01 VKHVYQLRARSVSPKL VKHVYQLRARSASPKL 189 577
HLA-DRB1*07:01 GVKHVYQLRARSVSPKL GVKHVYQLRARSASPKL 137 411
HLA-DRB1*13:02 GVKHVYQLRARSVSP GVKHVYQLRARSASP 236 704
HLA-DRB1*13:02 VKHVYQLRARSVSPK VKHVYQLRARSASPK 198 589
HLA-DQA1*05:01/DQB1*03:01 QLRARSVSPKLFIRQE QLRARSASPKLFIRQE 1173 396
HLA-DRB1*07:01 KHVYQLRARSVSPKL KHVYQLRARSASPKL 84 248
HLA-DQA1*05:01/DQB1*03:01 YQLRARSVSPKLFIRQ YQLRARSASPKLFIRQ 1063 368
HLA-DQA1*05:01/DQB1*03:01 LRARSVSPKLFIRQEE LRARSASPKLFIRQEE 1338 468
HLA-DRB1*07:01 DGVKHVYQLRARSVSPKLF DGVKHVYQLRARSASPKLF 173 494
HLA-DRB1*07:01 PDGVKHVYQLRARSVSPKLF PDGVKHVYQLRARSASPKLF 97 271
HLA-DPA1*03:01/DPB1*02:01 RARSVSPKLFIRQEE RARSASPKLFIRQEE 337 932
HLA-DPA1*03:01/DPB1*02:01 HVYQLRARSVSPKLFIRQE HVYQLRARSASPKLFIRQE 271 729
HLA-DQA1*05:01/DQB1*03:01 VYQLRARSVSPKLFIR VYQLRARSASPKLFIR 1014 379
HLA-DRB1*13:02 CPDGVKHVYQLRARSVSPK CPDGVKHVYQLRARSASPK 498 1331
HLA-DPA1*01:03/DPB1*02:01 HVYQLRARSVSPKLFIRQEE HVYQLRARSASPKLFIRQEE 394 1053
HLA-DPA1*03:01/DPB1*02:01 KHVYQLRARSVSPKLFIRQ KHVYQLRARSASPKLFIRQ 248 654
HLA-DQA1*05:01/DQB1*03:01 VYQLRARSVSPKLFIRQ VYQLRARSASPKLFIRQ 1298 493
HLA-DPA1*01:03/DPB1*02:01 KHVYQLRARSVSPKLFIRQE KHVYQLRARSASPKLFIRQE 380 986
HLA-DPA1*03:01/DPB1*02:01 VKHVYQLRARSVSPK VKHVYQLRARSASPK 350 906
HLA-DPA1*03:01/DPB1*02:01 HVYQLRARSVSPKLFIRQEE HVYQLRARSASPKLFIRQEE 177 457
HLA-DPA1*03:01/DPB1*02:01 VYQLRARSVSPKLFIRQ VYQLRARSASPKLFIRQ 277 715
HLA-DPA1*03:01/DPB1*02:01 LRARSVSPKLFIRQE LRARSASPKLFIRQE 278 717
HLA-DPA1*03:01/DPB1*02:01 QLRARSVSPKLFIRQ QLRARSASPKLFIRQ 256 657
HLA-DPA1*03:01/DPB1*02:01 ARSVSPKLFIRQEEV ARSASPKLFIRQEEV 182 466
HLA-DPA1*03:01/DPB1*02:01 KHVYQLRARSVSPKLFIRQE KHVYQLRARSASPKLFIRQE 158 404
HLA-DQA1*05:01/DQB1*06:01 LRARSVSPKLFIRQE LRARSASPKLFIRQE 1147 449
HLA-DQA1*05:01/DQB1*03:01 VYQLRARSVSPKLFI VYQLRARSASPKLFI 936 370
HLA-DRB1*14:04 VKHVYQLRARSVSPK VKHVYQLRARSASPK 332 838
HLA-DPA1*03:01/DPB1*02:01 VKHVYQLRARSVSPKLF VKHVYQLRARSASPKLF 392 989
HLA-DPA1*01:03/DPB1*02:01 RARSVSPKLFIRQEEVQEL RARSASPKLFIRQEEVQEL 352 875
HLA-DPA1*03:01/DPB1*02:01 QLRARSVSPKLFIRQE QLRARSASPKLFIRQE 322 798
HLA-DRB1*13:02 PDGVKHVYQLRARSVSPKL PDGVKHVYQLRARSASPKL 420 1036
HLA-DPA1*03:01/DPB1*02:01 YQLRARSVSPKLFIRQE YQLRARSASPKLFIRQE 316 778
HLA-DRB1*14:04 KHVYQLRARSVSPKL KHVYQLRARSASPKL 467 1141
HLA-DRB1*13:02 FACPDGVKHVYQLRARSVSP FACPDGVKHVYQLRARSASP 376 917
HLA-DPA1*03:01/DPB1*02:01 VKHVYQLRARSVSPKLFIRQ VKHVYQLRARSASPKLFIRQ 146 355
HLA-DPA1*03:01/DPB1*02:01 VKHVYQLRARSVSPKL VKHVYQLRARSASPKL 423 1028
HLA-DPA1*03:01/DPB1*02:01 LRARSVSPKLFIRQEE LRARSASPKLFIRQEE 346 836
HLA-DQA1*05:01/DQB1*06:01 QLRARSVSPKLFIRQ QLRARSASPKLFIRQ 936 389
HLA-DPA1*03:01/DPB1*02:01 VYQLRARSVSPKLFIRQEE VYQLRARSASPKLFIRQEE 304 731
HLA-DQA1*05:01/DQB1*03:01 HVYQLRARSVSPKLFIR HVYQLRARSASPKLFIR 1192 496
HLA-DRB1*07:01 VKHVYQLRARSVSPKLF VKHVYQLRARSASPKLF 129 309
HLA-DPA1*03:01/DPB1*02:01 RSVSPKLFIRQEEVQ RSASPKLFIRQEEVQ 226 533
HLA-DRB1*13:02 GVKHVYQLRARSVSPK GVKHVYQLRARSASPK 491 1157
HLA-DRB1*13:02 AFACPDGVKHVYQLRARSVS AFACPDGVKHVYQLRARSAS 397 934
HLA-DPA1*03:01/DPB1*02:01 QLRARSVSPKLFIRQEE QLRARSASPKLFIRQEE 347 815
HLA-DQA1*05:01/DQB1*03:01 HVYQLRARSVSPKLFI HVYQLRARSASPKLFI 986 421
HLA-DQA1*05:01/DQB1*06:01 QLRARSVSPKLFIRQE QLRARSASPKLFIRQE 1114 477
HLA-DPA1*03:01/DPB1*02:01 YQLRARSVSPKLFIRQ YQLRARSASPKLFIRQ 307 715
HLA-DRB1*07:01 DGVKHVYQLRARSVSPKLFI DGVKHVYQLRARSASPKLFI 92 213
HLA-DRB1*15:02 GVKHVYQLRARSVSP GVKHVYQLRARSASP 335 772
HLA-DPA1*03:01/DPB1*02:01 KHVYQLRARSVSPKLFI KHVYQLRARSASPKLFI 409 941
HLA-DRB1*15:02 VKHVYQLRARSVSPK VKHVYQLRARSASPK 292 667
HLA-DRB1*07:01 GVKHVYQLRARSVSPKLFI GVKHVYQLRARSASPKLFI 159 362
HLA-DPA1*01:03/DPB1*02:01 LRARSVSPKLFIRQEEVQEL LRARSASPKLFIRQEEVQEL 241 547
HLA-DPA1*03:01/DPB1*02:01 DGVKHVYQLRARSVSPKLF DGVKHVYQLRARSASPKLF 304 688
HLA-DPA1*03:01/DPB1*02:01 ARSVSPKLFIRQEEVQ ARSASPKLFIRQEEVQ 225 508
HLA-DPA1*03:01/DPB1*02:01 RARSVSPKLFIRQEEV RARSASPKLFIRQEEV 220 496
HLA-DRB1*13:02 DGVKHVYQLRARSVSPK DGVKHVYQLRARSASPK 454 1018
HLA-DPA1*01:03/DPB1*02:01 VKHVYQLRARSVSPKLFIRQ VKHVYQLRARSASPKLFIRQ 412 922
HLA-DPA1*03:01/DPB1*02:01 VYQLRARSVSPKLFIRQEEV VYQLRARSASPKLFIRQEEV 139 310
HLA-DPA1*03:01/DPB1*02:01 CPDGVKHVYQLRARSVSPK CPDGVKHVYQLRARSASPK 298 664
HLA-DPA1*03:01/DPB1*02:01 PDGVKHVYQLRARSVSPKL PDGVKHVYQLRARSASPKL 295 657
HLA-DPA1*03:01/DPB1*02:01 ACPDGVKHVYQLRARSVSP ACPDGVKHVYQLRARSASP 316 702
HLA-DRB1*15:02 DGVKHVYQLRARSVS DGVKHVYQLRARSAS 318 706
HLA-DRB1*13:02 ACPDGVKHVYQLRARSVSPK ACPDGVKHVYQLRARSASPK 297 656
HLA-DPA1*03:01/DPB1*02:01 RARSVSPKLFIRQEEVQ RARSASPKLFIRQEEVQ 226 497
HLA-DPA1*03:01/DPB1*02:01 GVKHVYQLRARSVSPKLFI GVKHVYQLRARSASPKLFI 292 642
HLA-DPA1*03:01/DPB1*02:01 ARSVSPKLFIRQEEVQE ARSASPKLFIRQEEVQE 244 534
HLA-DPA1*03:01/DPB1*02:01 LRARSVSPKLFIRQEEV LRARSASPKLFIRQEEV 215 469
HLA-DPA1*03:01/DPB1*02:01 ACPDGVKHVYQLRARSV ACPDGVKHVYQLRARSA 329 717
HLA-DRB1*15:01 PDGVKHVYQLRARSVSPKL PDGVKHVYQLRARSASPKL 142 308
HLA-DRB1*15:01 CPDGVKHVYQLRARSVSPK CPDGVKHVYQLRARSASPK 148 321
HLA-DPA1*03:01/DPB1*02:01 GVKHVYQLRARSVSPK GVKHVYQLRARSASPK 344 746
HLA-DPA1*03:01/DPB1*02:01 VKHVYQLRARSVSPKLFIR VKHVYQLRARSASPKLFIR 286 620
HLA-DQA1*05:01/DQB1*06:01 YQLRARSVSPKLFIR YQLRARSASPKLFIR 793 368
HLA-DQA1*05:01/DQB1*06:01 YQLRARSVSPKLFIRQ YQLRARSASPKLFIRQ 936 435
HLA-DPA1*01:03/DPB1*02:01 RSVSPKLFIRQEEVQEL RSASPKLFIRQEEVQEL 458 983
HLA-DPA1*03:01/DPB1*02:01 GVKHVYQLRARSVSP GVKHVYQLRARSASP 315 676
HLA-DRB1*15:01 DGVKHVYQLRARSVSPKLF DGVKHVYQLRARSASPKLF 139 298
HLA-DRB1*15:01 AFACPDGVKHVYQLRARSV AFACPDGVKHVYQLRARSA 334 716
HLA-DPA1*03:01/DPB1*02:01 CPDGVKHVYQLRARSVS CPDGVKHVYQLRARSAS 321 688
HLA-DQA1*05:01/DQB1*03:01 HVYQLRARSVSPKLF HVYQLRARSASPKLF 951 444
HLA-DQA1*05:01/DQB1*03:01 KHVYQLRARSVSPKLFIRQE KHVYQLRARSASPKLFIRQE 1019 476
HLA-DRB1*13:02 VKHVYQLRARSVSPKL VKHVYQLRARSASPKL 415 888
HLA-DPA1*03:01/DPB1*02:01 DGVKHVYQLRARSVSP DGVKHVYQLRARSASP 346 739
HLA-DQA1*05:01/DQB1*03:01 VKHVYQLRARSVSPKLFIRQ VKHVYQLRARSASPKLFIRQ 978 458
HLA-DPA1*03:01/DPB1*02:01 PDGVKHVYQLRARSV PDGVKHVYQLRARSA 276 589
HLA-DPA1*03:01/DPB1*02:01 ACPDGVKHVYQLRARSVSPK ACPDGVKHVYQLRARSASPK 208 443
HLA-DRB1*15:01 FACPDGVKHVYQLRARSVS FACPDGVKHVYQLRARSAS 208 443
HLA-DPA1*03:01/DPB1*02:01 GVKHVYQLRARSVSPKLFIR GVKHVYQLRARSASPKLFIR 172 366
HLA-DRB1*15:01 ACPDGVKHVYQLRARSVSP ACPDGVKHVYQLRARSASP 196 417
HLA-DPA1*03:01/DPB1*02:01 FACPDGVKHVYQLRARSVS FACPDGVKHVYQLRARSAS 309 657
HLA-DRB1*07:01 KHVYQLRARSVSPKLF KHVYQLRARSASPKLF 216 459
HLA-DRB1*13:02 DGVKHVYQLRARSVSPKLF DGVKHVYQLRARSASPKLF 399 847
HLA-DRB1*14:01 VKHVYQLRARSVSPK VKHVYQLRARSASPK 379 804
HLA-DPA1*03:01/DPB1*02:01 FACPDGVKHVYQLRARSVSP FACPDGVKHVYQLRARSASP 227 480
HLA-DPA1*03:01/DPB1*02:01 GVKHVYQLRARSVSPKL GVKHVYQLRARSASPKL 361 763
HLA-DPA1*03:01/DPB1*02:01 DGVKHVYQLRARSVS DGVKHVYQLRARSAS 278 587
HLA-DPA1*01:03/DPB1*02:01 ARSVSPKLFIRQEEVQELY ARSASPKLFIRQEEVQELY 344 726
HLA-DPA1*03:01/DPB1*02:01 DGVKHVYQLRARSVSPKLFI DGVKHVYQLRARSASPKLFI 185 390
HLA-DPA1*01:03/DPB1*02:01 RARSVSPKLFIRQEEVQELY RARSASPKLFIRQEEVQELY 222 468
HLA-DRB1*13:02 KHVYQLRARSVSPKL KHVYQLRARSASPKL 213 448
HLA-DRB1*15:02 PDGVKHVYQLRARSV PDGVKHVYQLRARSA 453 952
HLA-DRB1*15:02 KHVYQLRARSVSPKL KHVYQLRARSASPKL 386 811
HLA-DPA1*03:01/DPB1*02:01 PDGVKHVYQLRARSVSP PDGVKHVYQLRARSASP 345 724
HLA-DPA1*03:01/DPB1*02:01 YQLRARSVSPKLFIRQEEVQ YQLRARSASPKLFIRQEEVQ 144 302
HLA-DPA1*03:01/DPB1*02:01 YQLRARSVSPKLFIRQEEV YQLRARSASPKLFIRQEEV 218 455
HLA-DPA1*03:01/DPB1*02:01 CPDGVKHVYQLRARSVSPKL CPDGVKHVYQLRARSASPKL 205 427
HLA-DRB1*15:01 PDGVKHVYQLRARSV PDGVKHVYQLRARSA 97 202
HLA-DPA1*03:01/DPB1*02:01 CPDGVKHVYQLRARSV CPDGVKHVYQLRARSA 319 664
HLA-DRB1*15:01 KHVYQLRARSVSPKL KHVYQLRARSASPKL 89 185
HLA-DPA1*03:01/DPB1*02:01 PDGVKHVYQLRARSVS PDGVKHVYQLRARSAS 319 663
HLA-DPA1*03:01/DPB1*02:01 AFACPDGVKHVYQLRARSV AFACPDGVKHVYQLRARSA 323 671
HLA-DRB1*01:01 AFACPDGVKHVYQLRARSV AFACPDGVKHVYQLRARSA 69 143
HLA-DPA1*03:01/DPB1*02:01 HVYQLRARSVSPKLFIR HVYQLRARSASPKLFIR 424 877
HLA-DPA1*03:01/DPB1*02:01 PDGVKHVYQLRARSVSPKLF PDGVKHVYQLRARSASPKLF 205 424
HLA-DPA1*03:01/DPB1*02:01 DGVKHVYQLRARSVSPK DGVKHVYQLRARSASPK 340 703
HLA-DRB1*15:02 ACPDGVKHVYQLRARSVSPK ACPDGVKHVYQLRARSASPK 347 716
HLA-DPA1*03:01/DPB1*02:01 RSVSPKLFIRQEEVQE RSASPKLFIRQEEVQE 285 586
HLA-DRB1*07:01 GVKHVYQLRARSVSPKLFIR GVKHVYQLRARSASPKLFIR 91 187
HLA-DQA1*05:01/DQB1*03:01 GVKHVYQLRARSVSPKLFIR GVKHVYQLRARSASPKLFIR 982 478
HLA-DRB1*14:04 GVKHVYQLRARSVSP GVKHVYQLRARSASP 326 668
HLA-DPA1*03:01/DPB1*02:01 QLRARSVSPKLFIRQEEVQE QLRARSASPKLFIRQEEVQE 143 291
HLA-DQA1*05:01/DQB1*03:01 KHVYQLRARSVSPKLF KHVYQLRARSASPKLF 991 487
HLA-DPA1*03:01/DPB1*02:01 QLRARSVSPKLFIRQEEV QLRARSASPKLFIRQEEV 425 864
HLA-DPA1*03:01/DPB1*01:01 KHVYQLRARSVSPKLF KHVYQLRARSASPKLF 385 781
HLA-DRB1*15:01 PDGVKHVYQLRARSVS PDGVKHVYQLRARSAS 167 338
HLA-DRB1*01:01 CPDGVKHVYQLRARSV CPDGVKHVYQLRARSA 42 85
HLA-DRB1*14:04 DGVKHVYQLRARSVS DGVKHVYQLRARSAS 309 625
HLA-DRB1*01:01 FACPDGVKHVYQLRARSV FACPDGVKHVYQLRARSA 228 461
HLA-DQA1*05:01/DQB1*06:01 VYQLRARSVSPKLFIR VYQLRARSASPKLFIR 844 419
HLA-DRB1*13:02 CPDGVKHVYQLRARSVSPKL CPDGVKHVYQLRARSASPKL 238 478
HLA-DPA1*03:01/DPB1*02:01 AFACPDGVKHVYQLRARSVS AFACPDGVKHVYQLRARSAS 232 465
HLA-DRB1*01:01 FACPDGVKHVYQLRARSVS FACPDGVKHVYQLRARSAS 30 60
HLA-DRB1*15:01 VKHVYQLRARSVSPK VKHVYQLRARSASPK 62 124

T120I

Reference  ELYSPIFLIVAAIVFITLCFTLKRKTE
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Mutated    ELYSPIFLIVAAIVFITLCFTLKRKIE

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Allele Reference peptide Mutated peptide Reference affinity (IC50, nM) Mutated affinity (IC50, nM)
HLA-DRB1*07:01 IVFITLCFTLKRKTE IVFITLCFTLKRKIE 321 132
HLA-DRB1*07:01 AIVFITLCFTLKRKTE AIVFITLCFTLKRKIE 628 271
HLA-DRB1*07:01 AAIVFITLCFTLKRKTE AAIVFITLCFTLKRKIE 574 262
HLA-DRB1*07:01 LIVAAIVFITLCFTLKRKTE LIVAAIVFITLCFTLKRKIE 796 374
HLA-DRB1*07:01 AIVFITLCFTLKRKT AIVFITLCFTLKRKI 280 134
HLA-DRB1*14:01 IVFITLCFTLKRKTE IVFITLCFTLKRKIE 271 132
HLA-DRB1*07:01 IVAAIVFITLCFTLKRKTE IVAAIVFITLCFTLKRKIE 1018 496
HLA-DRB1*07:01 AAIVFITLCFTLKRKT AAIVFITLCFTLKRKI 588 287

NS9b protein

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NS9b

T60A

Reference  NNVGPKVYPIILRLGSPLSLNMARKTLNSLEDKAFQLTPIAVQMTKLATTE
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Mutated    NNVGPKVYPIILRLGSPLSLNMARKALNSLEDKAFQLTPIAVQMTKLATTE

Export table to csv 
Allele Reference peptide Mutated peptide Reference affinity (IC50, nM) Mutated affinity (IC50, nM)
HLA-DPA1*01:03/DPB1*03:01 LSLNMARKTLNSLEDKA LSLNMARKALNSLEDKA 1639 474
HLA-DRB1*11:01 SLNMARKTLNSLEDKAFQL SLNMARKALNSLEDKAFQL 977 321
HLA-DRB1*11:01 RLGSPLSLNMARKTLNSL RLGSPLSLNMARKALNSL 492 165
HLA-DRB1*11:01 SLNMARKTLNSLEDKA SLNMARKALNSLEDKA 520 175
HLA-DRB1*11:01 GSPLSLNMARKTLNSLED GSPLSLNMARKALNSLED 507 172
HLA-DRB1*11:01 LGSPLSLNMARKTLNSLE LGSPLSLNMARKALNSLE 501 170
HLA-DPA1*01:03/DPB1*03:01 LSLNMARKTLNSLEDKAFQL LSLNMARKALNSLEDKAFQL 862 297
HLA-DRB1*11:01 SLNMARKTLNSLEDKAF SLNMARKALNSLEDKAF 407 141
HLA-DRB1*11:01 LSLNMARKTLNSLEDKAFQ LSLNMARKALNSLEDKAFQ 348 121
HLA-DRB1*11:01 LRLGSPLSLNMARKTLNS LRLGSPLSLNMARKALNS 825 287
HLA-DRB1*11:01 PLSLNMARKTLNSLEDKAF PLSLNMARKALNSLEDKAF 212 74
HLA-DRB1*11:01 SPLSLNMARKTLNSLEDK SPLSLNMARKALNSLEDK 552 193
HLA-DQA1*01:02/DQB1*06:02 SPLSLNMARKTLNSLED SPLSLNMARKALNSLED 998 349
HLA-DRB1*11:01 PLSLNMARKTLNSLEDKA PLSLNMARKALNSLEDKA 667 234
HLA-DRB1*11:01 SLNMARKTLNSLEDKAFQLT SLNMARKALNSLEDKAFQLT 621 218
HLA-DPA1*01:03/DPB1*03:01 SLNMARKTLNSLEDKAFQLT SLNMARKALNSLEDKAFQLT 997 356
HLA-DRB1*11:01 LSLNMARKTLNSLEDKAF LSLNMARKALNSLEDKAF 933 334
HLA-DRB1*11:04 LSLNMARKTLNSLEDKAF LSLNMARKALNSLEDKAF 700 251
HLA-DQA1*01:02/DQB1*05:03 GSPLSLNMARKTLNS GSPLSLNMARKALNS 1143 410
HLA-DRB1*11:01 SPLSLNMARKTLNSLEDKA SPLSLNMARKALNSLEDKA 175 63
HLA-DRB1*11:04 GSPLSLNMARKTLNSLED GSPLSLNMARKALNSLED 368 133
HLA-DRB1*11:01 LGSPLSLNMARKTLNSLED LGSPLSLNMARKALNSLED 152 55
HLA-DQA1*01:02/DQB1*06:02 PLSLNMARKTLNSLEDK PLSLNMARKALNSLEDK 1138 412
HLA-DRB1*11:01 GSPLSLNMARKTLNSLEDK GSPLSLNMARKALNSLEDK 157 57
HLA-DQA1*01:02/DQB1*06:02 SPLSLNMARKTLNSLE SPLSLNMARKALNSLE 865 316
HLA-DRB1*08:04 SPLSLNMARKTLNSLEDK SPLSLNMARKALNSLEDK 799 292
HLA-DRB1*08:04 PLSLNMARKTLNSLEDKA PLSLNMARKALNSLEDKA 922 337
HLA-DRB1*08:04 SLNMARKTLNSLEDKAF SLNMARKALNSLEDKAF 618 226
HLA-DRB1*11:04 RLGSPLSLNMARKTLNSL RLGSPLSLNMARKALNSL 339 124
HLA-DRB1*11:01 RLGSPLSLNMARKTLNSLE RLGSPLSLNMARKALNSLE 153 56
HLA-DRB1*11:04 PLSLNMARKTLNSLEDKA PLSLNMARKALNSLEDKA 480 176
HLA-DRB1*11:01 LRLGSPLSLNMARKTLNSL LRLGSPLSLNMARKALNSL 163 60
HLA-DRB1*11:04 LGSPLSLNMARKTLNSLE LGSPLSLNMARKALNSLE 353 130
HLA-DRB1*08:04 LSLNMARKTLNSLEDKAF LSLNMARKALNSLEDKAF 1238 456
HLA-DPA1*01:03/DPB1*03:01 PLSLNMARKTLNSLEDKAFQ PLSLNMARKALNSLEDKAFQ 714 263
HLA-DRB1*08:04 GSPLSLNMARKTLNSLED GSPLSLNMARKALNSLED 738 272
HLA-DRB1*04:04 GSPLSLNMARKTLNSLE GSPLSLNMARKALNSLE 586 216
HLA-DRB1*08:04 RLGSPLSLNMARKTLNSL RLGSPLSLNMARKALNSL 679 251
HLA-DRB1*10:01 SLNMARKTLNSLEDKA SLNMARKALNSLEDKA 551 204
HLA-DQA1*01:02/DQB1*05:01 GSPLSLNMARKTLNSLED GSPLSLNMARKALNSLED 532 197
HLA-DQA1*01:02/DQB1*06:02 PLSLNMARKTLNSLED PLSLNMARKALNSLED 919 341
HLA-DPA1*04:01/DPB1*14:01 LSLNMARKTLNSLED LSLNMARKALNSLED 1050 390
HLA-DQA1*01:02/DQB1*05:01 PLSLNMARKTLNSLEDKA PLSLNMARKALNSLEDKA 640 238
HLA-DRB1*11:01 LSLNMARKTLNSLEDKAFQL LSLNMARKALNSLEDKAFQL 231 86
HLA-DRB1*10:01 SLNMARKTLNSLEDKAF SLNMARKALNSLEDKAF 464 173
HLA-DPA1*04:01/DPB1*14:01 PLSLNMARKTLNSLED PLSLNMARKALNSLED 893 333
HLA-DQA1*01:02/DQB1*06:02 GSPLSLNMARKTLNSLE GSPLSLNMARKALNSLE 926 346
HLA-DQA1*01:02/DQB1*05:03 PLSLNMARKTLNSLE PLSLNMARKALNSLE 1064 398
HLA-DRB1*08:04 SLNMARKTLNSLEDKA SLNMARKALNSLEDKA 671 251
HLA-DRB1*11:04 SPLSLNMARKTLNSLEDK SPLSLNMARKALNSLEDK 399 150
HLA-DQA1*01:02/DQB1*05:03 SPLSLNMARKTLNSL SPLSLNMARKALNSL 928 349
HLA-DPA1*04:01/DPB1*14:01 LSLNMARKTLNSLEDK LSLNMARKALNSLEDK 801 302
HLA-DQA1*01:02/DQB1*06:02 SPLSLNMARKTLNSL SPLSLNMARKALNSL 977 370
HLA-DRB1*08:04 LGSPLSLNMARKTLNSLE LGSPLSLNMARKALNSLE 702 266
HLA-DRB1*11:04 SLNMARKTLNSLEDKA SLNMARKALNSLEDKA 361 137
HLA-DRB1*11:01 LSLNMARKTLNSLEDKA LSLNMARKALNSLEDKA 142 54
HLA-DQA1*01:02/DQB1*05:03 PLSLNMARKTLNSLEDK PLSLNMARKALNSLEDK 959 365
HLA-DRB1*11:01 SLNMARKTLNSLEDK SLNMARKALNSLEDK 168 64
HLA-DRB1*08:02 RLGSPLSLNMARKTLNSL RLGSPLSLNMARKALNSL 735 280
HLA-DQA1*01:02/DQB1*05:01 SPLSLNMARKTLNSLEDK SPLSLNMARKALNSLEDK 534 204
HLA-DRB1*11:01 PLSLNMARKTLNSLEDK PLSLNMARKALNSLEDK 102 39
HLA-DQA1*01:02/DQB1*06:02 PLSLNMARKTLNSLE PLSLNMARKALNSLE 991 379
HLA-DRB1*08:04 LSLNMARKTLNSLEDKA LSLNMARKALNSLEDKA 264 101
HLA-DRB1*11:04 LSLNMARKTLNSLEDKAFQ LSLNMARKALNSLEDKAFQ 271 104
HLA-DRB1*04:04 SPLSLNMARKTLNSLED SPLSLNMARKALNSLED 653 251
HLA-DRB1*08:04 LSLNMARKTLNSLEDKAFQ LSLNMARKALNSLEDKAFQ 551 212
HLA-DQA1*01:02/DQB1*05:03 GSPLSLNMARKTLNSLE GSPLSLNMARKALNSLE 811 313
HLA-DQA1*01:02/DQB1*05:03 GSPLSLNMARKTLNSL GSPLSLNMARKALNSL 671 259
HLA-DQA1*01:02/DQB1*06:02 GSPLSLNMARKTLNSL GSPLSLNMARKALNSL 860 332
HLA-DQA1*01:02/DQB1*05:03 LSLNMARKTLNSLEDK LSLNMARKALNSLEDK 1042 403
HLA-DQA1*01:02/DQB1*05:03 SPLSLNMARKTLNSLED SPLSLNMARKALNSLED 817 316
HLA-DPA1*01:03/DPB1*03:01 SPLSLNMARKTLNSLEDKAF SPLSLNMARKALNSLEDKAF 641 248
HLA-DRB1*11:01 LSLNMARKTLNSLEDK LSLNMARKALNSLEDK 168 65
HLA-DRB1*11:04 LRLGSPLSLNMARKTLNS LRLGSPLSLNMARKALNS 527 204
HLA-DRB1*04:04 PLSLNMARKTLNSLEDK PLSLNMARKALNSLEDK 772 299
HLA-DRB1*11:04 PLSLNMARKTLNSLEDKAFQ PLSLNMARKALNSLEDKAFQ 111 43
HLA-DRB1*08:04 LRLGSPLSLNMARKTLNS LRLGSPLSLNMARKALNS 993 385
HLA-DPA1*04:01/DPB1*14:01 LSLNMARKTLNSLEDKA LSLNMARKALNSLEDKA 814 316
HLA-DPA1*04:01/DPB1*14:01 SPLSLNMARKTLNSLED SPLSLNMARKALNSLED 865 336
HLA-DPA1*04:01/DPB1*14:01 SLNMARKTLNSLEDK SLNMARKALNSLEDK 1157 450
HLA-DQA1*01:02/DQB1*06:02 SPLSLNMARKTLNSLEDKA SPLSLNMARKALNSLEDKA 1238 482
HLA-DRB1*11:01 RLGSPLSLNMARKTLNS RLGSPLSLNMARKALNS 136 53
HLA-DRB1*08:02 GSPLSLNMARKTLNSLED GSPLSLNMARKALNSLED 777 303
HLA-DQA1*01:02/DQB1*05:03 GSPLSLNMARKTLNSLEDKA GSPLSLNMARKALNSLEDKA 623 243
HLA-DRB1*04:04 LGSPLSLNMARKTLNSL LGSPLSLNMARKALNSL 497 194
HLA-DPA1*04:01/DPB1*14:01 GSPLSLNMARKTLNSLEDKA GSPLSLNMARKALNSLEDKA 445 174
HLA-DPA1*01:03/DPB1*03:01 GSPLSLNMARKTLNSLEDKA GSPLSLNMARKALNSLEDKA 761 298
HLA-DRB1*10:01 LSLNMARKTLNSLEDKA LSLNMARKALNSLEDKA 263 103
HLA-DRB1*08:02 LGSPLSLNMARKTLNSLE LGSPLSLNMARKALNSLE 758 297
HLA-DQA1*01:02/DQB1*05:03 PLSLNMARKTLNSLED PLSLNMARKALNSLED 778 305
HLA-DPA1*04:01/DPB1*14:01 PLSLNMARKTLNSLEDKAFQ PLSLNMARKALNSLEDKAFQ 441 173
HLA-DRB1*08:02 SLNMARKTLNSLEDKAF SLNMARKALNSLEDKAF 726 285
HLA-DRB1*10:01 LSLNMARKTLNSLEDKAF LSLNMARKALNSLEDKAF 1034 406
HLA-DPA1*04:01/DPB1*14:01 PLSLNMARKTLNSLEDKAF PLSLNMARKALNSLEDKAF 881 346
HLA-DQA1*01:02/DQB1*05:03 LGSPLSLNMARKTLNSLE LGSPLSLNMARKALNSLE 1265 497
HLA-DPA1*01:03/DPB1*06:01 LSLNMARKTLNSLEDKAFQL LSLNMARKALNSLEDKAFQL 1061 417
HLA-DRB1*11:01 PLSLNMARKTLNSLEDKAFQ PLSLNMARKALNSLEDKAFQ 127 50
HLA-DRB1*08:04 PLSLNMARKTLNSLEDKAFQ PLSLNMARKALNSLEDKAFQ 203 80
HLA-DPA1*04:01/DPB1*14:01 LGSPLSLNMARKTLNSLEDK LGSPLSLNMARKALNSLEDK 482 190
HLA-DQA1*01:02/DQB1*06:02 GSPLSLNMARKTLNS GSPLSLNMARKALNS 1145 452
HLA-DQA1*01:02/DQB1*06:02 LSLNMARKTLNSLEDK LSLNMARKALNSLEDK 1122 443
HLA-DQA1*01:02/DQB1*05:01 LGSPLSLNMARKTLNSLE LGSPLSLNMARKALNSLE 466 184
HLA-DRB1*10:01 SLNMARKTLNSLEDKAFQL SLNMARKALNSLEDKAFQL 676 267
HLA-DRB1*11:01 LGSPLSLNMARKTLNS LGSPLSLNMARKALNS 167 66
HLA-DRB1*11:01 ILRLGSPLSLNMARKTLNS ILRLGSPLSLNMARKALNS 258 102
HLA-DPA1*04:01/DPB1*14:01 LSLNMARKTLNSLEDKAFQ LSLNMARKALNSLEDKAFQ 966 382
HLA-DQA1*01:02/DQB1*05:03 SPLSLNMARKTLNSLE SPLSLNMARKALNSLE 675 267
HLA-DRB1*11:04 PLSLNMARKTLNSLEDKAF PLSLNMARKALNSLEDKAF 164 65
HLA-DQA1*01:02/DQB1*06:02 SPLSLNMARKTLNSLEDKAF SPLSLNMARKALNSLEDKAF 941 373
HLA-DRB1*08:04 SPLSLNMARKTLNSLEDKAF SPLSLNMARKALNSLEDKAF 169 67
HLA-DRB1*10:01 LSLNMARKTLNSLEDKAFQ LSLNMARKALNSLEDKAFQ 401 159
HLA-DRB1*10:01 GSPLSLNMARKTLNSLED GSPLSLNMARKALNSLED 688 273
HLA-DRB1*11:01 PLSLNMARKTLNSLED PLSLNMARKALNSLED 126 50
HLA-DQA1*01:03/DQB1*06:02 GSPLSLNMARKTLNS GSPLSLNMARKALNS 650 258
HLA-DRB1*11:04 SLNMARKTLNSLEDKAFQL SLNMARKALNSLEDKAFQL 695 276
HLA-DRB1*10:01 LNMARKTLNSLEDKAFQ LNMARKALNSLEDKAFQ 841 334
HLA-DRB1*08:02 PLSLNMARKTLNSLEDKA PLSLNMARKALNSLEDKA 966 384
HLA-DRB1*11:01 GSPLSLNMARKTLNSLE GSPLSLNMARKALNSLE 83 33
HLA-DRB1*08:04 SLNMARKTLNSLEDK SLNMARKALNSLEDK 249 99
HLA-DRB1*04:04 LSLNMARKTLNSLEDKA LSLNMARKALNSLEDKA 855 340
HLA-DPA1*04:01/DPB1*14:01 GSPLSLNMARKTLNSLEDK GSPLSLNMARKALNSLEDK 958 381
HLA-DRB1*11:04 LSLNMARKTLNSLEDKAFQL LSLNMARKALNSLEDKAFQL 191 76
HLA-DRB1*10:01 SLNMARKTLNSLEDK SLNMARKALNSLEDK 304 121
HLA-DRB1*04:02 GSPLSLNMARKTLNSLE GSPLSLNMARKALNSLE 1238 493
HLA-DQA1*01:02/DQB1*05:03 LGSPLSLNMARKTLNS LGSPLSLNMARKALNS 723 288
HLA-DQA1*01:02/DQB1*06:02 GSPLSLNMARKTLNSLEDKA GSPLSLNMARKALNSLEDKA 851 339
HLA-DRB1*10:01 LNMARKTLNSLEDKAF LNMARKALNSLEDKAF 974 388
HLA-DPA1*01:03/DPB1*03:01 LNMARKTLNSLEDKAFQLTP LNMARKALNSLEDKAFQLTP 1063 424
HLA-DRB1*04:04 GSPLSLNMARKTLNS GSPLSLNMARKALNS 376 150
HLA-DPA1*04:01/DPB1*14:01 PLSLNMARKTLNSLEDK PLSLNMARKALNSLEDK 809 323
HLA-DPA1*04:01/DPB1*14:01 SPLSLNMARKTLNSLEDKA SPLSLNMARKALNSLEDKA 884 353
HLA-DRB1*11:04 SLNMARKTLNSLEDKAF SLNMARKALNSLEDKAF 303 121
HLA-DPA1*04:01/DPB1*14:01 SPLSLNMARKTLNSLE SPLSLNMARKALNSLE 974 389
HLA-DRB1*08:04 PLSLNMARKTLNSLEDKAF PLSLNMARKALNSLEDKAF 348 139
HLA-DRB1*10:01 SPLSLNMARKTLNSLEDK SPLSLNMARKALNSLEDK 738 295
HLA-DRB1*11:01 LGSPLSLNMARKTLNSL LGSPLSLNMARKALNSL 80 32
HLA-DRB1*08:04 LGSPLSLNMARKTLNSL LGSPLSLNMARKALNSL 150 60
HLA-DRB1*08:02 GSPLSLNMARKTLNSLEDK GSPLSLNMARKALNSLEDK 315 126
HLA-DPA1*04:01/DPB1*14:01 SPLSLNMARKTLNSLEDKAF SPLSLNMARKALNSLEDKAF 405 162
HLA-DRB1*10:01 PLSLNMARKTLNSLEDKA PLSLNMARKALNSLEDKA 877 351
HLA-DPA1*01:03/DPB1*06:01 PLSLNMARKTLNSLEDKAFQ PLSLNMARKALNSLEDKAFQ 919 368
HLA-DRB1*08:04 LSLNMARKTLNSLEDK LSLNMARKALNSLEDK 287 115
HLA-DRB1*04:02 GSPLSLNMARKTLNS GSPLSLNMARKALNS 711 285
HLA-DQA1*01:02/DQB1*06:02 LSLNMARKTLNSLED LSLNMARKALNSLED 1147 460
HLA-DRB1*08:02 SPLSLNMARKTLNSLEDK SPLSLNMARKALNSLEDK 822 330
HLA-DRB1*04:02 SPLSLNMARKTLNSL SPLSLNMARKALNSL 635 255
HLA-DRB1*11:04 SLNMARKTLNSLEDK SLNMARKALNSLEDK 117 47
HLA-DRB1*11:01 SPLSLNMARKTLNSLED SPLSLNMARKALNSLED 87 35
HLA-DRB1*08:02 RLGSPLSLNMARKTLNSLE RLGSPLSLNMARKALNSLE 303 122
HLA-DRB1*08:02 LGSPLSLNMARKTLNSLED LGSPLSLNMARKALNSLED 303 122
HLA-DRB1*08:04 RLGSPLSLNMARKTLNS RLGSPLSLNMARKALNS 216 87
HLA-DRB1*08:02 SPLSLNMARKTLNSLEDKA SPLSLNMARKALNSLEDKA 345 139
HLA-DRB1*08:02 LSLNMARKTLNSLEDKAFQ LSLNMARKALNSLEDKAFQ 598 241
HLA-DQA1*01:03/DQB1*05:03 GSPLSLNMARKTLNSL GSPLSLNMARKALNSL 928 374
HLA-DPA1*04:01/DPB1*14:01 LSLNMARKTLNSLEDKAFQL LSLNMARKALNSLEDKAFQL 496 200
HLA-DPA1*01:03/DPB1*03:01 LGSPLSLNMARKTLNSLEDK LGSPLSLNMARKALNSLEDK 865 349
HLA-DQA1*01:02/DQB1*06:02 GSPLSLNMARKTLNSLEDK GSPLSLNMARKALNSLEDK 1090 440
HLA-DRB1*04:04 GSPLSLNMARKTLNSL GSPLSLNMARKALNSL 597 241
HLA-DRB1*08:04 GSPLSLNMARKTLNSLE GSPLSLNMARKALNSLE 161 65
HLA-DRB1*08:04 GSPLSLNMARKTLNSLEDK GSPLSLNMARKALNSLEDK 265 107
HLA-DRB1*11:04 SPLSLNMARKTLNSLEDKAF SPLSLNMARKALNSLEDKAF 89 36
HLA-DRB1*08:04 SPLSLNMARKTLNSLEDKA SPLSLNMARKALNSLEDKA 294 119
HLA-DQA1*01:02/DQB1*05:03 LGSPLSLNMARKTLNSLEDK LGSPLSLNMARKALNSLEDK 575 233
HLA-DRB1*08:04 LGSPLSLNMARKTLNS LGSPLSLNMARKALNS 249 101
HLA-DQA1*01:02/DQB1*05:01 RLGSPLSLNMARKTLNSL RLGSPLSLNMARKALNSL 419 170
HLA-DPA1*04:01/DPB1*14:01 GSPLSLNMARKTLNSL GSPLSLNMARKALNSL 960 390
HLA-DPA1*04:01/DPB1*14:01 SPLSLNMARKTLNSL SPLSLNMARKALNSL 989 402
HLA-DRB1*11:01 GSPLSLNMARKTLNSLEDKA GSPLSLNMARKALNSLEDKA 91 37
HLA-DRB1*04:02 LGSPLSLNMARKTLNSL LGSPLSLNMARKALNSL 1146 466
HLA-DRB1*08:04 GSPLSLNMARKTLNSLEDKA GSPLSLNMARKALNSLEDKA 150 61
HLA-DRB1*08:02 LSLNMARKTLNSLEDKA LSLNMARKALNSLEDKA 334 136
HLA-DRB1*11:04 LSLNMARKTLNSLEDK LSLNMARKALNSLEDK 130 53
HLA-DRB1*08:02 LRLGSPLSLNMARKTLNSL LRLGSPLSLNMARKALNSL 309 126
HLA-DRB1*10:01 LNMARKTLNSLEDKA LNMARKALNSLEDKA 556 227
HLA-DRB1*08:02 PLSLNMARKTLNSLEDKAF PLSLNMARKALNSLEDKAF 399 163
HLA-DQA1*01:03/DQB1*05:03 PLSLNMARKTLNSLE PLSLNMARKALNSLE 1126 460
HLA-DQA1*01:03/DQB1*05:03 SPLSLNMARKTLNSL SPLSLNMARKALNSL 996 407
HLA-DQA1*01:02/DQB1*05:03 GSPLSLNMARKTLNSLEDK GSPLSLNMARKALNSLEDK 795 325
HLA-DRB1*08:04 LSLNMARKTLNSLEDKAFQL LSLNMARKALNSLEDKAFQL 335 137
HLA-DRB1*11:01 SPLSLNMARKTLNSLE SPLSLNMARKALNSLE 110 45
HLA-DRB1*10:01 LSLNMARKTLNSLEDK LSLNMARKALNSLEDK 293 120
HLA-DRB1*08:02 LRLGSPLSLNMARKTLNS LRLGSPLSLNMARKALNS 1013 415
HLA-DRB1*11:04 GSPLSLNMARKTLNSLEDK GSPLSLNMARKALNSLEDK 122 50
HLA-DQA1*01:03/DQB1*06:02 SPLSLNMARKTLNSLE SPLSLNMARKALNSLE 583 239
HLA-DRB1*11:01 GSPLSLNMARKTLNSL GSPLSLNMARKALNSL 100 41
HLA-DRB1*08:04 RLGSPLSLNMARKTLNSLED RLGSPLSLNMARKALNSLED 139 57
HLA-DRB1*11:04 GSPLSLNMARKTLNSLEDKA GSPLSLNMARKALNSLEDKA 78 32
HLA-DQA1*01:02/DQB1*05:03 LGSPLSLNMARKTLNSLED LGSPLSLNMARKALNSLED 775 318
HLA-DPA1*04:01/DPB1*14:01 LGSPLSLNMARKTLNSLED LGSPLSLNMARKALNSLED 1045 429
HLA-DQA1*01:03/DQB1*06:02 SPLSLNMARKTLNSLEDKA SPLSLNMARKALNSLEDKA 806 331
HLA-DQA1*01:03/DQB1*06:02 GSPLSLNMARKTLNSLEDK GSPLSLNMARKALNSLEDK 749 308
HLA-DRB1*10:01 LGSPLSLNMARKTLNSLE LGSPLSLNMARKALNSLE 620 255
HLA-DRB1*08:04 LGSPLSLNMARKTLNSLEDK LGSPLSLNMARKALNSLEDK 141 58
HLA-DRB1*11:01 LGSPLSLNMARKTLNSLEDK LGSPLSLNMARKALNSLEDK 85 35
HLA-DRB1*11:01 SPLSLNMARKTLNSLEDKAF SPLSLNMARKALNSLEDKAF 102 42
HLA-DRB1*08:04 SPLSLNMARKTLNSLED SPLSLNMARKALNSLED 170 70
HLA-DQA1*01:02/DQB1*05:03 RLGSPLSLNMARKTLNSL RLGSPLSLNMARKALNSL 1180 486
HLA-DRB1*08:04 LGSPLSLNMARKTLNSLED LGSPLSLNMARKALNSLED 250 103
HLA-DPA1*04:01/DPB1*14:01 SLNMARKTLNSLEDKAF SLNMARKALNSLEDKAF 941 388
HLA-DRB1*08:02 LGSPLSLNMARKTLNS LGSPLSLNMARKALNS 320 132
HLA-DPA1*04:01/DPB1*14:01 PLSLNMARKTLNSLE PLSLNMARKALNSLE 1083 447
HLA-DQA1*01:03/DQB1*06:02 LGSPLSLNMARKTLNSLED LGSPLSLNMARKALNSLED 690 285
HLA-DRB1*08:04 PLSLNMARKTLNSLEDK PLSLNMARKALNSLEDK 196 81
HLA-DQA1*01:02/DQB1*05:03 LGSPLSLNMARKTLNSL LGSPLSLNMARKALNSL 735 304
HLA-DRB1*11:04 LGSPLSLNMARKTLNSLED LGSPLSLNMARKALNSLED 116 48
HLA-DRB1*11:04 LSLNMARKTLNSLEDKA LSLNMARKALNSLEDKA 116 48
HLA-DQA1*01:03/DQB1*05:03 SPLSLNMARKTLNSLE SPLSLNMARKALNSLE 940 389
HLA-DRB1*08:02 SLNMARKTLNSLEDKA SLNMARKALNSLEDKA 773 320
HLA-DQA1*01:03/DQB1*06:02 PLSLNMARKTLNSLED PLSLNMARKALNSLED 686 284
HLA-DQA1*01:03/DQB1*06:02 SPLSLNMARKTLNSLED SPLSLNMARKALNSLED 693 287
HLA-DPA1*04:01/DPB1*14:01 SLNMARKTLNSLEDKA SLNMARKALNSLEDKA 927 384
HLA-DRB1*01:01 SLNMARKTLNSLEDKA SLNMARKALNSLEDKA 927 384
HLA-DQA1*01:03/DQB1*05:03 GSPLSLNMARKTLNSLEDKA GSPLSLNMARKALNSLEDKA 830 344
HLA-DRB1*11:04 LRLGSPLSLNMARKTLNSL LRLGSPLSLNMARKALNSL 123 51
HLA-DQA1*01:02/DQB1*06:02 LGSPLSLNMARKTLNSLEDK LGSPLSLNMARKALNSLEDK 750 311
HLA-DRB1*11:04 SPLSLNMARKTLNSLEDKA SPLSLNMARKALNSLEDKA 135 56
HLA-DQA1*01:02/DQB1*06:02 PLSLNMARKTLNSLEDKAFQ PLSLNMARKALNSLEDKAFQ 1078 448
HLA-DRB1*11:01 RLGSPLSLNMARKTLN RLGSPLSLNMARKALN 344 143
HLA-DRB1*08:04 LRLGSPLSLNMARKTLNSL LRLGSPLSLNMARKALNSL 257 107
HLA-DRB1*01:01 SLNMARKTLNSLEDKAF SLNMARKALNSLEDKAF 742 309
HLA-DRB1*11:04 LRLGSPLSLNMARKTLNSLE LRLGSPLSLNMARKALNSLE 72 30
HLA-DRB1*11:04 LGSPLSLNMARKTLNSLEDK LGSPLSLNMARKALNSLEDK 72 30
HLA-DRB1*11:04 SLNMARKTLNSLEDKAFQLT SLNMARKALNSLEDKAFQLT 458 191
HLA-DRB1*08:04 LRLGSPLSLNMARKTLNSLE LRLGSPLSLNMARKALNSLE 139 58
HLA-DRB1*10:01 PLSLNMARKTLNSLEDKAF PLSLNMARKALNSLEDKAF 304 127
HLA-DQA1*01:03/DQB1*06:02 LGSPLSLNMARKTLN LGSPLSLNMARKALN 701 293
HLA-DRB1*11:04 LGSPLSLNMARKTLNS LGSPLSLNMARKALNS 122 51
HLA-DQA1*01:02/DQB1*05:03 LSLNMARKTLNSLEDKA LSLNMARKALNSLEDKA 1196 500
HLA-DRB1*08:04 ILRLGSPLSLNMARKTLNSL ILRLGSPLSLNMARKALNSL 153 64
HLA-DQA1*01:03/DQB1*06:02 GSPLSLNMARKTLNSL GSPLSLNMARKALNSL 534 224
HLA-DQA1*01:02/DQB1*05:03 SPLSLNMARKTLNSLEDKA SPLSLNMARKALNSLEDKA 808 339
HLA-DRB1*11:01 LGSPLSLNMARKTLN LGSPLSLNMARKALN 143 60
HLA-DRB1*04:02 GSPLSLNMARKTLNSL GSPLSLNMARKALNSL 1148 482
HLA-DRB1*11:01 LRLGSPLSLNMARKTLN LRLGSPLSLNMARKALN 269 113
HLA-DRB1*10:01 PLSLNMARKTLNSLEDK PLSLNMARKALNSLEDK 207 87
HLA-DRB1*04:02 LGSPLSLNMARKTLN LGSPLSLNMARKALN 844 355
HLA-DPA1*04:01/DPB1*14:01 GSPLSLNMARKTLNSLE GSPLSLNMARKALNSLE 965 406
HLA-DQA1*01:03/DQB1*05:03 LGSPLSLNMARKTLNSLEDK LGSPLSLNMARKALNSLEDK 786 331
HLA-DQA1*01:03/DQB1*05:03 GSPLSLNMARKTLNSLE GSPLSLNMARKALNSLE 1092 460
HLA-DRB1*08:04 RLGSPLSLNMARKTLN RLGSPLSLNMARKALN 451 190
HLA-DRB1*04:02 LGSPLSLNMARKTLNSLEDK LGSPLSLNMARKALNSLEDK 1061 447
HLA-DPA1*04:01/DPB1*14:01 SLNMARKTLNSLEDKAFQL SLNMARKALNSLEDKAFQL 1186 500
HLA-DRB1*11:01 RLGSPLSLNMARKTLNSLED RLGSPLSLNMARKALNSLED 83 35
HLA-DRB1*08:04 GSPLSLNMARKTLNSL GSPLSLNMARKALNSL 173 73
HLA-DRB1*08:02 SPLSLNMARKTLNSLED SPLSLNMARKALNSLED 218 92
HLA-DRB1*11:04 RLGSPLSLNMARKTLNSLE RLGSPLSLNMARKALNSLE 116 49
HLA-DRB1*11:04 RLGSPLSLNMARKTLNSLED RLGSPLSLNMARKALNSLED 71 30
HLA-DQA1*01:03/DQB1*05:03 SPLSLNMARKTLNSLED SPLSLNMARKALNSLED 1143 483
HLA-DRB1*04:04 RLGSPLSLNMARKTLNS RLGSPLSLNMARKALNS 546 231
HLA-DRB1*10:01 PLSLNMARKTLNSLED PLSLNMARKALNSLED 241 102
HLA-DRB1*04:04 LGSPLSLNMARKTLNS LGSPLSLNMARKALNS